Navigation Links
Preventing toxic shock syndrome and other severe diseases
Date:7/30/2009

A researcher at The University of Western Ontario has received over $603,000 from the Canadian Institutes of Health Research (CIHR) to investigate how and why a group of bacterial toxins leads to the development of toxic shock syndrome and other serious diseases. John McCormick is an associate professor in the Department of Microbiology and Immunology at the Schulich School of Medicine & Dentistry, and a scientist with the Lawson Health Research Institute. His research is one of 18 projects at Western and Lawson to receive new CIHR operating grants totaling more than $9.55 million.

"We are looking at how these superantigen toxins bind to proteins on the surface of white blood cells. This binding causes the over-activation of the immune system which can result in the patient developing shock," says McCormick. The bacteria that produce these toxins include Streptococcus pyogenes (responsible for flesh-eating disease) and Staphylococcus aureus, including methicillin-resistant S. aureus, also known as the "MRSA" superbug.

"A patient can have a localized infection, for example, a staph infection in their toe, and that bacteria will release toxins which will go systemic, all through the body, even though the infection hasn't spread. The infection can be treated with antibiotics, but that won't have any affect on the toxins," explains McCormick. "By understanding how these toxins work, we can look at developing drug inhibitors that will target and neutralize the toxins."

On the flip side, McCormick believes these toxins could be utilized to fight cancer. "We know these toxins cause potent activation of the immune system, so if we could engineer them to bind only to cancer cells, we could get the immune system to destroy the cancer. That's a long-term goal we have."


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1

Related medicine news :

1. Blood-flow detector software show promise in preventing brain damage
2. Preventing variceal bleeding
3. OSHA Issues Draft Ergonomics Guidelines on Preventing Musculoskeletal Injuries in Shipyards
4. Preventing or reducing enlarged heart decreases risk of heart failure
5. Pill Equals Injection in Preventing Clots After Hip Replacement
6. Treating obstructive sleep apnea, preventing heart attacks and strokes
7. Preventing lung scarring may extend lives of lung cancer patients
8. Preventing or reducing enlarged heart may decrease risk for diabetes
9. Study shows drug effective in treating, preventing breast cancer
10. Good Hygiene Is Key to Preventing MRSA
11. Preventing Cancer, This Week on Your Cancer Today(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance ... care insurance companies have a waiver for care if the client has a cognitive ... the family pays for care, is often waived, so the benefits from their insurance ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Yisrayl Hawkins, Pastor ... that explains one of the most popular and least understood books in the Holy ... and puzzling descriptions that have baffled scholars for centuries. Many have tossed it off ...
(Date:10/13/2017)... , ... October 13, 2017 , ... “America On The ... identity. “America On The Brink” is the creation of published author, William Nowers. ... great-grandchildren. As a WWII veteran, he spent thirty years in the Navy. ...
(Date:10/12/2017)... ... 2017 , ... The company has developed a suite of ... authorities worldwide. From Children’s to Adults 50+, every formula has been developed by ... , These products are also: Gluten Free, Non-GMO, Vegan, Soy Free, Non-Dairy*, Preservative ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... CAESAREA, Israel and NEW YORK , Sept. ... company with mobile health and big data solutions, today announced that its ... today. Please check your local TV listings for when The Dr. Oz ... ... ninth season this month. ...
(Date:9/23/2017)... Janssen Biotech, Inc. (Janssen) announced today that ... U.S. Food and Drug Administration (FDA) for the Biologics ... treatment of moderately to severely active rheumatoid arthritis (RA). ... needed to further evaluate the safety of sirukumab in ... "We are disappointed ...
(Date:9/19/2017)... HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that ... developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D and ...
Breaking Medicine Technology: