Navigation Links
Preliminary Data From Pitt County Memorial Hospital Study Show Benefit of Active Surveillance on Reducing MRSA VAP Rates in Surgical ICU

GREENVILLE, N.C., April 6, 2008 /PRNewswire/ -- Pitt County Memorial Hospital (PCMH) today announced preliminary data suggesting a statistically significant reduction in the rate of ventilator-associated pneumonia (VAP) due to methicillin-resistant Staphylococcus aureus (MRSA) in the surgical intensive care unit (SICU) with the implementation of an active surveillance program for MRSA. These data were presented today as a poster at the Society for Healthcare Epidemiology of America's (SHEA) 18th Scientific Annual Meeting in Orlando, FL by Titu Das, M.D., MPH, Fellow, Infectious Disease Division, The Brody School of Medicine at East Carolina University. Further analysis of these data will be submitted to a medical journal for peer review.

Led by Keith Ramsey, M.D., Medical Director for Infection Control at PCMH, and Professor of Medicine at the Brody School of Medicine at East Carolina University, the study is the first and only that we are aware of to specifically look at VAP reduction in the SICU using a targeted active surveillance program.

During the 12-month intervention period, MRSA VAP rates in the SICU decreased by 68 percent due to the implementation of a comprehensive infection control program that included hospital-wide (universal) active surveillance using the BD GeneOhm(TM) MRSA real-time polymerase chain reaction (PCR) diagnostic test. The analysis of the SICU-specific data shows that the MRSA VAP rate decreased from 1.74 to 0.54 per 1,000 ventilator days.

"We were seeing an upward trend in the number of patients coming to the hospital with MRSA and we wanted to prevent transmission in our hospital," said Dr. Ramsey. "At our facility, active surveillance of patient admissions using PCR testing, combined with immediate isolation of MRSA carriers and eradication treatment with topical antibiotics, helped to significantly reduce our VAP MRSA rate in the SICU. We have not seen any VAPs since June 2007 in our SICU."

MRSA is an important cause of VAP in the ICU, and can cause longer hospital stays and a high mortality rate. According to a study published in the American Journal of Respiratory Critical Care Medicine, the mortality rate for VAP ranges from 24 percent to 50 percent and can reach 76 percent in some settings or when lung infection is caused by high-risk pathogens. ICU ventilated patients with VAP have been reported to have a two- to 10-fold higher risk of death compared with patients without pneumonia. In addition to having a high mortality rate, MRSA VAP is also associated with an increased utilization of resources, including longer ventilator dependence and excess costs of approximately $8,000.

In a separate study comparing VAP due to MRSA or methicillin-sensitive Staphylococcus aureus (MSSA), mortality was found to be directly attributable to pneumonia for 86 percent of the MRSA patients and 12 percent in the MSSA patients, with a relative risk of death equal to 20.7 for MRSA pneumonia.

These study results add to a growing body of data released over the past few years demonstrating the impact of active patient surveillance for MRSA, coupled with a comprehensive infection prevention program to reduce MRSA infections.

MRSA bacteria can cause a potentially fatal infection that does not respond to commonly used antibiotics and is a significant cause of healthcare- associated infections. The Centers for Disease Control and Prevention estimate that approximately 126,000 people are hospitalized each year with MRSA infections and about 19,000 die, with an estimated annual cost of $3.2 billion to $4.2 billion to U.S. hospitals.

PCMH, located in Greenville, NC, serves a rural population in 29 counties. The SICU-data represent a subset of a wider study conducted by PCMH over the past year, which looks at the impact of a hospital-wide, all-admission surveillance, the data for which is being compiled for future release.

About Pitt County Memorial Hospital

Pitt County Memorial Hospital, one of four academic medical centers in North Carolina, is the flagship hospital for University Health Systems of Eastern Carolina and serves as the teaching hospital for the Brody School of Medicine at East Carolina University. Pitt Memorial is a regional resource for all levels of health services and information.

The hospital is a tertiary referral center and provides acute, intermediate, rehabilitation and outpatient health services to more than 1.2 million people in 29 counties. In an average year, about 33,000 inpatients and more than 266,000 outpatients are treated in our facilities. More than 3,000 babies are born here in a typical year. The clinical staff includes more than 500 physicians and 1,200 nurses.


Barbara Dunn Trish Gannon

Pitt County Memorial Hospital Manning, Selvage & Lee

Phone: (252) 847-7599 Phone: (617) 937-2566

Email: Email:

SOURCE Pitt County Memorial Hospital
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. NBTY Announces Preliminary Unaudited Net Sales Results For August 2007
2. Wyeth and Nycomed Announce Court Denial of Preliminary Injunction
3. Paramount Acquisition Corp. Files Amendment to Preliminary Proxy Statement for Proposed Acquisition of Chem Rx
4. Volcano Corporation Reports Preliminary Third Quarter 2007 Revenues
5. NBTY Announces Preliminary Unaudited Net Sales Results
6. Aspreva Announces Preliminary Revenues for Third Quarter 2007
7. WebMD Reports Preliminary Third Quarter Financial Results
8. The Organic Trade Association Hails Preliminary Research Findings Showing Nutritional Benefits of Organic Products
9. Sunrise Reports Preliminary Selected Financial and Operating Data for Third-Quarter 2007
10. MedQuist Files Preliminary Proxy Statement and Applies for Listing on NASDAQ
11. MIGENIX Reports Preliminary Celgosivir Viral Kinetics Study
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now ... of Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Final Cut Pro X users can now reveal the media of their split ...
(Date:6/27/2016)... ... 27, 2016 , ... A revolution is underway. Brooklyn-based ... experience for the millions of people who require these medical transport services annually. ... through the use of technology. Now, SmartEMS has put forth an industry-changing app ...
(Date:6/26/2016)... , ... June 26, 2016 , ... On June 10-11, ... of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, ... the city’s history as home to some of the world’s leading providers of cereal ...
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer ... through a fitness app. The fitness app plans to fix the two major problems leading ... a one size fits all type program , They don’t eliminate all the ...
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/23/2016)... Calif. , June 23, 2016 Any dentist ... many challenges of the current process. Many of them do ... of the technical difficulties and high laboratory costs involved. And ... to offer it at such a high cost that the ... it. Dr. Parsa Zadeh , founder of ...
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
Breaking Medicine Technology: