Navigation Links
Preemies' Low Blood Pressure Linked to SIDS
Date:12/1/2008

Preterm infants already at higher risk for SIDS and this may be why, researchers say

MONDAY, Dec. 1 (HealthDay News) -- Premature infants often have lower-than-normal blood pressure that persists during the first six months of life and may be one reason these infants are more prone to sudden infant death syndrome (SIDS), Australian researchers suggest.

One theory of the cause of SIDS is a profound drop in blood pressure during sleep, from which the infant cannot recover.

"Premature babies are at increased risk for SIDS, and we investigated a possible mechanism of how these babies could be at increased risk," explained lead researcher Rosemary S.C. Horne, of the Ritchie Centre for Baby Health Research at the Monash Institute of Medical Research at Monash University in Melbourne.

For the study, Horne's team monitored the heart rates of 25 premature infants, comparing them with 20 infants born at term. The researchers looked at the infants' blood pressure at two to four weeks, two to three months, and five to six months.

They found that preterm infants had lower blood pressure during sleep compared with normal-term infants. This was true during all the periods the blood pressure was measured.

Systolic blood pressures in preterm infants were 11 mm Hg to 14 mm Hg lower than in full-term infants, Horne said. "This may be clinically significant," she noted.

"We hypothesize that if blood pressure is already low in preterm babies, then if there was an event during sleep that made it fall even further they may be at risk of a profound drop in blood pressure," Horne said.

"In addition, this may explain the risk of preterm babies having an increased risk of SIDS and it may also indicate that these preterm babies, although they appear well and healthy, may have long-term alterations in their cardiovascular control," she said.

The findings were published in the December issue of Pediatrics.

Dr. Warren G. Guntheroth, a professor of pediatrics at the University of Washington School of Medicine in Seattle, doesn't think low blood pressure is a cause of SIDS. He believes the trouble lies with breathing problems.

"I do not believe there is enough evidence that control of blood pressure is inadequate just because the systolic pressure in preemies is lower than average," Guntheroth said. "This may well be because they are small."

Preemies do have pulmonary problems, of course, and it's likely that this accounts for an increase in SIDS, Guntheroth said. "The pulmonary problems may induce a degree of low oxygen that can increase the frequency of apnea with bradycardia, but that is a very basic response that does not indicate an immaturity of control of the cardiovascular system," he said.

Another SIDS expert also said it's not known whether low blood pressure increases the risk of SIDS.

"The unresolved question is whether these differences in blood pressure have any relevance for the increased risk for SIDS that preterms have -- that's unclear," said Dr. Carl E. Hunt, an adjunct professor of pediatrics at the Uniformed Services University of the Health Sciences, in Bethesda, Md.

"The extent to which the inability to recover normal blood pressure is a precipitating event for SIDS, we have no idea," said Hunt, who's also a director at the American SIDS Institute. "It's difficult to prove and it has not been proven."

More information

For more on SIDS, visit the U.S. National Library of Medicine.



SOURCES: Rosemary S.C. Horne, Ph.D., Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia; Warren G. Guntheroth, M.D., professor, pediatrics, University of Washington School of Medicine, Seattle; Carl E. Hunt, M.D., adjunct professor, pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Md., and member, board of directors, American SIDS Institute; December 2008 Pediatrics


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Caffeine Therapy Boosts Preemies Outcomes
2. Tel Aviv University gives preemies a fighting chance
3. Epsom Salt Cut Cerebral Palsy Rate in Half Among Preemies
4. Steroid treatment offers no benefit in preemies, Hopkins Childrens study suggests
5. Drugs to Treat Lung Damage in Preemies May Harm Brain
6. Specific antagonism lowers blood pressure
7. Restricting Blood Flow May Help Heart Bypass Patients
8. FDA Updates Prescription Guidelines for Blood Thinner
9. Doctors Often Miss High Blood Pressure in Kids
10. Back to School Means Return of School Blood Drives
11. Blood-flow detector software show promise in preventing brain damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... ... initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the advanced skills needed to introduce ... from U.S. universities who will draw from Siemens’ deep knowledge of product ...
(Date:2/12/2016)... ... ... Each year, the American Physical Therapy Association (APTA) offers a Combined Sections Meeting. ... Almost 10,000 physical therapists across the country are expected to attend this annual convention ... field and network with their colleagues. As in years past, HydroWorx is proud ...
(Date:2/12/2016)... ... February 12, 2016 , ... The ... Zuckerberg San Francisco General Hospital on April 5-7. The series is a multi-day, ... new habits. The workshops cover a broad range of topics, including coaching skills, ...
(Date:2/12/2016)... ... , ... AssureVest Insurance Group, a locally owned insurance firm with offices serving ... funds earmarked to purchase computers and software for Mrs. Harrison’s 2nd and 3rd grade ... a low-income area and has more than 60 2nd and 3rd graders with learning ...
(Date:2/12/2016)... , ... February 12, 2016 , ... ... the Pittsburgh metro area, celebrates the beginning of the latest charity campaign in ... social skills through art. Donations to this worthy cause are currently being accepted ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... The primary goal of this research is to analyze ... of liquid biopsy. Key information the survey seeks to ... liquid biopsy adoption amidst future users - Predominantly used ... Sample inflow to conduct liquid biopsy tests - Preference ... on. - Correlation analysis of sample type and biomarker ...
(Date:2/11/2016)... PRO-DEX, INC. (NasdaqCM: PDEX) today announced financial results for its ... also filed its Quarterly Report on Form 10-Q for the ... Exchange Commission today. --> --> ... --> Net sales for the three months ... $5.4 million from $2.8 million for the three months ended ...
(Date:2/11/2016)... 2016  Kindred Biosciences, Inc. (NASDAQ: KIN ), ... lives of pets, today announced the submission to FDA ... Drug Application (NADA) for Zimeta™ (dipyrone injection, KIND-012).  Positive ... Zimeta for the control of pyrexia (fever) in horses ... --> --> The Chemistry, Manufacturing, and ...
Breaking Medicine Technology: