Navigation Links
Prenatal exposure to pesticide additive linked with childhood cough
Date:9/5/2012

Children exposed in the womb to the widely used pesticide additive piperonyl butoxide (PBO) have heightened risk of noninfectious cough at ages 5 and 6, according to researchers at the Columbia Center for Children's Environmental Health (CCCEH) at the Mailman School of Public Health and of Columbia University Medical Center.

The findings, which appear in the August 31 online edition of the journal Environment International, support the premise that the children's respiratory system is susceptible to damage from toxic exposures during the prenatal period. A common symptom, childhood cough can disrupt normal daytime activities and interrupt sleep for both child and parent.

Piperonyl butoxide (PBO) is an organic compound used to bolster the effects of pyrethroid pesticides. Pyrethroids are the most commonly used pesticides for both professional pest control and non-professional residential use, according to a 2011 study by Mailman School researchers. Exposure to one pyrethroid, a variation of permethrin, was linked with increased risk for cough by age 5 in a 2009 study by Rachel Miller, MD. In the current study, Dr. Miller and colleagues sought to build on these findings by exploring the effects of subsequent exposure during childhood, looking specifically at the effects of PBO exposure.

Researchers looked at 224 mother-child pairs enrolled in the CCCEH birth cohort study of environmental exposures, examining measures of PBO and pyrethroid in personal air monitors worn by the mothers during pregnancy. Air samples also were collected from the home over the course of two weeks when children were between 5 and 6 years old. Questionnaires were used to evaluate respiratory outcomes.

Researchers found that children exposed to PBO during pregnancy had increased odds of reporting cough unrelated to cold or flu. Exposures to PBO during childhood were not a factor. There was no observed association between prenatal or childhood permethrin exposure and cough, something the researchers say may be explained by the fact that PBO is much easier to measure in air samples than permethrin. There was also no association with PBO or permethrin exposure and other respiratory outcomes like wheeze or asthma. While it is unclear whether the effect is due mainly to PBO itself or residential pyrethroids of which PBO is an indicator, it is important to remember, says Dr. Miller, that "these exposures may be a factor in a very common problem for childrencough."


'/>"/>

Contact: Timothy S. Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related medicine news :

1. Prenatal exposure to pollution especially dangerous for children with asthma
2. Prenatal exposure to common household chemical increases risk for childhood eczema, study says
3. Prenatal Exposure to Common Household Chemical Linked to Eczema
4. Prenatal maternal smoking associated with increased risk of adolescent obesity
5. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
6. Genetic variants, tobacco exposure and lung cancer risk
7. Leaded Gas Exposure Linked to Later Violence: Study
8. Majority of states fail to address youth exposure to alcohol marketing
9. Novel biomarkers reveal evidence of radiation exposure
10. Education May Protect Brain From Exposure to Solvents
11. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... ... 05, 2016 , ... In the fourth quarter of 2015, ... the La Valencia Hotel in San Diego, California to discuss changes in the ... most outstanding franchise, walking away with the coveted David Wright Award of Excellence. ...
(Date:2/5/2016)... ... 05, 2016 , ... Pivot Point Consulting, a leading national ... & Services for HIT Implementation Support & Staffing report with an outstanding score ... by healthcare executives, managers and clinicians representing over 4,500 hospitals and 2,500 clinics. ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Colorize ... from on one drop zone to the next using Colorize's dynamic moving camera. Colorize ... project. This package includes a 3D slideshow environment with 1 to 5 focus points ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Calls Blacklist has ... completely new user interface design and the developer has fixed known bugs within the ... want to on their phone while not consuming any of their device’s battery power ...
(Date:2/4/2016)... (PRWEB) , ... February 04, 2016 , ... ... "It's All About YOU Re-Treat" on February 19-21, 2016, in Southern California ... at Rancho Palos Verdes, California. These 30 professional speakers, including Clinical Psychologist and ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... , Feb. 4, 2016 For hospitals ... or those already participating in the program, the Health ... referred to as the , Mega-Guidance , could have ... guidance is published in September 2016. Essential ... and Service Marketing , summarizes the Mega-Guidance,s key proposed ...
(Date:2/4/2016)... -- Worldwide Radiology Oncology surgical robot markets are ... systems provide a way to improve traditional open ... systems pinpoint the delivery of radiation precisely, eliminating ... problem previously, limiting the quantity of radiation that ... far beyond what has been available, promising a ...
(Date:2/4/2016)... , Feb. 4, 2016 Wegener ... Global Markets Direct,s, ,Wegener Polyangiitis - Pipeline ... Wegener Polyangiitis,s therapeutic pipeline. This report provides ... Polyangiitis, complete with comparative analysis at various stages, ... (MoA), route of administration (RoA) and molecule type, ...
Breaking Medicine Technology: