Navigation Links
Preoperative/neoadjuvant therapy in pancreatic cancer
Date:4/20/2010

In research published this week in PLoS Medicine, Jrg Kleeff from Technische Universitt Mnchen, and colleagues suggest that patients with apparently locally non-resectable tumors should be included in neoadjuvant protocols. The authors systematically reviewed studies concerning the effects of neoadjuvant therapy on tumor response, toxicity, resection, and survival percentages in pancreatic cancer.

Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer-related mortality and is associated with an extremely poor prognosis, with a median survival of 5-8 months. At present, the only chance for cure and prolonged survival is surgical resection. Currently approximately 10%-20% of patients are considered candidates for such resection.

The authors examined 111 studies, involving 4,394 patients, and found that a third of patients initially judged unresectable were able to undergo resection after neoadjuvant therapy. These patients were then found to have a similar survival rate to patients judged resectable before neoadjuvant treatment (the average survival time being 20.5 months after resection). Although randomized trials are now needed to confirm this finding, they suggest that patients presenting with locally advanced/unresectable tumors should be offered neoadjuvant therapy and then re-evaluated for resection.


'/>"/>

Contact: Andrew Hyde
press@plos.org
44-122-346-3330
Public Library of Science
Source:Eurekalert

Page: 1

Related medicine news :

1. Targeted therapy prolongs life in patients with HER2-positive breast cancer
2. PharmMD Secures Investments to Fund New Opportunities in Medication Therapy Management
3. More smokers kick the habit with extended nicotine patch therapy, Penn research shows
4. Experts Issue Warning on Prostate Hormone Therapy
5. ASGCT: Gene Therapy Shows Promise for Patients with Pompe Disease
6. AAPM statement on quality radiation therapy
7. Congress Urged to Take Immediate Action to Ensure Frail Patients Continue to Receive Critical Therapy Services
8. Intensive Insulin Therapy Wont Boost Septic Shock Survival
9. News brief: Dermatologic infections in cancer patients treated with EGFRI therapy
10. A new target for lymphoma therapy
11. NCCN Guidelines for Non-Small Cell Lung Cancer Updated to Incorporate Maintenance Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... January 17, 2017 , ... Recently, patients and staff from A ... other volunteers and organizations in support of the annual Binder Park Zoo Halloween celebration ... up in colorful costumes of all designs coming out to enjoy games, face painting, ...
(Date:1/16/2017)... ... ... Anybody who may be looking for a substance abuse rehabilitation program with ... a holistic treatment center for addiction located in Marne, MI. This video, which can ... and staff that visited the 2016 Recovery Palooza support event in nearby Grand Rapids. ...
(Date:1/16/2017)... ... January 16, 2017 , ... Atlanta-based incentive company ... in the wheelchair accessibility industry, BraunAbility . Incentive Solutions will provide BraunAbility ... accessible vehicles. With this new incentive plan, BraunAbility plans to continue their tradition ...
(Date:1/16/2017)... (PRWEB) , ... January 16, 2017 , ... One thing ... only to treat, but to test for, as well. The money spent screening for ... year.(1) Doctors in the U.S. screen patients for cancer more than in any other ...
(Date:1/15/2017)... ... 15, 2017 , ... Going above and beyond the practical ... better communities around the world by offering the Gensuite team and their services ... team members to become involved in a cause that is bigger than themselves ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... TORONTO , Jan. 16, 2017 When synthetic ... to market their product as top-rate. They offered free samples, ... top-notch customer service. Soon, business was booming. ... often described as 100 times more powerful than morphine, has ... in last 2 years. One dealer,s recorded fentanyl ...
(Date:1/16/2017)... PUNE, India , January 16, 2017 /PRNewswire/ ... Research, titled, "Vital Signs Monitoring Devices Market by Type and ... that the global vital signs monitoring devices market size was ... $5,491 million by 2022, growing at a CAGR of 5.8% ... was the leading regional market in global vital signs monitoring ...
(Date:1/16/2017)... PUNE, India , January 16, 2017 ... & Its Derivatives Market by Product Type (Methyl, ... Personal Care, Foods & Beverages, Surface Coatings ... 2021", published by MarketsandMarkets, the market was ... and is projected to reach USD 6.41 ...
Breaking Medicine Technology: