Navigation Links
Prenatal exposure to pesticide additive linked with childhood cough
Date:9/5/2012

Children exposed in the womb to the widely used pesticide additive piperonyl butoxide (PBO) have heightened risk of noninfectious cough at ages 5 and 6, according to researchers at the Columbia Center for Children's Environmental Health (CCCEH) at the Mailman School of Public Health and of Columbia University Medical Center.

The findings, which appear in the August 31 online edition of the journal Environment International, support the premise that the children's respiratory system is susceptible to damage from toxic exposures during the prenatal period. A common symptom, childhood cough can disrupt normal daytime activities and interrupt sleep for both child and parent.

Piperonyl butoxide (PBO) is an organic compound used to bolster the effects of pyrethroid pesticides. Pyrethroids are the most commonly used pesticides for both professional pest control and non-professional residential use, according to a 2011 study by Mailman School researchers. Exposure to one pyrethroid, a variation of permethrin, was linked with increased risk for cough by age 5 in a 2009 study by Rachel Miller, MD. In the current study, Dr. Miller and colleagues sought to build on these findings by exploring the effects of subsequent exposure during childhood, looking specifically at the effects of PBO exposure.

Researchers looked at 224 mother-child pairs enrolled in the CCCEH birth cohort study of environmental exposures, examining measures of PBO and pyrethroid in personal air monitors worn by the mothers during pregnancy. Air samples also were collected from the home over the course of two weeks when children were between 5 and 6 years old. Questionnaires were used to evaluate respiratory outcomes.

Researchers found that children exposed to PBO during pregnancy had increased odds of reporting cough unrelated to cold or flu. Exposures to PBO during childhood were not a factor. There was no observed association between prenatal or childhood permethrin exposure and cough, something the researchers say may be explained by the fact that PBO is much easier to measure in air samples than permethrin. There was also no association with PBO or permethrin exposure and other respiratory outcomes like wheeze or asthma. While it is unclear whether the effect is due mainly to PBO itself or residential pyrethroids of which PBO is an indicator, it is important to remember, says Dr. Miller, that "these exposures may be a factor in a very common problem for childrencough."


'/>"/>

Contact: Timothy S. Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related medicine news :

1. Prenatal exposure to pollution especially dangerous for children with asthma
2. Prenatal exposure to common household chemical increases risk for childhood eczema, study says
3. Prenatal Exposure to Common Household Chemical Linked to Eczema
4. Prenatal maternal smoking associated with increased risk of adolescent obesity
5. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
6. Genetic variants, tobacco exposure and lung cancer risk
7. Leaded Gas Exposure Linked to Later Violence: Study
8. Majority of states fail to address youth exposure to alcohol marketing
9. Novel biomarkers reveal evidence of radiation exposure
10. Education May Protect Brain From Exposure to Solvents
11. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... Ill. (PRWEB) , ... December 07, 2016 , ... Levels ... early-stage brain damage, according to a study appearing online in the journal Radiology. , ... is expected to increase significantly due to the rapidly aging population. Damage to both ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... is now promoting to the US market its advanced highly customizable contact technology ... and ODU TURNTAC®. These advanced technologies are ideal for a wide range of ...
(Date:12/7/2016)... TX (PRWEB) , ... December 07, 2016 , ... ... offering insurance and financial planning services to families and business owners in the ... funds on behalf of the Dallas Fallen Officer Foundation. , Established in 2009 ...
(Date:12/7/2016)... ... , ... A. Kevin Spann Insurance, a New York-based firm offering insurance and ... a charity drive to raise funds that will benefit the Marine Corps League. , ... Navy FMF Corpsmen. Working closely with the MCL, the A. Kevin Spann team plans ...
(Date:12/7/2016)... , ... December 07, 2016 , ... ... to announce that its fully redesigned website, which launched October 17, 2016, features ... sleek responsive design and easy-to-navigate layout. Visitors and patients can discover the latest ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... India , December 7, 2016 According to ... (Services, Software), Delivery Mode, Product Type (Integrated, Standalone), Model (Knowledge-Based), Type (Therapeutic, ... MarketsandMarkets, The CDSS Market is expected to reach USD 1,519.2 Million by ... Continue Reading ... ...
(Date:12/7/2016)... , Dec. 7,2016  Based on ... delivery industry, Frost & Sullivan recognizes Nemaura ... & Sullivan Award for Enabling Technology Leadership. ... the loopholes in traditional drug delivery technologies, ... liquid microneedle-based drug delivery technologies, Memspatch and ...
(Date:12/7/2016)... Inc. (NASDAQ: IONS ), the leader in antisense therapeutics, ... BMO Capital Markets Prescriptions for Success Healthcare Conference on Wednesday, December ... A live webcast of the presentation will be available on the ... be available within 48 hours and will be archived for a ... , , ...
Breaking Medicine Technology: