Navigation Links
Prenatal inflammation linked to autism risk
Date:1/24/2013

Maternal inflammation during early pregnancy may be related to an increased risk of autism in children, according to new findings supported by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health. Researchers found this in children of mothers with elevated C-reactive protein (CRP), a well-established marker of systemic inflammation.

The risk of autism among children in the study was increased by 43 percent among mothers with CRP levels in the top 20th percentile, and by 80 percent for maternal CRP in the top 10th percentile. The findings appear in the journal Molecular Psychiatry and add to mounting evidence that an overactive immune response can alter the development of the central nervous system in the fetus.

"Elevated CRP is a signal that the body is undergoing a response to inflammation from, for example, a viral or bacterial infection," said lead scientist on the study, Alan Brown, M.D., professor of clinical psychiatry and epidemiology at Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, and Mailman School of Public Health. "The higher the level of CRP in the mother, the greater the risk of autism in the child."

Brown cautioned that the results should be viewed in perspective since the prevalence of inflammation during pregnancy is substantially higher than the prevalence of autism.

"The vast majority of mothers with increased CRP levels will not give birth to children with autism," Brown said. "We don't know enough yet to suggest routine testing of pregnant mothers for CRP for this reason alone; however, exercising precautionary measures to prevent infections during pregnancy may be of considerable value."

"The brain develops rapidly throughout pregnancy," said Linda Birnbaum, Ph.D., director of NIEHS, which funds a broad portfolio of autism and neurodevelopmental-related research. "This has import
'/>"/>

Contact: Ed Kang
kanges@niehs.nih.gov
919-541-1993
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Prenatal Antidepressants Dont Raise Fetal, Infant Death Risk: Study
2. Prenatal tests more informative using microarray technology, find GW researchers
3. Documenting womens experiences with chromosome abnormalities found in new prenatal test
4. Illy Trieste Science Prize: Yuk Ming Dennis Lo awarded for non-invasive prenatal diagnosis
5. Prenatal diagnosis of congenital heart disease increases maternal stress, depression, and anxiety
6. Prenatal exposure to pesticide additive linked with childhood cough
7. Prenatal maternal smoking associated with increased risk of adolescent obesity
8. Prenatal Exposure to Common Household Chemical Linked to Eczema
9. Prenatal exposure to common household chemical increases risk for childhood eczema, study says
10. Prenatal exposure to pollution especially dangerous for children with asthma
11. Neuroinflammation may be behind general-anesthesia-associated learning disabilities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Minn. (PRWEB) January 22, 2015 Blue Cross ... those Minnesotans who exemplify what it means to “Live Fearless.” ... chance for people to share their stories about how they ... or simply inspired others by living in the moment. By ...
(Date:1/22/2015)... 2015 Thousand of GranuFlo lawsuits ( ... its GranuFlo and NaturaLyte dialysis concentrates continue to move ... District Court, District of Massachusetts, Bernstein Liebhard LLP reports. ... has remanded a case filed by the state of ...
(Date:1/22/2015)... January 22, 2015 A study ... Medicine flagship journal Medicine & Science in Sports ... exercise may help reduce gastrointestinal (GI) problems associated ... , Participants in the double-blind, placebo-controlled study took ...
(Date:1/22/2015)... Payday lending practices in four southern states worsen ... to the states that permit them, according to a ... Race and Wealth. , While they generate hundreds of ... the same time substantially depress economic activity, according to ...
(Date:1/22/2015)... 22, 2015 Lower-Auto-Insurance.com has released a new blog ... a car for reducing the costs of an auto insurance ... be able to get lower prices for their vehicle insurance policies. ... role in determining policy costs. Because of this, drivers should ...
Breaking Medicine News(10 mins):Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2
... painkillers, especially the likes of Ibuprofen and Aspirin, which come ... out or exercise. A new study has suggested that the ... work out, may ease muscle pain by 50%. ... of kinesiology at the University of Georgia, Athens, 'A lot ...
... is only too happy to perform it. ... had been diagnosed with X-linked lymphoproliferative syndrome, //a rare genetic ... affected around 100 males worldwide. ,Life expectancy ... causes the immune system to respond abnormally to some viral ...
... San Antonio, Texas has come to the rescue of a ... choice. ,This clinic aids couples who are interested ... to choose the egg //and sperm donors. The couple after ... adults decides accordingly. The complete history of the donors is ...
... books, including old and rare manuscripts on the ancient Indian ... be built at the National Ayurveda Institute at a cost ... biggest ayurveda libraries in India. It will house national and ... information under one roof. ,'The budget has already ...
... at Monash University in Australia have developed a process for ... without any moving parts, potentially allowing doctors //to do blood ... new method uses the same principle that causes tea leaves ... stirred teacup, a phenomenon first explained by Einstein in the ...
... Publishing are excited to announce the publication of the ... issue of Wound Repair and Regeneration (WRR), the premier ... continued interest by the WHS membership and with a ... developed to establish guidelines for the treatment of chronic ...
Cached Medicine News:Health News:Work-outs, Not So Much of a ‘pain’ With Caffei 2Health News:Big Brother to the Rescue 2Health News:Einstein's Tea Leaves Inspire New Blood Separation Technique 2
(Date:1/23/2015)... , Jan. 23, 2015 A lot of discussion in ... for treating  certain illnesses, injuries, or conditions. As medical science ... treatment methods with ones that they consider to be more ... is not one textbook method of treatment that stands out ...
(Date:1/23/2015)... , Jan. 23, 2015  A new analysis of ... D 2015 enrollment data shows that 81 percent of ... access and extra discounts at certain pharmacies. The findings ... "Preferred pharmacy plans are now the foundation of Medicare ...
(Date:1/23/2015)... 2015 More than a third of reproductive-aged women enrolled ... private insurance, filled a prescription for an opioid pain medication ... week,s Morbidity and Mortality Weekly Report (MMWR). ... moderate to severe pain.  They are also found in some ...
Breaking Medicine Technology:No One-Size-Fits-All Remedy for Hernia Correction 2New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... Calif. , June 3 Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA ... will present during the Jefferies 2010 Global Life Sciences Conference.  The Alexza presentation ... ET .  The presentation will be webcast from the Grand Hyatt Hotel in ... , To ...
... ViroPharma Incorporated (Nasdaq: VPHM ) today announced that William Roberts ... Global Life Sciences Conference at 4:00 P.M. ET on Wednesday, ... in New York City . , ... Mr. Roberts also will present at the ThinkEquity Healthcare Conference at 1:30 ...
Cached Medicine Technology:Alexza Pharmaceuticals to Present at Jefferies 2010 Global Life Sciences Conference 2Alexza Pharmaceuticals to Present at Jefferies 2010 Global Life Sciences Conference 3ViroPharma to Participate in Two June Healthcare Investor Conferences 2
... ENA assays can be used to ... antibodies, which are associated with various ... lupus erythematosus (Lupus), Sjgren's syndrome, mixed ... scleroderma, polymyositis, dermatomyositis, and Raynaud's phenomenon. ...
... commonly prescribed for the prevention of life threatening ... However, a number of studies have shown that ... aspirin therapy to prevent a recurrent vascular event ... These people are at greater risk for a ...
... System is an embolic protection device that ... debris that may be dislodged during interventional ... components. The first is a guidewire-mounted filter, ... Other ancillary components supplied with the system ...
... is a simulator for intraocular surgery. The ... surgeon the feeling that he is experiencing ... surgeon uses instruments that feel and function ... through the EYESI microscope is similar to ...
Medicine Products: