Navigation Links
Prednisolone not benficial in most cases of community-acquired pneumonia
Date:2/23/2010

Patients hospitalized with mild to moderate community-acquired pneumonia (CAP) should not be routinely prescribed prednisolone, a corticosteroid, as it is associated with a recurrence of symptoms after its withdrawal, according to the first randomized double-blind clinical trial to address the subject.

"Prednisolone therapy next to antibiotic therapy in patients hospitalized with CAP should not be recommend due to lack of clincial benefit and a higher rate of late failures," said Dominic Snijders, M.D., lead author on the study and at the Medical Centre Alkmaar in the Netherlands.

The findings have been published online ahead of print publication in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

To assess the efficacy of prednisolone therapy along with standard doctor-managed care for patients admitted to the hospital with CAP, Dr. Snijders and colleagues prospectively enrolled 213 patients who had been hospitalized with CAP and randomly assigned them to receive the usual antibiotic therapy as prescribed by their physicians supplemented with either prednisolone (40 mg dose once daily) or placebo for a week.

They found that patients on prednisolone recovered more rapidly from their fevers and had a more rapid decline in their c-reactive protein (CRP) levels than patients on placebo, indicating decreased inflammation. However, after 14 days, the patients in the prednisolone group had higher levels of CRP than the patients in the placebo group. Furthermore, three times as many patients in the prednisolone group had "late failure," defined as the recurrence of symptoms more than 72 hours after initial therapeutic success, and these patients were almost four times as likely to require additional antibiotic treatment than patients with late failure in the placebo group (6.7 percent versus 1.8 percent).

"Our study clearly shows that prednisolone therapy does not have a
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-315-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2

Related medicine news :

1. RAND finds cases of undiagnosed diabetes drop sharply
2. South Texas Doctors Report More Severe Cases of Community Staph Super Bug Hospitalizing Children
3. Gene profiling can single out the worst cases of multiple myeloma and guide therapy
4. Peer-Reviewed, Online Database Showcases Local, County and State Pandemic Planning
5. HIV/AIDS Cases Among State and Federal Prison Inmates Fell for the Sixth Straight Year During 2005
6. Surge in U.S. Cases of Rocky Mountain Spotted Fever
7. The era of global aging: GSA showcases cutting-edge San Francisco meeting topics
8. Capsule endoscopy turning up undiagnosed cases of Crohns disease
9. BancTec Showcases Accounts Payable and Healthcare Solutions at The Association for Financial Professionals (AFP) Annual Conference
10. Stereotaxis Showcases Interventional Cardiology Capabilities of Niobe Magnetic Navigation System
11. Stereotaxis Highlights Live Coronary and Peripheral Vascular Cases Performed at TCT With Stereotaxis Magnetic Navigation System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Recently, iFitDress.com, one of the most famous dress suppliers ... evening gown collection. According to the company’s sales manager, ... (up to 69% off) at present. Additionally, all the company’s ... am a frequent caller of your site. I like your ... feel quite happy. All items are of good quality. I ...
(Date:9/16/2014)... Today, Top10BestSEOHosting.com compares many professional Windows ... announces that HostMonster, Arvixe and GreenGeeks.com ( ... hosting companies in the market. These companies ... WordPress hosting (including VPS and cloud hosting) ... outstanding customer support and a number of ...
(Date:9/16/2014)... September 16, 2014 Paradigm Physical Therapy ... a new therapeutic treatment for their patients. Dry needling ... treat a variety of musculoskeletal problems. , In this ... inserted into the skin and muscle to create a ... needle, the needle helps to deactivate and release the ...
(Date:9/16/2014)... Cliff Lake Dental Care is proud to announce the ... hygienist to join Dr. Rauchwarter's team. The team at Cliff ... knows she will bring many benefits to the office as ... River Falls, WI. She finished dental assisting school and ... dental assisting in the Twin Cities, Milwaukee, California and Virginia. ...
(Date:9/16/2014)... Duke’s Chowder House Lake Union is ... and Gratafy for a fun evening of tech networking. ... cemented. With the growth of companies in these sectors, there’s also ... work in tech and at startups to connect with each other. ... to host events for their peers to meet and mingle in ...
Breaking Medicine News(10 mins):Health News:iFitDress.com: One Shoulder Evening Gown Collection Unveiled Online 2Health News:Best Windows Web Hosting Suppliers Recommended By SEO Hosting Review Site Top10BestSEOHosting.com 2Health News:Paradigm Physical Therapy Introduces Dry Needling 2Health News:Cliff Lake Dental Care Announces Newest Team Member 2Health News:Seattle Seafood Restaurant Duke’s Chowder House Partners with Rebls & Gratafy for Tech Networking Happy Hour Event. 2Health News:Seattle Seafood Restaurant Duke’s Chowder House Partners with Rebls & Gratafy for Tech Networking Happy Hour Event. 3
... ... to familiarize themselves with the draft of the new Diagnostic and Statistical Manual (DSM), ... mental disorders in children and adults. , ... Arlington, VA (PRWEB) February 12, 2010 -- The National Alliance ...
... , MISSION VIEJO, Calif. , Feb. 12 ... the parent company of the Ensign™ group of skilled nursing, ... today that it expects to issue its fourth quarter and ... Wednesday, February 17, 2010 . , (Logo:   http://www.newscom.com/cgi-bin/prnh/20071213/LATH168LOGO ...
... , PITTSBURGH , Feb. 12 ... launched its free antibiotics program in September of 2009, and ... more than $3 million in free prescriptions for ... more than 590,000 prescriptions for free antibiotics have been filled ...
... , BEAVER, Penn. , Feb. 12 ... UMPS CARE Charities, are proud to announce that the 5th Annual UMPS ... in need. , NNDS and SlateXP are proud to support the ongoing ... umpires. The funds raised at the Golf Classic ensure that umpires will ...
... Feb. 12 Making healthy choices can be a difficult ... Northwest and Intermountain Region continues to support its community by offering ... health care system and rewards for living healthier – all through ... the latter half of 2009, myRegence.com earned 17 key ...
... 12, 2010Hypnosis has potential therapeutic value in children with ... or unexplained sensations of difficulty breathing and for lessening ... hypnosis as an adjunct to conventional treatment and its ... physiological changes are explored in a provocative paper in ...
Cached Medicine News:Health News:NAMI Encourages DSM-5 Discussion 2Health News:The Ensign Group Schedules Year-End 2009 Earnings Call for Thursday, February 18, 2010 2Health News:Giant Eagle Pharmacy Free Antibiotics Program Surpasses $3 Million in Free Prescriptions 2Health News:National Network of Digital Schools, SlateXP and UMPS CARE Raise $75,000 for Children 2Health News:National Network of Digital Schools, SlateXP and UMPS CARE Raise $75,000 for Children 3Health News:Industry Recognizes the Regence Health Engine for Excellence in Creativity, Innovation and Information 2Health News:Industry Recognizes the Regence Health Engine for Excellence in Creativity, Innovation and Information 3Health News:Hypnosis can relieve symptoms in children with respiratory diseases 2
(Date:9/16/2014)... , Sept. 16, 2014 Research and Markets ... Vaccines Market 2014-2018" report to their offering. ... immunity of animals. Animal vaccines are generally prepared from weakened ... in their healthy state. Some of the animal vaccines are ... as protein subunits or toxic components. These ...
(Date:9/16/2014)... NEW YORK , Sept. 16, 2014 EHE ... exams with a nationwide physician network, today announced that ... has been named an EHE-certified preventive care center. Through ... Tarzana region now have greater access to ... "EHE is proud to add Dr. Abrams ...
(Date:9/16/2014)... BOSTON , September 16, 2014 ... been growing faster over recent years. The Pharma 2020 ... and generic drugs for both domestic and foreign markets. ... with the political situation and the following political and ...      (Logo: http://photos.prnewswire.com/prnh/20140916/706080) ...
Breaking Medicine Technology:Global Animal Vaccines Market 2014-2018: Key Vendors are Bayer, Elanco, Merck, Novartis, Sanofi and Zoetis 2Global Animal Vaccines Market 2014-2018: Key Vendors are Bayer, Elanco, Merck, Novartis, Sanofi and Zoetis 3EHE International Certifies David Abrams M.D. as Its Newest Partner 2Global Medicines for Russia 2
... 28 Americans, confidence in their ability to access and pay for healthcare ... Reuters. , , , ... significantly in the next three months," said Gary Pickens , chief research officer ... The Consumer Healthcare Sentiment ...
... SILVER SPRING, Md. , April 27 The U.S. Food and ... treat severe and persistent asthma in certain adults. , ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO ) , ... The Alair Bronchial Thermoplasty System is intended for patients ages 18 and older ...
Cached Medicine Technology:Americans Losing Confidence in Their Ability to Access and Pay for Healthcare, According to Thomson Reuters Index 2FDA Approves New Device for Adults with Severe and Persistent Asthma 2FDA Approves New Device for Adults with Severe and Persistent Asthma 3
... The QuickLink™ Delivery System ... device designed to assemble ... SourceLink Connectors into seed ... and with variable seed ...
... is the first one-step 20 minutes rapid test ... 2 produced by Enterohemorrhagic Escherichia coli in human ... enrichment of fecal specimens and detects all Toxigenic ... separate result for Toxin 1 and 2 is ...
Classic, stylish, and preppy, this collection features men's, women's and unisex styles....
The Claiborne brand provides the perfect look for the man who wants to be comfortable and relaxed, yet look appropriate for each occasion....
Medicine Products: