Navigation Links
Prenatal tests more informative using microarray technology, find GW researchers
Date:12/6/2012

WASHINGTON A new method for detecting abnormalities in unborn children is providing physicians with more information to analyze the results than conventional, microscopic testing, according to two George Washington University researchers.

Elizabeth Thom, research professor of epidemiology and biostatistics, and Julia Zachary, senior research scientist, are co-authors of the lead article appearing in the current issue of the New England Journal of Medicine showing that microarray technology provides a more comprehensive result from genetic testing during prenatal care of women than the current method of testing, called karyotyping, which relies on visual analysis of the fetal chromosomes.

"Microarray analysis of blood is now standard of care when children or adults present with undiagnosed neurodevelopmental problems since there are a number of serious syndromes that involve small changes on chromosomes which are not seen through a microscope," explained Dr. Thom. "It is a natural extension to want to identify these syndromes prenatally, but research into how to interpret the data is essential."

The GW Biostatistics Center in Rockville, Md. where Dr. Thom and Ms. Zachary are both based was the coordinating center for the multi-site trial. The research was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and led by Columbia University Medical Center.

The trial involved 4,400 patients at 29 centers nationwide and the data took more than four years to compile. The trial's cohort consisted of women over the age of 18 but predominantly over 30, whose fetuses were shown in early screenings to be at a heightened risk for Down syndrome or to have structural abnormalities found through an ultrasound.

The trial found that microarray analysis performed as well as karyotyping in identifying common outcomes involving an abnormal number of chromosomes, which can cause genet
'/>"/>

Contact: Latarsha Gatlin
lgatlin@gwu.edu
202-994-5631
George Washington University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Documenting womens experiences with chromosome abnormalities found in new prenatal test
2. Illy Trieste Science Prize: Yuk Ming Dennis Lo awarded for non-invasive prenatal diagnosis
3. Prenatal diagnosis of congenital heart disease increases maternal stress, depression, and anxiety
4. Prenatal exposure to pesticide additive linked with childhood cough
5. Prenatal maternal smoking associated with increased risk of adolescent obesity
6. Prenatal Exposure to Common Household Chemical Linked to Eczema
7. Prenatal exposure to common household chemical increases risk for childhood eczema, study says
8. Prenatal exposure to pollution especially dangerous for children with asthma
9. ACA: More than a million women could gain access to potentially life saving tests for cancer
10. Meth vaccine shows promising results in early tests
11. Intervention helps children with sickle cell disease complete MRI tests without sedation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... The U.S. Food & Drug ... Entertainment Industries Council (EIC) have teamed with entertainment ... Story on a first-of-its-kind Decorative Contact Lens ... illegal and unsafe lens use to the forefront. ... tens-of-thousands, is now releasing its second production which ...
(Date:7/24/2014)... -- Some babies are at risk for autism because they ... find new ways to detect Autism Spectrum Disorder (ASD) earlier ... with others and how they relate to the possibility and ... to understand the connection between early joint attention before one ... form of communication that develops toward the end of the ...
(Date:7/24/2014)... Skirt Sports, the innovative women’s running apparel brand is proud ... from an idea by professional triathlete Nicole DeBoom during a ... this one innovative piece of running gear revolutionized the fitness ... in Wisconsin to incorporate Skirt Sports, the first company to ... I drew the first sketch of a running skirt on ...
(Date:7/24/2014)... July 24, 2014 The report, “Feed ... Synthetic), by Livestock (Swine, Poultry, Cattle, Pets, Aquaculture, and ... and segments the feed palatability enhancers & modifiers market ... in terms of value, of types of feed flavors, ... tables and 17 figures spread through 275 pages and ...
(Date:7/24/2014)... County high school students are smoking tobacco products at ... to new data from the Prevention Research Center for ... 2013, more than 22 percent, or one in five ... within the prior 30 days. , Equally surprising is ... hookahs, or water pipes, more than cigarettes matching ...
Breaking Medicine News(10 mins):Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 2Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 3Health News:Optometric Professionals Team with Hollywood for Second Installment of Video Campaign 4Health News:Early warning sign for babies at risk of autism 2Health News:Skirt Sports Celebrates Its 10-Year Anniversary and 10 Years of the Running Skirt With a Virtual Community Building Run 2Health News:Skirt Sports Celebrates Its 10-Year Anniversary and 10 Years of the Running Skirt With a Virtual Community Building Run 3Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 2Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 3Health News:Feed Palatability Enhancers & Modifiers Market Worth $3172.6 Million by 2019 - Report by MarketsandMarkets 4Health News:Cuyahoga County high school students smoking at the same rate as adults 2Health News:Cuyahoga County high school students smoking at the same rate as adults 3Health News:Cuyahoga County high school students smoking at the same rate as adults 4
... PALO ALTO, Calif., Feb. 1 Lifespring Health,sponsors the ... Run.,This is an important charity event benefiting the Hemophilia ... Disabilities and,the Koret Family House., Set to take ... Marathon,Championship certified 13.1 mile course is ranked as one ...
... non-REM sleep (45 minutes) obtained during a daytime nap clearly ... published in the February 1 issue of the journal SLEEP. ... the Center for Sleep and Cognition and the department of ... males, 22 females) with an average age of 23.3 years. ...
... North Carolina researchers have found that women with irritable bowel ... have a heightened brain response to pain that makes them ... affects 10 to 15 percent of the population and causes ... , Researchers used brain imaging to show that patients ...
... Business Leaders Learn How Their Employee Health Benefit ... Business owners and human,resource executives grappling with ... and cost effective found out how their plans,compare ... Embassy Suites,Parsippany. Scott Rappoport, a 25-year veteran of ...
... Gastric Band Surgery Performed Each Month in ... LONDON, February 1 Today saw the launch ... information and support to people considering obesity surgery. To,coincide ... new survey reveal,widespread confusion over the causes of obesity ...
... getting preventive treatments , , THURSDAY, Jan. 31 (HealthDay ... hospitals worldwide risk developing dangerous blood clots known ... that could prevent the condition, a large international ... recognized to be one of the most common ...
Cached Medicine News:Health News:Journal Sleep: Study concludes a daytime nap can benefit a person's memory performance 2Health News:Key to Attracting and Retaining Quality Employees: Benefits 2Health News:Key to Attracting and Retaining Quality Employees: Benefits 3Health News:Lose Weight Gain Life: New Website to Help People Seeking Information on Obesity Surgery 2Health News:Lose Weight Gain Life: New Website to Help People Seeking Information on Obesity Surgery 3Health News:Hospital Patients' Blood Clot Risk High 2Health News:Hospital Patients' Blood Clot Risk High 3
(Date:7/24/2014)... -- Delivery of the Report will take 2-3 ... Photo - http://photos.prnewswire.com/prnh/20140723/129707 ... on Global and Chinese Hemodialysis Machine industry. The ... Machine including its classification, application and manufacturing technology. ... manufacturers of Hemodialysis Machine listing their product specification, ...
(Date:7/24/2014)... 24, 2014 Cancer patients in the west of ... cancer treatment closer to home when a new radiotherapy center ... Medical Systems (NYSE: VAR ) has been selected ... in June for four TrueBeam™ medical linear accelerators. ... and efficient radiotherapy and radiosurgery treatments, will replace older treatment ...
(Date:7/24/2014)...  Blueprint Medicines (Blueprint), a leader in discovering highly ... announced the appointment of Jeffrey Albers as ... Algeta ASA, where he served on the executive management ... Bayer. Mr. Albers succeeds Alexis Borisy , co-founder ... Rock Ventures, who will remain an active member of ...
Breaking Medicine Technology:Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 2Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 3Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 4Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 5Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 2Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 3Blueprint Medicines Appoints Jeffrey Albers as Chief Executive Officer 2
... Nov. 14, 2011 Tengion, Inc. (Nasdaq: ... of a restructuring plan, and reported its financial results ... restructuring plan is designed to fund the Company,s lead ... the Company,s anticipated cash utilization.  As a result of ...
... Texas, Nov. 14, 2011 Novation commends the IMS ... raising awareness of the drug shortage crisis facing America,s ... Look at Products, Suppliers and Volume Volatility."   ... 2011 Executive Order, is helping bring much-needed attention to ...
Cached Medicine Technology:Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 2Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 3Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 4Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 5Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 6Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 7Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 8Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 9Tengion Provides Business Update and Reports Third Quarter 2011 Financial Results 10Novation Applauds the IMS Institute for Healthcare Informatics for Calling Attention to the Drug Shortage Crisis Facing American Hospitals 2Novation Applauds the IMS Institute for Healthcare Informatics for Calling Attention to the Drug Shortage Crisis Facing American Hospitals 3
The XT-1800i is a compact, high performance, automated hematology analyzer that provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test re...
The XT-2000i is a compact, high performance, automated hematology analyzer that provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test re...
The XE-2100L automated hematology analyzer features new hematology parameters as NRBC, IRF, and HPC that offer valuable and accurate clinical information....
The XE-2100 automated hematology analyzer features new hematology parameters as NRBC, IRF, and HPC that offer valuable and accurate clinical information....
Medicine Products: