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Pressure BioSciences, Inc. Provides Corporate Update
Date:3/20/2009

SOUTH EASTON, Mass., March 20 /PRNewswire-FirstCall/ -- Pressure BioSciences, Inc. (Nasdaq: PBIO) ("PBI" and the "Company") today provided an update on various corporate activities, including (1) the receipt of a Phase I Small Business Innovation Research ("SBIR") Grant from the National Institutes of Health ("NIH"), (2) a presentation by Dr. Alexander Ivanov of the Harvard School of Public Health on the significant advantages in throughput and reproducibility of the Company's pressure cycling technology ("PCT"), and (3) the winning by scientists from PBI and the Harvard School of Public Health of the Journal of Biomolecular Techniques ("JBT") Outstanding Manuscript Award.

1) Phase I SBIR Grant Award: PBI was recently notified by the National Institute of Allergy and Infectious Diseases ("NIAID") of the NIH that it had been awarded a Phase I SBIR grant (1R43A1081518-01) for a total of $109,998 to be billed over six months. Entitled "Sample Preparation Using Pressure for Microbiome Studies and Clinical Diagnostics", the grant will help fund research studies focused on discovering and cataloging the microbes that live on and in the human body. The approved research plan calls for PCT to be used to prepare all samples in the study for analysis. If the Phase I SBIR studies are successful, the Company expects to submit a request for Phase II SBIR funding later this year. Typical Phase II funding is for approximately $1 million and is billed over a two year period. It should be noted that the NIH has recently initiated the Human Microbiome Project, a logical extension of the recently completed Human Genome Project, with the mission to comprehensively characterize microbes that inhabit the human body, and to analyze their role in human health and disease.

2) Presentation by Dr. Alexander Ivanov
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