Navigation Links
Preemies Exposed to Toxins in Liquid Meds
Date:1/23/2009

Called excipients, these agents include chemicals that can cause nerve damage, study says

FRIDAY, Jan. 23 (HealthDay News) -- Potentially harmful agents called excipients are contained in liquid medicines commonly given to premature infants, according to a U.K. study.

Excipients are used to ease the administration, absorption or preservation of the active substances or to improve the taste and appearance of the liquid medicines, according to background information in the study.

The British researchers assessed the type and content of liquid medicines given to 38 premature babies in a neonatal intensive care unit. The babies were treated for between 2.5 weeks and nine weeks and given a range of treatments, including iron, vitamin drops, furosemide and fexamethasone.

During their treatment, the infants were regularly exposed to 20 different excipients, including ethanol (found in iron and furosemide) and propylene glycol (found in dexamethasone). These chemicals can cause nerve damage.

The infants' exposure to ethanol ranged from 0.2 ml to 1.8 ml a week, equivalent to one to seven units of alcohol, while exposure to sorbitol (dexamethasone and iron) ranged from 0.1 to 3.5 g/week. The recommended maximum intake of sorbitol for adults is 20 g/day. When calculated by weight, this level was exceeded in 18 babies for at least one week. The study also found that all babies given dexamethasone exceeded the recommended levels of propylene glycol, which is about two-thirds the strength of ethanol.

The seven infants with severe lung disease were exposed to higher levels of excipients than the other premature babies.

The findings were published in the Fetal & Neonatal Editions of Archives of Disease in Childhood.

It's difficult for makers of children's medicines to tailor their products for each age group, and the use of some excipients is necessary, the study authors noted. However, they concluded: "We feel it is important that the [medicines regulators] not only ensure that all manufacturers provide detailed labeling of the excipient content of their products but all lead action to determine whether existing practice constitutes a risk, and if so, how this might be dealt with."

More information

The U.S. National Institute of Child Health and Human Development has more about preterm labor and birth.



-- Robert Preidt



SOURCE: BMJ specialist journals, news release, Jan. 20, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Sepsis Therapy in Preemies Fails to Boost Survival
2. Multiple Doses of Steroids Dont Help Preemies
3. Preemies Low Blood Pressure Linked to SIDS
4. Drugs to Treat Lung Damage in Preemies May Harm Brain
5. Steroid treatment offers no benefit in preemies, Hopkins Childrens study suggests
6. Epsom Salt Cut Cerebral Palsy Rate in Half Among Preemies
7. Tel Aviv University gives preemies a fighting chance
8. Caffeine Therapy Boosts Preemies Outcomes
9. Recovery coaches effective in reducing number of babies exposed to drugs
10. Almost Half of Kids Still Exposed to Secondhand Smoke
11. Newborns exposed to maternal smoking more irritable, difficult to soothe
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Preemies Exposed to Toxins in Liquid Meds
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... ... , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys ... peers for this recognition are considered among the top 2 percent of lawyers practicing ... members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief ... a minimum wage raise to $12 an hour by 2020 and then adjusting it yearly ... lost value of the minimum wage, assure the wage floor does not erode again, and ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... ... Haute Living, is proud to recognize Dr. Barry M. Weintraub as a prominent ... “the most beautiful women in the world, and the most handsome men, look ...
(Date:6/24/2016)... ... ... National recruitment firm Slone Partners is pleased to announce the placement of ... President of North American Capital Sales at HTG Molecular . , ... the commercialization of the HTG EdgeSeq system and associated reagents in North America. , ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
Breaking Medicine Technology: