Navigation Links
Prediction of seasonal flu strains improves chances of universal vaccine
Date:3/12/2013

Researchers have determined a way to predict and protect against new strains of the flu virus, in the hope of improving immunity against the disease.

Influenza is a rapidly spreading acute respiratory disease. Worldwide, annual seasonal epidemics of the flu result in 3-5 million cases of severe illness, and up to 500 000 deaths. A newly emerged virus can spread across 74 countries in 2 months.

The study led by the University of Melbourne with Monash University and international colleagues has found how to predict and potentially stop the mutating cells of the influenza virus, which escape our bodies' white blood cells (T cell) immunity.

Senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology at the University of Melbourne said the finding may lead to a new universal influenza vaccine to better protect against both seasonal and pandemic outbreaks.

This research, published in PNAS today, will also help researchers understand T cell immunity against other viral infections such as HIV, Hepatitis C and tumours.

"The introduction of a new influenza strain into human circulation leads to a rapid global spread of the virus due to minimal antibody immunity," Assoc Prof Kedzierska said.

"White blood cells called T cells are highly efficient in fighting influenza virus infection. Thus, established T cell immunity towards particular viral regions can provide 'universal' immunity against distinct seasonal and pandemic influenza strains.

"However, influenza viruses can mutate their genes to escape efficient T cells. This constitutes a major problem for a design of a universal vaccine.

In the current paper, researchers have unraveled how influenza viruses evade T cell immunity by introducing specific mutations within the viral proteins.

Professor Peter Doherty, a lead author of the study from the University of Melbourne said predicting and designing vaccines to protect against such mutants can promote T cell immunity.

"The studies suggested that an influenza vaccine that targets T cells and recognizes distinct virus strains could provide universal immunity against any future influenza strain," he said.


'/>"/>
Contact: Rebecca Scott
rebeccas@unimelb.edu.au
61-383-440-181
University of Melbourne
Source:Eurekalert

Related medicine news :

1. Breast cancer risk prediction model for African American women underestimates risk
2. Astro Clairvoyant Norah Guide for Premium Astrology Publishes New Blog Series on 2013 Predictions
3. Travel Services MyTSOnline Celebrates the Holidays by Extending Lifetime Memberships and Poking Fun at the Mayan End of World Prediction
4. Prepare for 2013 - Clair-Astrologist Norah Jones Goes Social; Read Her 2013 Zodiac Predictions
5. Certified Astro-Clairvoyant Norah Guide with Premium Astrology Makes New Year Predictions for 2013
6. Weather prediction task: Learning achievement with and without stress
7. Strains of antibiotic-resistant Staph bacteria show seasonal preference; Children at higher risk in summer
8. A Delicious, And Healthy New Seasonal Hot Chocolate Beverage, Xocai's Sipping Xocolate, Has Been Released By Marketing Xocolate International Corporation (MXI Corp)
9. Study examines role of seasonal prescribing changes in antibiotic resistance
10. NYC Doc Announces 3 Surprising Ways to Beat Seasonal Allergies
11. Does Your Child Have Seasonal Allergies or a Cold?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... (PRWEB) , ... March 24, 2017 , ... ... Center, Sedona, Arizona’s Premier Center for Shamanic Healing and Spiritual Awakening, proudly ... Delgado, June 9--24, 2017. This sacred and spiritual journey during the Summer ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... the Advanced ERISA Benefit Claims Litigation seminar in Chicago, Illinois. She will ... The majority of cases litigated under ERISA involve claims for long-term disability benefits. ...
(Date:3/24/2017)... ... March 24, 2017 , ... Empower Brokerage, located ... training and leads programs. , In February, 2017, Empower Brokerage introduced their new ... Partners is designed to teach how to maximize their sales efforts, as well ...
(Date:3/24/2017)... ... March 24, 2017 , ... “Vintage and Harvest A ... minister and college Bible teacher residing in North Carolina with his wife, Anna Marie. ... blessed them with six grandchildren. David is also the author of “Shadow and Substance.” ...
(Date:3/23/2017)... ... , ... A recent report from the National Council on Teacher Quality (NCTQ) ... suggests, based on a review of GPA and SAT/ACT requirements at 221 institutions in ... It argues that this higher bar should be set by states, by the Council ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... , March 24, 2017 Today Stock-Callers.com ... stocks, which are: Neovasc Inc. (NASDAQ: NVCN), Hologic Inc. (NASDAQ: ... (NASDAQ: SSH ). These companies are part of ... gains on Thursday, March 23 rd , 2017, with the ... shares of health care companies in the S&P 500 were ...
(Date:3/24/2017)... 23, 2017  HealthMine surveys with 9,250 insured consumers ... health plan members want help from their plans in ... in their health, 2) help closing gaps in care, ... health and 5) relevant, real-time guidance. Meeting these needs ... costs. A Reason to Stay ...
(Date:3/24/2017)... -- The Board of Directors of Nordic Nanovector ... including the complete 2016 Annual Accounts with notes. The report ... website in the section Investor Relations/Reports and presentations/Annual Reports. ... For further ... Financial Officer Cell: +47-91-51-95-76 Email: ir@nordicnanovector.com ...
Breaking Medicine Technology: