Navigation Links
Preventing toxic shock syndrome and other severe diseases
Date:7/30/2009

A researcher at The University of Western Ontario has received over $603,000 from the Canadian Institutes of Health Research (CIHR) to investigate how and why a group of bacterial toxins leads to the development of toxic shock syndrome and other serious diseases. John McCormick is an associate professor in the Department of Microbiology and Immunology at the Schulich School of Medicine & Dentistry, and a scientist with the Lawson Health Research Institute. His research is one of 18 projects at Western and Lawson to receive new CIHR operating grants totaling more than $9.55 million.

"We are looking at how these superantigen toxins bind to proteins on the surface of white blood cells. This binding causes the over-activation of the immune system which can result in the patient developing shock," says McCormick. The bacteria that produce these toxins include Streptococcus pyogenes (responsible for flesh-eating disease) and Staphylococcus aureus, including methicillin-resistant S. aureus, also known as the "MRSA" superbug.

"A patient can have a localized infection, for example, a staph infection in their toe, and that bacteria will release toxins which will go systemic, all through the body, even though the infection hasn't spread. The infection can be treated with antibiotics, but that won't have any affect on the toxins," explains McCormick. "By understanding how these toxins work, we can look at developing drug inhibitors that will target and neutralize the toxins."

On the flip side, McCormick believes these toxins could be utilized to fight cancer. "We know these toxins cause potent activation of the immune system, so if we could engineer them to bind only to cancer cells, we could get the immune system to destroy the cancer. That's a long-term goal we have."


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Page: 1

Related medicine news :

1. Blood-flow detector software show promise in preventing brain damage
2. Preventing variceal bleeding
3. OSHA Issues Draft Ergonomics Guidelines on Preventing Musculoskeletal Injuries in Shipyards
4. Preventing or reducing enlarged heart decreases risk of heart failure
5. Pill Equals Injection in Preventing Clots After Hip Replacement
6. Treating obstructive sleep apnea, preventing heart attacks and strokes
7. Preventing lung scarring may extend lives of lung cancer patients
8. Preventing or reducing enlarged heart may decrease risk for diabetes
9. Study shows drug effective in treating, preventing breast cancer
10. Good Hygiene Is Key to Preventing MRSA
11. Preventing Cancer, This Week on Your Cancer Today(TM)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... (PRWEB) August 19, 2014 Grande ... named the winner of the 2014 Independent Cosmetics ... home the first place position in “Product Innovation; ... specially-formatted eyeliner, which also includes a lash enhancement ... color, plus lash-boosting technology. , This ...
(Date:8/19/2014)... 2014 In honor of National Dog Day on ... old furry friend by offering tips on caring for aging dogs. ... more. Because of this, dog owners need to realize the dog’s ... age, their needs change. They will not want to spend as ... used to. Because of this, pet owners should consider altering the ...
(Date:8/19/2014)... Following the completion of a $16 million rooms renovation in ... to debut the highly anticipated final phase of its $20 ... all public spaces to match the fresh look and feel ... experience at 1823 Kitchen and Bar and an innovative tech ... 1823 Kitchen and Bar, Grand Hyatt Tampa Bay has added ...
(Date:8/19/2014)... admitted to U.S. hospitals cannot smoke during their stay and ... few are able to stay smoke-free after returning home. ... JAMA describes a program that increased the proportion ... more than 70 percent. The system used interactive voice ... and stop-smoking medication for three months after smokers left the ...
(Date:8/19/2014)... Philadelphia, PA, August 19, 2014 Warfarin, the ... competition from new options in the anticoagulant drug ... study documents the rapid adoption of these novel ... NOACs accounted for 62% of all new anticoagulant ... drug costs. Findings are published in The ...
Breaking Medicine News(10 mins):Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 2Health News:GrandeLINER™ Wins Independent Cosmetics Manufacturers & Distributors Award 3Health News:The Puppy Store Helps Pet Owners Care for Aging Dogs 2Health News:Grand Hyatt Tampa Bay Hotel Unveils the Finishing Touches of Its $20 Million Makeover 2Health News:Extended support helps patients stay smoke-free after hospital discharge 2Health News:Novel oral anticoagulant prescriptions soar, but at a high cost 2Health News:Novel oral anticoagulant prescriptions soar, but at a high cost 3
... begun work into improving the lives of thousands of Cystic ... US-Ireland Research and Development Partnership grant. , The grant ... in the USA with funding for the Queen,s component provided ... Public Health Agency), Northern Ireland and the Medical Research Council. ...
... , THURSDAY, Feb. 3 (HealthDay News) -- A special ... disorder (ADHD) in young children, a new study suggests. ... 8 were placed on a diet containing no processed ... percent of them. And, when suspected trouble foods were ...
... bone marrow to become embryonic-like stem cells, a team ... the onset of the blood cancer leukemia in the ... blood cells obtained from a patient with leukemia," says ... directed a study aimed at generating all-purpose stem cells ...
... -- A single dose of the H1N1 swine flu vaccine ... study found. In order to assess the effectiveness of ... -- Canadian researchers looked at 552 patients with flu-like illness ... Dec. 5, 2009. Pandemic H1N1 was detected in 209 ...
... News) -- If you tend to overindulge in food and ... things you can do to ease the ill effects you ... Dr. Cynthia Yoshida offers the following suggestions: Stay ... Caffeine-free, non-carbonated drinks, such as water, can help lessen the ...
... (HealthDay News) -- The average starting salary for a female ... a huge increase from the $3,600 gap in 1999, finds ... difference isn,t known because it isn,t explained by gender differences ... researchers said. The study authors analyzed survey data from ...
Cached Medicine News:Health News:$2.8 million grant boosts cystic fibrosis research at Queen's 2Health News:Restrictive Diet May Reduce ADHD Symptoms 2Health News:Restrictive Diet May Reduce ADHD Symptoms 3Health News:Restrictive Diet May Reduce ADHD Symptoms 4Health News:New induced stem cells may unmask cancer at earliest stage 2Health News:Gender Gap in Starting Doctor Pay Grows 2
(Date:8/19/2014)... /PRNewswire-iReach/ -- ChemImage founder and CTO, Patrick J. ... an innovative diagnostic procedure for the detection of colorectal ... Disease (SPEC) conference in Krakow, Poland ... of in vitro Diagnostics for Detection of Colorectal Cancer ... conference poster session on Tuesday, August 19, 2014 from ...
(Date:8/19/2014)...  As power morcellator lawsuits continue to mount ... notes that women in need of fibroid removal ... options that do not involve the use of ... report published by The Wall Street Journal on ... mini-laparotomy and vaginal hysterectomy. Non-surgical options for shrinking ...
(Date:8/19/2014)... 2014 Research and Markets has announced ... Global Strategic Business Report" report to their offering. ... Growth Hormone Drugs in US$ Million by the following Brands: ... report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , and Rest ...
Breaking Medicine Technology:ChemImage Scientists Present Latest Developments for in vitro Detection of Colorectal Cancer Using Raman Molecular Imaging (RMI) at International Conference Focused on Biomedical Applications of Raman Spectroscopy 2As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 2As Morcellator Lawsuits Mount, Bernstein Liebhard LLP Notes Report Detailing Alternatives to Uterine Morcellation 3Global Human Growth Hormone Drugs - Strategic Business Report 2014 2
... Sept. 1, 2011 Kimberly-Clark Health Care (KCHC) ... price increase on synthetic exam gloves due to ... materials, particularly butadiene and acrylonitrile.   ... raw materials along with inflationary pressures have been ...
... 1, 2011 Today, Osseon® Therapeutics, Inc. launched ... newest in Osseon,s suite of minimally invasive products ... (Photo:   http://photos.prnewswire.com/prnh/20110901/SF61461 ) The ... entire vertebral body. The Osseoplasty™ procedure offers unparalleled ...
Cached Medicine Technology:Osseon® Announces Commercial Release of Osseoflex®SN (Steerable Needle) 2
96-Well PCR Plate Sealing Mat...
Easy to pierce, remove using foil stripper...
Inquire...
... Heat Sealing Foil and Heat Sealing Film each ... allow safe and easy sample storage. In automated ... with standard pipette tips. The Heat Sealing Film ... in the plates. Heat Sealing Foil is removed ...
Medicine Products: