Navigation Links
Preclinical study finds drug helps against pancreatic cancer
Date:10/24/2013

October 23, 2013(BRONX, NY)An investigational drug that disrupts tumor blood vessels shows promise against a rare type of pancreatic cancer, scientists at Albert Einstein College of Medicine of Yeshiva University have found. Their results were presented October 20 during a poster session at an international cancer conference.

The drug Zybrestat selectively targets and collapses tumor blood vessels, depriving the tumor of oxygen and making its cells die. In experiments involving a mouse model of pancreatic neuroendocrine tumors, Einstein scientists found that infusing mice with Zybrestat three times per week for four weeks resulted in significant antitumor activity compared with control mice given a placebo.

The findings were presented in Boston at the American Association for Cancer Research-National Cancer Institute-European Organisation for Research and Treatment of Cancer International Conference on Molecular Targets and Cancer Therapeutics. Presenting for Einstein was ZiQiang Yuan, M.D., research assistant professor of surgery at Einstein. The senior author is Steven K. Libutti, M.D., professor of genetics at Einstein and professor and vice chair of surgery at Einstein and Montefiore Medical Center, the University Hospital and academic medical center for Einstein.

Pancreatic cancer is the fourth-leading cause of cancer death in the U.S. According to the National Cancer Institute, more than 45,000 Americans will be diagnosed with pancreatic cancer in 2013 and more than 38,000 will die of the disease. Exocrine pancreatic cancer, the more common and usually fatal type
'/>"/>

Contact: Deirdre Branley
sciencenews@einstein.yu.edu
718-430-3101
Albert Einstein College of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Preclinical data support ongoing clinical trials testing IDO inhibitors as a treatment for cancer
2. Genetically-engineered preclinical models predict pharmacodynamic response
3. Preclinical study identifies master proto-oncogene that regulates ovarian cancer metastasis
4. Preclinical tests shows agent stops slippery proteins from binding, causing Ewing sarcoma
5. Mayo Clinic: Preclinical tests may lead to new approach to treat CNS lymphoma
6. Study Suggests Vaccine May Help Kids With Brain Cancer
7. Study reveals how cancer drug causes diabetic-like state
8. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
9. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
10. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
11. No Added Cancer Risk From Hip Replacement Materials: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/4/2015)... ... ... hacker gains access to someone’s email account, it can lead to all sorts of trouble, ... FTC issued a scam alert about a social engineering scam which cons a target ... by the hacker. All they have to do is click for a password reset ...
(Date:7/3/2015)... (PRWEB) , ... July 03, 2015 , ... ... Dori Friend opened registration for a new SEO training system called "Page ... guide for organic traffic generation has received glowing reviews from several well-known marketers. ...
(Date:7/3/2015)... ... July 03, 2015 , ... B. E. Smith, the ... to lead a national president recruitment for Regional Care, Inc. in ... B. E. Smith has recently placed more than 1,000 healthcare executives into organizations. ...
(Date:7/3/2015)... MO (PRWEB) , ... July 03, 2015 , ... Talcum ... website to replace their existing Talcum Powder Cancer Lawsuit Center website. Just as the ... talcum powder lawsuit news , offering timely lawsuit updates and ovarian cancer warning information. ...
(Date:7/3/2015)... ... July 03, 2015 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... says will reveal biblical truth and expose popular lies regarding proper relationships according to ... Have Sex”, immediately goes into the core of the subject by explaining why certain ...
Breaking Medicine News(10 mins):Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 2Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 3Health News:New FTC Scam Alert Shows Latest Example of Social Engineering Dangers 4Health News:Page One Engine - Review Of Dori Friend's SEO Training Course Released 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 2Health News:Talcum Powder Lawsuit News: Cancer Attorneys Launch Updated Mobile Site 3Health News:Yisrayl Hawkins Explains What the Bible Really Says about Sex in New Publication This Week 2
... its new expansion of the Pharmacogenomics Research Network (PGRN), ... Children,s Research Hospital a prestigious grant to focus on ... million grant is titled "PAAR4KidsPharmacogenomics of Anticancer Agents Research ... for 10 years. But now, we will be the ...
... Clinical trials in a variety of areas within interventional ... will directly affect the way that people with cardiovascular ... presented exclusively at TCT, will lead to new treatments ... Among the topics being covered are stenting in the ...
... being fed a poor diet of biscuits, ice-cream and soft ... in the journal Nutrition & Dietetics found some ... sugar foods, despite health authorities recommending exclusive breastfeeding to six ... tracked 587 women from two Perth maternity hospitals through regular ...
... The United States must focus on conserving the use ... from rapidly rising rates of antibiotic-resistant infections, according to ... nation,s supply of antibiotics is being depleted by resistance, ... that they no longer respond to widely-used treatments. Most ...
... pilot study suggests the hallucinogen psilocybin may be feasible ... and anxiety, with promising effects on mood, according to ... the January 2011 print issue of Archives of ... "In recent years, there has been a growing awareness ...
... and about one-fifth of fathers in the United Kingdom appear ... and 12th year of age, with the highest rates in ... online today that will appear in the November print issue ... of the JAMA/Archives journals. "Depression in parents is associated ...
Cached Medicine News:Health News:St. Jude researcher receives grant to focus on cancer pharmacogenomics in children 2Health News:TCT 2010 late breaking trials to have impact on practice of interventional cardiology 2Health News:TCT 2010 late breaking trials to have impact on practice of interventional cardiology 3Health News:TCT 2010 late breaking trials to have impact on practice of interventional cardiology 4Health News:What are babies made of? Research shows for some it is sugar, salt and not all things nice 2Health News:Pharmaceutical conservation key to slowing rise of antibiotic-resistant infections 2Health News:Pharmaceutical conservation key to slowing rise of antibiotic-resistant infections 3Health News:Hallucinogen appears safe, may improve mood among patients with advanced-stage cancer and anxiety 2Health News:Parents at highest risk for depression in the first year after child's birth 2
(Date:7/2/2015)... , July 2, 2015  The Green Exchange, ... the world,s first HIPAA compliant mobile app that connects ... farm-to-table fresh medical marijuana, announced today that their service ... Unlike Eaze, Meadow and more than half a dozen ... last year, Loud Cannabis is unique in that it ...
(Date:7/2/2015)... 2015   Decision Resources Group finds ... less frequent dosing as the highest unmet need ... burden on both patients and providers associated with ... injections, which are the current standard of care. ... is in development for dosing every two to ...
(Date:7/2/2015)... June 25, 2015 ... announced the addition of the "2015 ... Global Challenges, Emerging Technologies, Competitive Landscape" ... New Frontiers in Clinical Chemistry and Immunodiagnostics: ... a new seven-country strategic analysis of major ...
Breaking Medicine Technology:New Cannabis Delivery App Gets Product to Patient in Under 7 Minutes 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 3New Frontiers in 2015 Global Clinical Chemistry and Immunodiagnostics Market: Challenges, Emerging Technologies, Competitive Landscape 2
... ... tumors, SEATTLE, ... for advanced, metastatic prostate cancer has been,androgen-deprivation therapy. That is, the ... via,surgical castration (orchiectomy) or medical castration with,testosterone-blocking drugs. While such therapy ...
... Cell Lung Cancer, WASHINGTON, June 2 Today, ... from the pivotal Phase,III First Line in Lung Cancer ... Society of Clinical Oncology (ASCO), showed a,significant increase in ... non-small cell lung cancer (NSCLC)., "This is very ...
Cached Medicine Technology:Research Explains How Advanced Prostate Cancer Becomes Resistant to Androgen-Deprivation Therapy 2Research Explains How Advanced Prostate Cancer Becomes Resistant to Androgen-Deprivation Therapy 3Research Explains How Advanced Prostate Cancer Becomes Resistant to Androgen-Deprivation Therapy 4Lung Cancer Alliance Hails Announcement of New Erbitux(R) Data 2
... Offers one-handed operation for stent ... reduce unintentional stent movement. Allows user ... vessel wall apposition. Maintains tactile feel ... ,MicroMarker technology aids in visualization at ...
Vial with 100 Urine Reagent Test Strips, tests for glucose, protein, pH, blood, ketone, bilirubin, nitrite, urobilinogen, specific gravity. FOR LABORATORY USE BY QUALIFIED TECHNICIANS....
... the latest from Quality Mapping Solutions, ... designed specifically for implementing and managing ... superior design, functionality, security, and versatility ... managing a quality program., ,Based upon ...
... Q-Pulse is the UK's market-leading ... over 250 pathology laboratories in the ... Q-Pulse. In addition, hundreds of pathology ... Kong, South Africa and the United ...
Medicine Products: