Navigation Links
Preventive Use of Antibiotics Cuts ICU Deaths
Date:12/31/2008

Dutch researchers admit more review is needed on potential antibiotic resistance

WEDNESDAY, Dec. 31 (HealthDay News) -- Giving people antibiotics before they were admitted to a hospital intensive care unit led to a drop in patient deaths, a new Dutch study found.

The findings should settle a long-running debate on whether the use of antibiotics as a preventive measure for intensive care patients offsets the risk of possible antibiotic resistance, said study author Dr. Anne Marie de Smet, an anesthesiologist-intensivist at University Medical Center Utrecht.

The study, published in the Jan. 1 issue of the New England Journal of Medicine, included nearly 6,000 patients treated at 13 hospitals in the Netherlands between 2004 and 2006.

For the study, the researchers compared the use of two types of antibiotic treatments to standard ICU care. They divided the patients into three groups. The first group received an oral antibiotic paste four times a day. The second group received antibiotics through a gastric tube in the intestinal tract and by intravenous drip, as well as the antibiotic paste. The third group received standard ICU care.

All the patients were expected to be on a ventilator for at least two days and/or to be admitted to the ICU for at least three days.

After four weeks, the preventive use of antibiotics reduced the number of deaths by 3.5 percent in the group receiving oral antibiotic paste as well as antibiotics in the intestinal tract and by intravenous drip, and by 2.9 percent in the oral antibiotic paste group. The difference between the two groups treated with antibiotics was not significant, the researchers said.

What's more, the number of antibiotic-resistant bacteria did not increase in patients receiving antibiotic treatment, the researchers said.

"I believe we should revise the antibiotic policy for the ICU," de Smet said in a news release. "Because the study was conducted in 13 Dutch hospitals, the conclusions can be implemented throughout the country. We have seen that using antibiotics clearly results in a reduction in the number of deaths, and ICUs should make use of this knowledge."

The researchers acknowledged that the study was too short to determine how antibiotic resistance might develop in the long term, adding this will require additional research.

More information

To learn more about antibiotics, visit the U.S. National Library of Medicine.



-- HealthDay staff



SOURCE: University Medical Center Utrecht, the Netherlands, news release, Dec. 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. News of Declining Cancer Deaths Underscores the Power of Preventive Screening
2. More Women Choosing Preventive Double Mastectomy
3. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
4. HSA Plans are Covering Preventive Care on a First-Dollar Basis
5. US Preventive Medicine(R) Says Study on Heart Disease-related Deaths Demonstrates Need for Preventive Medical Care
6. U.S. Preventive Medicine to Expand into England with iHealth UK Ltd.
7. New Study: Screening for Problem Drinking is One of the Most Cost-Effective Clinical Preventive Services
8. U.S. Preventive Medicine(R) Predicts Robust Growth Ahead
9. Co-Pays Contribute to Drop in Preventive Care
10. American College of Preventive Medicine calls on ABC to cancel Eli Stone episode
11. Caregiver Magazine Urges Preventive Measures Against Wandering, Falls, Abuse
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic ... Frederick area economy by obtaining investment capital for emerging technology companies. SCP ... that have already resulted in more than a million dollars of capital investment ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group ... Tournament held on June 20th at the Woodmont Country Club at 1201 Rockville ... an organization dedicated to helping service members that have been wounded in battle and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... ITASCA, Ill. , June 23, 2016  In a startling ... states are failing their residents by lacking a comprehensive, proven plan ... , a definitive ranking of how states are tackling the ... rating to only four states – Kentucky , ... and Vermont . Of the 28 failing states, ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
Breaking Medicine Technology: