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Preliminary Data From Pitt County Memorial Hospital Study Show Benefit of Active Surveillance on Reducing MRSA VAP Rates in Surgical ICU
Date:4/6/2008

GREENVILLE, N.C., April 6, 2008 /PRNewswire/ -- Pitt County Memorial Hospital (PCMH) today announced preliminary data suggesting a statistically significant reduction in the rate of ventilator-associated pneumonia (VAP) due to methicillin-resistant Staphylococcus aureus (MRSA) in the surgical intensive care unit (SICU) with the implementation of an active surveillance program for MRSA. These data were presented today as a poster at the Society for Healthcare Epidemiology of America's (SHEA) 18th Scientific Annual Meeting in Orlando, FL by Titu Das, M.D., MPH, Fellow, Infectious Disease Division, The Brody School of Medicine at East Carolina University. Further analysis of these data will be submitted to a medical journal for peer review.

Led by Keith Ramsey, M.D., Medical Director for Infection Control at PCMH, and Professor of Medicine at the Brody School of Medicine at East Carolina University, the study is the first and only that we are aware of to specifically look at VAP reduction in the SICU using a targeted active surveillance program.

During the 12-month intervention period, MRSA VAP rates in the SICU decreased by 68 percent due to the implementation of a comprehensive infection control program that included hospital-wide (universal) active surveillance using the BD GeneOhm(TM) MRSA real-time polymerase chain reaction (PCR) diagnostic test. The analysis of the SICU-specific data shows that the MRSA VAP rate decreased from 1.74 to 0.54 per 1,000 ventilator days.

"We were seeing an upward trend in the number of patients coming to the hospital with MRSA and we wanted to prevent transmission in our hospital," said Dr. Ramsey. "At our facility, active surveillance of patient admissions using PCR testing, combined with immediate isolation of MRSA carriers and eradication treatment with topical antibiotics, helped to significantly reduce our VAP MRSA rate in the SICU. We have not seen any VAPs since June 2007 in our SICU."

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SOURCE Pitt County Memorial Hospital
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