Navigation Links
Prediction of seasonal flu strains improves chances of universal vaccine
Date:3/12/2013

Researchers have determined a way to predict and protect against new strains of the flu virus, in the hope of improving immunity against the disease.

Influenza is a rapidly spreading acute respiratory disease. Worldwide, annual seasonal epidemics of the flu result in 3-5 million cases of severe illness, and up to 500 000 deaths. A newly emerged virus can spread across 74 countries in 2 months.

The study led by the University of Melbourne with Monash University and international colleagues has found how to predict and potentially stop the mutating cells of the influenza virus, which escape our bodies' white blood cells (T cell) immunity.

Senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology at the University of Melbourne said the finding may lead to a new universal influenza vaccine to better protect against both seasonal and pandemic outbreaks.

This research, published in PNAS today, will also help researchers understand T cell immunity against other viral infections such as HIV, Hepatitis C and tumours.

"The introduction of a new influenza strain into human circulation leads to a rapid global spread of the virus due to minimal antibody immunity," Assoc Prof Kedzierska said.

"White blood cells called T cells are highly efficient in fighting influenza virus infection. Thus, established T cell immunity towards particular viral regions can provide 'universal' immunity against distinct seasonal and pandemic influenza strains.

"However, influenza viruses can mutate their genes to escape efficient T cells. This constitutes a major problem for a design of a universal vaccine.

In the current paper, researchers have unraveled how influenza viruses evade T cell immunity by introducing specific mutations within the viral proteins.

Professor Peter Doherty, a lead author of the study from the University of Melbourne said predicting and designing vaccines to protect against such mutants can promote T cell immunity.

"The studies suggested that an influenza vaccine that targets T cells and recognizes distinct virus strains could provide universal immunity against any future influenza strain," he said.


'/>"/>
Contact: Rebecca Scott
rebeccas@unimelb.edu.au
61-383-440-181
University of Melbourne
Source:Eurekalert

Related medicine news :

1. Breast cancer risk prediction model for African American women underestimates risk
2. Astro Clairvoyant Norah Guide for Premium Astrology Publishes New Blog Series on 2013 Predictions
3. Travel Services MyTSOnline Celebrates the Holidays by Extending Lifetime Memberships and Poking Fun at the Mayan End of World Prediction
4. Prepare for 2013 - Clair-Astrologist Norah Jones Goes Social; Read Her 2013 Zodiac Predictions
5. Certified Astro-Clairvoyant Norah Guide with Premium Astrology Makes New Year Predictions for 2013
6. Weather prediction task: Learning achievement with and without stress
7. Strains of antibiotic-resistant Staph bacteria show seasonal preference; Children at higher risk in summer
8. A Delicious, And Healthy New Seasonal Hot Chocolate Beverage, Xocai's Sipping Xocolate, Has Been Released By Marketing Xocolate International Corporation (MXI Corp)
9. Study examines role of seasonal prescribing changes in antibiotic resistance
10. NYC Doc Announces 3 Surprising Ways to Beat Seasonal Allergies
11. Does Your Child Have Seasonal Allergies or a Cold?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... (PRWEB) , ... June 26, 2016 , ... PawPaws ... a new product that was developed to enhance the health of felines. The formula ... , The two main herbs in the PawPaws Cat Kidney Support Supplement ...
(Date:6/25/2016)... ... ... Austin residents seeking Mohs surgery services, can now turn to Dr. Jessica Scruggs ... for medical and surgical dermatology. , Dr. Dorsey brings specialization to include Mohs surgery, ... Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn Goldstein, MD, ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... 2016 , ... The Pulmonary Hypertension Association (PHA) learned during ... two significant new grants to support its work to advance research and patient ... recognizing patients, medical professionals and scientists for their work in fighting pulmonary hypertension ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...  Collagen Matrix, Inc., ("Collagen Matrix") the driving ... collagen and mineral based medical devices for tissue ... Messer has joined the company as Vice ... growing portfolio of oral surgery, neurosurgery, orthopaedic and ... the Collagen Matrix executive team as an accomplished ...
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
Breaking Medicine Technology: