Navigation Links
Prenatal exposure to endocrine-disrupting chemicals linked to breast cancer
Date:5/21/2010

A study in mice reveals that prenatal exposure to endocrine-disrupting chemicals, like bisphenol-A (BPA) and diethylstilbestrol (DES), may program a fetus for life. Therefore, adult women who were exposed prenatally to BPA or DES could be at increased risk of breast cancer, according to a new study accepted for publication in Hormones & Cancer, a journal of The Endocrine Society.

Endocrine-disrupting chemicals are substances in the environment that interfere with hormone biosynthesis, metabolism or action resulting in adverse developmental, reproductive, neurological and immune effects in both humans and wildlife. These chemicals are designed, produced and marketed largely for specific industrial purposes.

"BPA is a weak estrogen and DES is a strong estrogen, yet our study shows both have a profound effect on gene expression in the mammary gland (breast) throughout life," said Hugh Taylor, MD, of the Yale University School of Medicine in New Haven, Conn. and lead author of the study. "All estrogens, even 'weak' ones can alter the development of the breast and ultimately place adult women who were exposed to them prenatally at risk of breast cancer."

In this study, researchers treated pregnant mice with BPA or DES and then looked at the offspring as adults. When the offspring reached adulthood, their mammary glands still produced higher levels of EZH2, a protein that plays a role in the regulation of all genes. Higher EZH2 levels are associated with an increased risk of breast cancer in humans.

"We have demonstrated a novel mechanism by which endocrine-disrupting chemicals regulate developmental programming in the breast," said Taylor. "This study generates important safety concerns about exposures to environmental endocrine disruptors such as BPA and suggests a potential need to monitor women exposed to these chemicals for the development of breast lesions as adults."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Mount Sinai finds prenatal exposure to certain chemicals affects childhood neurodevelopment
2. Prenatal exposure to flame-retardant compounds affects neurodevelopment of young children
3. Good Parenting Triumphs Over Prenatal Stress
4. UM School of Medicine finds prenatal cocaine exposure not severely damaging to growth, learning
5. HAPPYBABY Unveils Partners Prenatal Instructional Yoga DVD
6. Prenatal Stress May Boost Babys Asthma Risk
7. Prenatal Healthcare Providers Inconsistent In Weight Gain Counseling
8. Exposure to prenatal smoking may lead to psychiatric problems
9. Babies Responses to Prenatal Stress Differ by Gender
10. Lead Exposure May Contribute to ADHD
11. NIH takes step to assess any possible risk associated with low-dose radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... 2014 This September, California Library ... Library, celebrates 30 years of changing the lives ... inception, California’s Library Literacy Services has helped nearly ... read and write. , To mark the 30th ... is launching a month-long awareness campaign titled “Together, ...
(Date:8/31/2014)... August 2014: Renal denervation seems to be more successful ... when it includes accessory renal arteries, according to research ... from Germany. , Dr Schmiedel said: "More than one ... defined as blood pressure (BP) greater than 140/90 mmHg. ... (rHTN) and are unable to reduce BP below 140/90 ...
(Date:8/30/2014)... A new method to predict the optimal number ... at ESC Congress today by Dr Benjamin Dahan from ... AEDs located in public places for optimal prevention of ... said: "Out of hospital cardiac arrest is a major ... 50 and 100 per 100 000 in the general ...
(Date:8/30/2014)... Walking-Canes.Net has released several articles related ... can help in making gait problems easier. The new ... website that contains all of the news articles that were ... articles deal with diseases that make walking a problem and ... help in making life easier for the patient. The articles ...
(Date:8/30/2014)... As the economy continues to recover and ... bathrooms and in-home fitness centers, the North American ... interest not only in designing and installing saunas but ... of sauna. Through working with manufacturers across North ... Society provides a strong knowledge base of Finnish traditions ...
Breaking Medicine News(10 mins):Health News:California Library Literacy Services Celebrates 30th Anniversary 2Health News:California Library Literacy Services Celebrates 30th Anniversary 3Health News:Renal denervation more successful when it includes accessory arteries 2Health News:New method predicts optimal number and location of AEDs 2Health News:Information Articles on Gait Problems from Walking-Canes.Net 2Health News:As Interest in Saunas Increases, the North American Sauna Society Increases Outreach to Provide Education on History, Design, and Culture 2
... , , Consumers Must Have Full ... by Congress , , WASHINGTON, Sept. 22 ... the National Association of Professional Insurance Agents (PIA) is again reminding ... of licensed, professional, independent insurance agents in any reform plan devised ...
... SAN DIEGO, Sept. 22 US Farms, Inc. (Pink Sheets: ... Inc., a Southern California based branding and interactive marketing firm to assist ... consumer brand product line, Aloe365. , , Yan ... are now in a full blown sales and marketing effort with our ...
... 22 /PRNewswire-Asia/ -- The Yanda International Health,City is set to ... The environmentally friendly complex will include facilities offering,state-of-the-art care for ... medical research and training facilities. It,will also include an international ... a model in healthcare services in the 21st century. It ...
... , , , ... rates of childhood obesity and related diseases could mean the next generation ... their parents, NFL Network today kicked off the second year of ... on Manhattan,s Lower East Side. As part of the league,s NFL ...
... NEW YORK, Sept. 22 Reportlinker.com announces that a ... , U.S. Equine Market: Feed, Health Care ... http://www.reportlinker.com/p0148037/US-Equine-Market-Feed-Health-Care-and-Services-for-Horses-The.html , , ... States, which are used primarily for recreation and entertainment. These horses ...
... , , DUBLIN, ... an expanded suite of consulting, analytics and operations services to ... patient safety. , , These ... their hospitals address ongoing economic constraints, improve quality outcomes and ...
Cached Medicine News:Health News:Healthcare Reform Must Include Full Participation by Licensed Professional Insurance Agents 2Health News:US Farms, Inc. Announces Agreement With Rage Marketing, Inc. to Increase Brand Awareness and E-Commerce Product Sales 2Health News:US Farms, Inc. Announces Agreement With Rage Marketing, Inc. to Increase Brand Awareness and E-Commerce Product Sales 3Health News:Yanda International Health City - World Class Healthcare in China 2Health News:Yanda International Health City - World Class Healthcare in China 3Health News:NFL Network Launches 2009 National Keep Gym in School Campaign at New York City Middle School; Effort Will Give More U.S. Students Access to Quality Physical Education 2Health News:NFL Network Launches 2009 National Keep Gym in School Campaign at New York City Middle School; Effort Will Give More U.S. Students Access to Quality Physical Education 3Health News:NFL Network Launches 2009 National Keep Gym in School Campaign at New York City Middle School; Effort Will Give More U.S. Students Access to Quality Physical Education 4Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 2Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 3Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 4Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 5Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 6Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 7Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 8Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 9Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 10Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 11Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 12Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 13Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 14Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 15Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 16Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 17Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 18Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 19Health News:Reportlinker Adds U.S. Equine Market: Feed, Health Care and Services for Horses, The Report 20Health News:Cardinal Health Introduces Expanded Suite of Services to Help Hospital Pharmacies Improve Cost Containment, Workflow, Patient Safety 2Health News:Cardinal Health Introduces Expanded Suite of Services to Help Hospital Pharmacies Improve Cost Containment, Workflow, Patient Safety 3Health News:Cardinal Health Introduces Expanded Suite of Services to Help Hospital Pharmacies Improve Cost Containment, Workflow, Patient Safety 4
(Date:8/29/2014)... , Aug. 29, 2014 Research ... "Global Multiple Sclerosis Drugs Market 2014-2018" report ... a chronic, inflammatory medical condition that results in demyelination, ... because of an abnormal response by the immune system, ... It is a potentially debilitating disease in which the ...
(Date:8/29/2014)... MENLO PARK, Calif. , Aug. 29, ... (OTCQB: DMPI) ("DelMar" "the Company") today announced the filing ... Company recently changed its fiscal year end to June ... its common stock on a national securities exchange in ... as filed with the United States Securities Exchange Commission ...
(Date:8/29/2014)... ANDOVER, Mass. , Aug. ...  (NYSE: PHG ... at the  European Society of ... company is highlighting the full range of its cardiology solutions ... the care continuum from prevention and ...
Breaking Medicine Technology:Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 2Global Multiple Sclerosis Drugs Market 2014-2018: Key Vendors are Bayer, Biogen Idec, Merck Serono, Novartis and Teva Pharmaceutical 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 2DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 3DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 4DelMar Pharmaceuticals Fiscal 2014 Year End Results and Summary of Recent Developments 5Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 2Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 4Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 5
... Life Spine, a medical device company that designs, ... of spine disorders, announced that on Saturday, April 2, ... Technology Training. Over twenty surgical participants ... hands-on cadaver lab training on the safe and effective ...
... Smith & Nephew,s (NYSE: SNN ; ... System, an operative hysteroscopy device for the removal of ... milestone. The TRUCLEAR System is a first-of-its ... hysteroscope with minimally invasive tissue removal capabilities, allowing a ...
Cached Medicine Technology:Smith & Nephew's TRUCLEAR System: A Gold Standard for Removal of Intrauterine Polyps and Fibroids 2Smith & Nephew's TRUCLEAR System: A Gold Standard for Removal of Intrauterine Polyps and Fibroids 3Smith & Nephew's TRUCLEAR System: A Gold Standard for Removal of Intrauterine Polyps and Fibroids 4
Weitlaner retractor, blunt....
Halle bone curette, 8 1/4, oval, malleable shaft, 4 mm wide....
Bruns (Volkmann) bone curette, with Novotex plastic handle (autoclavable in autoclave up to 143C by 3 bar), 9, oval....
Ring curette, 4 mm 90 angle....
Medicine Products: