Navigation Links
Prenatal exposure to common household chemical increases risk for childhood eczema, study says
Date:6/25/2012

Prenatal exposure to a ubiquitous household chemical called butylbenzyl phthalate (BBzP) can increase a child's risk for developing eczema, according to research conducted at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health.

Widely used in vinyl flooring, artificial leather and other materials, BBzB can be slowly released into air in homes.

Details are published in the advance online edition of Environmental Health Perspectives, a journal of the National Institute of Environmental Health Sciences.

Eczema, which is characterized by dry, itchy red skin on the face, scalp, or extremities, is common in early childhood. "While hereditary factors, allergens, and exposure to tobacco smoke are known to contribute to the condition, our study is the first to show that prenatal exposure to BBzB is a risk factor," says Allan C. Just, PhD, first author on the Mailman School study and currently a postdoctoral researcher at the Harvard School of Public Health.

The study looked at 407 nonsmoking African-American and Dominican women and their children in New York City. Exposure to BBzB was measured through a urine test during the third trimester of pregnancy. Following birth, the mothers were asked if their child had been diagnosed with eczema. The result: onset of eczema by age 2 was 52 percent more likely in children whose mothers had been exposed to higher concentrations of BBzP, compared with those whose mothers had been exposed to lower concentrations. All but one of the women in the study showed some level of exposure to the chemical.

How BBzP might induce eczema remains murky. To explore that question, the researchers looked at allergies as a possible mechanism. Children were tested for three common indoor allergens: cockroaches, dust mites, and mice, as well as for total IgE, a biomarker for an immune response to all allergens. But they found no evidence of a link between BBzP exposure and allergy.

"We know allergies are a factor with some childhood eczema, but our data suggest that is not the case when BBzP is involved," says senior author Rachel Miller, MD, Director of the Allergy and Immunology fellowship program and Associate Professor of Medicine (in Pediatrics) and Environmental Health Sciences, NewYork-Presbyterian Hospital/Columbia University Medical Center; and a Co-Deputy Director of the Columbia Center for Children's Environmental Health. "However, these are important findings, given that eczema is a common and uncomfortable disease of early childhood."

The researchers also found that while African-American mothers in the study were twice as likely as their Dominican-American counterparts to report that their child had been diagnosed with eczema, both groups had a similar association between BBzP exposure and the disease.

Previous research by study co-author Robin M. Whyatt, DrPH, Professor of Clinical Environmental Health Sciences and Co-Deputy Director of the Columbia Center for Children's Environmental Health, found that exposure to BBzP and other phthalates was shown to delay motor skill development in young children and to increase risk for behavioral problems. Phthalates are also known to disrupt the body's endocrine system.


'/>"/>
Contact: Timothy S. Paul
tp2111@columbia.edu
212-305-2676
Columbia University's Mailman School of Public Health
Source:Eurekalert

Related medicine news :

1. Prenatal exposure to pollution especially dangerous for children with asthma
2. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
3. Genetic variants, tobacco exposure and lung cancer risk
4. Leaded Gas Exposure Linked to Later Violence: Study
5. Majority of states fail to address youth exposure to alcohol marketing
6. Novel biomarkers reveal evidence of radiation exposure
7. Education May Protect Brain From Exposure to Solvents
8. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
9. New research showing how real-life exposure to violence disrupts a childs sleep habits
10. BPA exposure effects may last for generations
11. How MyTownInsurance.com Helps Insurance Carriers Manage their Loss Exposure through On-Line Marketing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the ... published author, William Nowers. Captain Nowers and his wife, Millie, have six children, ... in the Navy. Following his career as a naval aviator and carrier pilot, ...
(Date:10/12/2017)... ... 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one of the ... new design of the shoulder pad. The shoulder pad provides optimal support and ... pain while using cold therapy. By utilizing ice and water that is circulated from ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... HMP ... the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare ... City on October 11, 2017. , The annual award competition recognizes editorial and design ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in property taxes a year. In some states—like New York, New Jersey, Massachusetts, ... contrast, many overseas retirement havens have extremely low property-tax rates, which contributes to ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  Caris Life Sciences ® , ... the promise of precision medicine, today announced that St. ... Precision Oncology Alliance™ (POA) as its 17 th ... St. Jude Crosson Cancer Institute will help develop standards ... of tumor profiling, making cancer treatment more precise and ...
(Date:10/10/2017)... EXTON, Pa. , Oct. 10, 2017   ... leader in innovative solutions for injectable drug administration, today ... of West,s ID Adapter for improving the intradermal administration ... the Fourth Skin Vaccination Summit in May 2017 by ... Team Lead, Polio Department, World Health Organization (WHO), and ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017  According to the Centers for ... the end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the ... as mandated by certain health insurance regulations. ... The best time to get a flu shot is by the ...
Breaking Medicine Technology: