Navigation Links
Precision radiation therapy may improve survival rates of some lung cancer patients
Date:3/16/2010

DALLAS March 16, 2010 A radiation therapy that uses multiple radiation beams to target tumors precisely has been shown to eliminate the primary tumor and ultimately may improve survival rates for lung-cancer patients unable to undergo surgery, according to UT Southwestern Medical Center physicians who led a national clinical trial of the treatment.

In a study appearing in the March 17 issue of The Journal of the American Medical Association, primary lung cancer did not recur in nearly 98 percent of the 55 participants who received stereotactic body radiation therapy (SBRT). More than half of these patients 56 percent were alive three years after diagnosis, while less than 20 percent ultimately died of metastatic lung cancer.

Dr. Robert Timmerman, vice chairman of radiation oncology at UT Southwestern, is lead author of the study and the principal investigator of the Radiation Therapy Oncology Group (RTOG) 0236 trial the first North American multicenter study to test SBRT in this patient population.

SBRT is a noninvasive procedure that delivers radiation beams to a tumor in a concentrated, extremely precise manner. Each of these beams is relatively weak and causes very little damage when traveling through the patient's body. When all the beams converge at the tumor, however, their cumulative effect delivers an extremely potent high dose aimed at destroying the target cells with great precision.

In this study, the 55 patients diagnosed with early-stage non-small cell lung (NSCL) cancer were unable to have their tumors surgically removed because of unrelated medical conditions, which left many of the subjects quite frail. Instead of conventional radiation therapy, which is often offered to such patients and is administered in 20 to 30 outpatient treatments, the participants were treated with SBRT during three outpatient treatments.

"Despite the high potency of the treatment, fewer than 20 percent of these extremely frail patients experienced a serious health decline," said Dr. Timmerman, who is considered one of the top international experts on stereotactic radiotherapy. "We believe these findings justify SBRT as a standard of care treatment for lung cancer in patients with serious medical problems like emphysema, heart disease and strokes.

"Primary tumor control is an essential requirement for the cure for lung cancer," he said. "SBRT as delivered in this clinical trial provided more than double the rate of primary tumor control as conventional radiotherapy described in earlier reports."

Dr. Timmerman said the patient outcomes in this study were better than researchers had expected and are similar to the risks for healthier patients who undergo radical surgery the standard treatment for early-stage NSCL cancer for the past century.

"The findings support ongoing clinical research that is investigating the use of SBRT in healthier patients who currently undergo surgery for their early-stage NSCL," Dr. Timmerman said. "SBRT is fast, convenient and very effective."


'/>"/>

Contact: Connie Piloto
connie.piloto@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert

Related medicine news :

1. Medicare Supplement Plan N Information and Rates Now Available Through Precision Senior Marketing
2. Precision Therapeutics President and CEO Sean McDonald Recipient of 2009 Pacesetters Award
3. National Minority Quality Forum Creates Advanced, Precision Tracking Tool to Address Prevalence of Peripheral Arterial Disease
4. Gerber Life Medicare Supplement Now Available Through Precision Senior Marketing
5. New Precision Radiation Treatment System Fights Cancer
6. Utilizing GPS-like Measurement Precision To More Accurately Determine Overall Performance
7. Reell Precision Manufacturing Creates a New Category of Torque Control Hinges, Check Out the Reell Torque Insert
8. Media Advisory: Medco CEO David B. Snow Jr. To Address American Enterprise Institute: Health IT: Empowering Precision Medicine
9. New laser for neurosurgery allows greater precision and efficiency for removal of complex tumors
10. Precision Optics Corporation to Effect Reverse Split and Ticker Symbol Change
11. Siemens Next-Generation of C-Arms Demonstrate Precision Imaging and Ease of Use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Brent Kasmer, a legally blind and certified personal trainer ... through a fitness app. The fitness app plans to fix the two major problems leading ... a one size fits all type program , They don’t eliminate all the ...
(Date:6/25/2016)... ... 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can ... CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn ... X . Simply select a ProHand generator and drag it above media or text ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... Conventional wisdom ... of success. In terms of the latter, setting the bar too high can result ... more than just slow progress toward their goal. , Research from PsychTests.com ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association (PHA) ... will receive two significant new grants to support its work to advance research ... anniversary by recognizing patients, medical professionals and scientists for their work in fighting ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... People across ... in Genome magazine’s Code Talker Award, an essay contest in which patients and their ... award to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as ... Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) ... Daylight Time). As previously announced on May ... definitive merger agreement under which Jazz Pharmaceuticals has commenced ...
(Date:6/26/2016)... -- Story Highlights: , ... health care industry is causing providers to review operating ... offers a suite of solutions for health care providers ... optimization: labor resource analysis, revenue cycle optimization and physician ... and better economics ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
Breaking Medicine Technology: