Navigation Links
Predicting the return of prostate cancer: New Johns Hopkins study betters the odds of success
Date:7/2/2009

Cancer experts at Johns Hopkins say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease metastasis.

The new prediction method comprises the length of time it takes for PSA (prostate-specific antigen) to double, Gleason score (a numeric indicator of prostate cancer aggressiveness as seen under the microscope), and the interval between surgical removal of the prostate and the first detectable PSA level. According to Johns Hopkins investigators, combining these three measurements more accurately estimates risk that the cancer has spread than do other methods and should help determine which patients may benefit from additional therapy when PSA levels rise after surgery to remove the prostate.

Findings from the study presented at the June 2009 annual meeting of the American Society of Clinical Oncology (ASCO) may also help resolve the debate on when and in what form secondary treatments should occur.

"There is much debate on whether to prescribe immediate treatment for a man whose PSA begins to rise after he has had prostate cancer surgery, or to delay it," says Emmanuel Antonarakis, M.D., Johns Hopkins Kimmel Cancer Center investigator. "Studies suggest that most men live the same length of time overall whether they receive therapy at the first sign of a rising PSA or wait until the cancer has spread to other sites."

After reviewing the records of 774 men whose PSA rose after surgery to remove the prostate, the researchers found that Gleason score and two measurements for PSA were the strongest risk factors for prostate cancer metastasis. Men with Gleason scores in the highest range, between eight and 10, were twice as likely to develop metastatic cancer. In men whose PSA became detectable within three years after surgery, cancer was more than three times more likely to spread to other organs. Finally, m
'/>"/>

Contact: Amy Mone
amone1@jhmi.edu
410-955-1287
Johns Hopkins Medical Institutions
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Predicting fatal fungal infections
2. Researchers determine predicting factors of positive lung cancer diagnoses in chest radiographs
3. Predicting higher risk for prostate cancer diagnosis
4. U study shows MRI-based method holds promise for predicting treatment outcomes in patients with AF
5. Systolic and diastolic blood pressures together more useful for predicting cardiovascular risk
6. Progress Made in Predicting Breast Cancer Risk
7. Researchers discover strategy for predicting the immunity of vaccines
8. Genetic Testing No Real Help in Predicting Type 2 Diabetes
9. Predicting the future for patients with severe traumatic brain injury
10. Novel imaging approach may assist in predicting success of treatment for atrial fibrillation
11. Prototype test for predicting clinical outcome for melanoma patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... By Tara Haelle ... (HealthDay News) -- More than 100 genes have been ... new studies report. And researchers say they are ... overall that may contribute to the disorder. Autism ... by communication and social difficulties and repetitive behaviors. An ...
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician ... practices; OB GYN in Melrose Park, IL and ... contains important information about each of the care services and ... forms in English and Spanish. The navigation of the ... the website provide Dr. Furlin’s patients with important information regarding ...
(Date:10/30/2014)... 2014 USARAD Holdings Inc ... and specialty telemedicine solutions provider, including SecondOpinions.com ... existing teleradiology services at Mission Bend ER, it ... telemedicine services, to the state-of-the-art, 24/7, freestanding ER ... of this innovative partnership, there will be many ...
(Date:10/30/2014)... York (PRWEB) October 30, 2014 The ... (NAMS) came to a close on Saturday, October ... since the Society’s inception in 1989. NAMS is North ... and quality of life of all women during midlife ... aging. With over 2,000 physicians and thought leaders from ...
(Date:10/30/2014)... 2014 (HealthDay News) -- When it comes to heart disease, ... to delay care when they have symptoms that spell trouble. ... the hospital with a more severe or advanced stage of ... author Catherine Kreatsoulas, a Fulbright Scholar and research fellow at ... release from the Heart and Stroke Foundation of Canada. ...
Breaking Medicine News(10 mins):Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 3Health News:Highlights from The North American Menopause Society 25th Annual Meeting 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 3Health News:Women Often Ignore Signs of Heart Trouble 2
... the West. But a UK expert has warned that they ... for food, usually vegetables or legumes , that have been ... paste or thick liquid. ,The term comes from ... exclusively on breast or formula milk for the first six ...
... for the conflict in Sudan's Darfur region, where droughts ... Ki-moon said in an editorial published Saturday. ... and political shorthand - an ethnic conflict pitting Arab ... The Washington Post. "Look to its roots, though, and ...
... ultrasound early in pregnancy, combined with maternal blood analysis, ... Down Syndrome . ,ng of pregnant women ... analysis, has reduced the number of children born in ... tell the annual conference of the European Society of ...
... stigma is attached to it, especially when it involves children. But ... parents have told them that it was the same with Jonty. ... one of the most famous epileptics in sporting history- Jonty Rhodes. ... prowess, South African cricketer Rhodes who suffered epilepsy as a kid, ...
... based in Oak Brook, Illinois, in cooperation with US officials, ... "Thomas and Friends" wooden train toys made in China ... ,The toys, wooden vehicles, buildings and other train-set ... 2007, pose a danger to young children, who are likely ...
... found that non-invasive screening in early pregnancy reduces ... Brndum-Nielsen, of the Kennedy Institute, Glostrup, Denmark, ... with ultrasound early in pregnancy, combined with maternal ... born in Denmark with Down Syndrome by 50 ...
Cached Medicine News:Health News:Pureed Products Unnecessary and Harmful for Babies UK Expert 2Health News:Climatic Change Cause of Dafur Conflict-UN 2Health News:Early Pregnancy Test Reduces Down Syndrome in Children 2Health News:World Epilepsy Week - 2007 2Health News:World Epilepsy Week - 2007 3Health News:World Epilepsy Week - 2007 4Health News:World Epilepsy Week - 2007 5Health News:World Epilepsy Week - 2007 6Health News:World Epilepsy Week - 2007 7Health News:Lead Scare Causes Thomas to Derail 2Health News:Non-invasive Screening in Early Pregnancy Halves Down's Syndrome Births 2
(Date:10/30/2014)... 2014 Boston Scientific Corporation (NYSE: ... Credit Suisse Annual Healthcare Conference on Tuesday, November 11, ... Dan Brennan , executive vice president and chief financial ... at approximately 8:00 a.m. PT followed by a question ... the presentation and question and answer session will be ...
(Date:10/30/2014)... , Oct. 30, 2014 CVS Health (NYSE: ... new clinical affiliations with three leading regional health systems to ... The collaborating health systems include Baptist Health System in ... which include Commonwealth Health in Pennsylvania , ... Arizona , and Tennova Healthcare in Tennessee ...
(Date:10/30/2014)... --  BioLife Solutions , Inc. (NASDAQ: BLFS ... clinical grade hypothermic storage and cryopreservation ... for cells and tissues, today announced today that ... released on Thursday, November 6, 2014, and that the ... at 1:30 p.m. PST that afternoon. Management will provide ...
Breaking Medicine Technology:Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 3CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 4BioLife Solutions to Report Financial Results for Third Quarter 2014 and Provide Business Update on November 6, 2014 2
... 2 adjustable belt buckle. You adjust once and ... off your shoulders. And now theres our Lady ... anatomy. ,For additional back support try one of ... on the vertebrae and help lift the apron ...
The Easy Wrap Apron is now available with an attached Thyroid Collar. The Thyroid Collar is held on with velcro so it adjusts to fully protect the neck. This Apron with Collar is available in 5mm lea...
The major innovation in posterior stabilized (PS) knee design. Improve patellofemoral kinematics. Reduce wear rate potential. Increase resistance to posterior tibial dislocation. Achieve at least 120...
StelKast's Proven™ Knee System is a long term high quality solution based on a clinically proven and successful design....
Medicine Products: