Navigation Links
Prenatal exposure to combustion-related pollutants and anxiety, attention problems in young children

NEW YORK ( March 22, 2012) - Mothers' exposure during pregnancy to a class of air pollutants called polycyclic aromatic hydrocarbons (PAH) can lead to behavioral problems in their children. PAH are released to air during incomplete combustion of fossil fuel such as diesel, gasoline, coal, and other organic material.

The study is the first report of associations between child attentional and behavioral problems among school‐age children and two complementary measures of prenatal PAH exposure: monitored air concentrations of PAH and a PAH-specific biomarker of exposure measured in maternal and umbilical cord blood. The paper, "Prenatal Polycyclic Aromatic Hydrocarbon (PAH) Exposure and Child Behavior at age 6-7," published online today in Environmental Health Perspectives, adds to rising concerns about the risks associated with exposures to air pollution during pregnancy.

The study followed the children of 253 non‐smoking inner-city women who gave birth between 1999 and 2006. Researchers led by Frederica Perera, DrPH, director of the Columbia Center for Children's Environmental Health at the Mailman School of Public Health, measured two complementary indicators of PAH exposure. One indicator was the PAH concentration in air from personal air sampling which took place during the third trimester of pregnancy. The other was a specific biological marker of exposure-- PAHDNA adducts measured in maternal blood and newborn umbilical cord blood. When inhaled by the mother during pregnancy, PAH can be transferred across the placenta and bind to the DNA of the fetus, forming "adducts" in blood and other tissues and providing a biologic measure of pollutant exposure.

Mothers completed a detailed assessment of their child's behavior (including whether the children experienced symptoms of anxiety, depression, or attention problems. High prenatal PAH exposure, whether characterized by personal air monitoring or maternal and newborn cord adducts, was significantly associated with symptoms of Anxious/Depressed and Attention Problems.

In urban air, traffic emissions are a dominant source of the pollutants measured in the study. Illustrating widespread exposure to these pollutants, 100% of the mothers in the Columbia Center for Children's Environmental Health NYC cohort had detectable levels of PAH in prenatal personal air samples, although levels varied widely. The authors accounted for other sources of PAH such as environmental tobacco smoke and diet in their analyses. None of the mothers in the study were smokers.

"This study provides evidence that environmental levels of PAH encountered in NYC air can adversely affect child behavior. The results are of concern because attention problems and anxiety and depression have been shown to affect peer relationships and academic performance," said Dr. Perera, the study's lead author.


Contact: Stephanie Berger
Columbia University's Mailman School of Public Health

Related medicine news :

1. Good Parenting Triumphs Over Prenatal Stress
2. UM School of Medicine finds prenatal cocaine exposure not severely damaging to growth, learning
3. HAPPYBABY Unveils Partners Prenatal Instructional Yoga DVD
4. Prenatal Stress May Boost Babys Asthma Risk
5. Prenatal Healthcare Providers Inconsistent In Weight Gain Counseling
6. Exposure to prenatal smoking may lead to psychiatric problems
7. Babies Responses to Prenatal Stress Differ by Gender
8. Prenatal exposure to endocrine-disrupting chemicals linked to breast cancer
9. Prenatal Exposure to Chemicals Linked to Breast Cancer Risk
10. Prenatal Pesticide Exposure May Raise Risk of Attention Issues in Kids
11. Prenatal Exposure to Pesticides May Harm Kids Development
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... A novel class ... could be effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major ... showed that small molecule analogs that target the functions of SecA, a central ...
(Date:11/30/2015)... ... , ... Using a combination of two blood sugar tests rather than a ... a new study by researchers at the School of Public Health at Georgia State ... of Blood Glucose Tests ,” published in Frontiers in Public Health, the researchers noted ...
(Date:11/30/2015)... ... November 30, 2015 , ... International telepathology ... UPMC and KingMed Diagnostics researchers. Their review of more than ... with UPMC pathologists resulted in significantly altered treatment plans for more than half ...
(Date:11/30/2015)... ... November 30, 2015 , ... The Foundation for Breast and ... prevention—is joining forces with the award-winning creator and writer of Downton Abbey Julian ... 2015 at the Union League of Philadelphia. , The benefit, titled “An ...
(Date:11/30/2015)... ... November 30, 2015 , ... California-based i2i ... years, announced today that Michigan-based Family Health Center (FHC) has selected i2iTracks as ... years, FHC was awarded the largest Affordable Care Act grant for Federally Qualified ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Nov. 30, 2015 Booth #4303 – The Imaging ... will exhibit a broader array of products in a new ... of North America in ... meeting will feature X-ray components "At the Heart of Imaging." ... of products from Varian,s Claymount brand, and computer-aided diagnostic software ...
(Date:11/30/2015)... EAST HANOVER, N.J. , Nov. 30, 2015 /PRNewswire/ ... and portfolio at the 57 th American Society ... across leukemias, lymphomas and myelomas as well as supportive ... populations, in addition to personalized cell therapies. The ASH ... Orlando, Florida . Novartis Oncology ...
(Date:11/30/2015)... LONDON and BOSTON , ... to research and develop potential new medicines directed at ... multiple therapeutic areas. --> PFE ) to ... to 10 G protein-coupled receptor (GPCR) targets across multiple ... clinical-stage GPCR structure-guided drug discovery and development company and ...
Breaking Medicine Technology: