Navigation Links
Preventive Use of Antibiotics Cuts ICU Deaths
Date:12/31/2008

Dutch researchers admit more review is needed on potential antibiotic resistance

WEDNESDAY, Dec. 31 (HealthDay News) -- Giving people antibiotics before they were admitted to a hospital intensive care unit led to a drop in patient deaths, a new Dutch study found.

The findings should settle a long-running debate on whether the use of antibiotics as a preventive measure for intensive care patients offsets the risk of possible antibiotic resistance, said study author Dr. Anne Marie de Smet, an anesthesiologist-intensivist at University Medical Center Utrecht.

The study, published in the Jan. 1 issue of the New England Journal of Medicine, included nearly 6,000 patients treated at 13 hospitals in the Netherlands between 2004 and 2006.

For the study, the researchers compared the use of two types of antibiotic treatments to standard ICU care. They divided the patients into three groups. The first group received an oral antibiotic paste four times a day. The second group received antibiotics through a gastric tube in the intestinal tract and by intravenous drip, as well as the antibiotic paste. The third group received standard ICU care.

All the patients were expected to be on a ventilator for at least two days and/or to be admitted to the ICU for at least three days.

After four weeks, the preventive use of antibiotics reduced the number of deaths by 3.5 percent in the group receiving oral antibiotic paste as well as antibiotics in the intestinal tract and by intravenous drip, and by 2.9 percent in the oral antibiotic paste group. The difference between the two groups treated with antibiotics was not significant, the researchers said.

What's more, the number of antibiotic-resistant bacteria did not increase in patients receiving antibiotic treatment, the researchers said.

"I believe we should revise the antibiotic policy for the ICU," de Smet said in a news release. "Because the study was conducted in 13 Dutch hospitals, the conclusions can be implemented throughout the country. We have seen that using antibiotics clearly results in a reduction in the number of deaths, and ICUs should make use of this knowledge."

The researchers acknowledged that the study was too short to determine how antibiotic resistance might develop in the long term, adding this will require additional research.

More information

To learn more about antibiotics, visit the U.S. National Library of Medicine.



-- HealthDay staff



SOURCE: University Medical Center Utrecht, the Netherlands, news release, Dec. 31, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. News of Declining Cancer Deaths Underscores the Power of Preventive Screening
2. More Women Choosing Preventive Double Mastectomy
3. Chair of U.S. Preventive Services Task Force Pledges to Recommend Re-evaluation of Recent Glaucoma Findings
4. HSA Plans are Covering Preventive Care on a First-Dollar Basis
5. US Preventive Medicine(R) Says Study on Heart Disease-related Deaths Demonstrates Need for Preventive Medical Care
6. U.S. Preventive Medicine to Expand into England with iHealth UK Ltd.
7. New Study: Screening for Problem Drinking is One of the Most Cost-Effective Clinical Preventive Services
8. U.S. Preventive Medicine(R) Predicts Robust Growth Ahead
9. Co-Pays Contribute to Drop in Preventive Care
10. American College of Preventive Medicine calls on ABC to cancel Eli Stone episode
11. Caregiver Magazine Urges Preventive Measures Against Wandering, Falls, Abuse
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are ... with endometriosis. These women need a treatment plan to not only alleviate symptoms ... can help for preservation of fertility and ultimately achieving a pregnancy. The specialists ...
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 ... the addition of the " Global Markets for ... This report focuses on ... updated review, including its applications in various applications. The ... which includes three main industries: pharmaceutical and biotechnology, food ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
Breaking Medicine Technology: