Navigation Links
Precise brain mapping can improve response to deep brain stimulation in depression
Date:4/28/2014

Experimental studies have shown that deep brain stimulation (DBS) within the subcallosal cingulate (SCC) white matter of the brain is an effective treatment for many patients with treatment-resistant depression. Response rates are between 41 percent and 64 percent across published studies to date.

One of the proposed mechanisms of action is the modulation of a network of brain regions connected to the SCC. Identifying the critical connections within this network for successful antidepressant response is an important next step.

A new study using MRI analysis of the white matter connections examined the architecture of this network in patients who demonstrated significant response to SCC DBS. Researchers found that all responders showed a common pattern defined by three distinct white matter bundles passing through the SCC. Non-responders did not show this pattern.

The study is published online in the journal Biological Psychiatry, with the title "Defining Critical White Matter Pathways Mediating Successful Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression."

"This study shows that successful DBS therapy is not due solely to local changes at the site of stimulation but also in those regions in direct communication with the SCC," says Helen Mayberg, MD, senior author of the article, professor of psychiatry, neurology and radiology and the Dorothy C. Fuqua Chair in Psychiatric Imaging and Therapeutics at Emory University School of Medicine.

"Precisely delineating these white matter connections appears to be very important to a successful outcome with this procedure. From a practical point of view, these results may help us to choose the optimal contact for stimulation and eventually to better plan the surgical placement of the DBS electrodes."

Led by researchers at Emory University, Case Western Reserve University and Dartmouth University, the study included 16 patients
'/>"/>

Contact: Robin Reese
404-727-9371
Emory Health Sciences
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Precise and persistent cell sabotage
2. New technology makes breast cancer surgery more precise at UC Irvine
3. Monroe, CT Dental Implants Are Now Computer Guided from Dr. Richard Amato for Precise Results
4. Precise Care is First Practice in Orange County to Offer SPG Block
5. Atlantic Spine Center Chief Surgeon, Dr. Kaixuan Liu, MD, PhD, Discusses the Evolution of Back Pain Treatment through More Precise Methods of Diagnostics
6. Cone Beam Imaging Technology is Now Used by Dr. Robert Mokbel for Precise Placement of Dental Implants in Fountain Valley, CA
7. Estimating babys size gets more precise
8. Study Suggests Vaccine May Help Kids With Brain Cancer
9. Epilepsy Leads to More Brain Abnormalities Over Time
10. UCLA Brain Injury Research Center gets NCAA funding for research on sports concussions
11. Why is traumatic brain injury increasing among the elderly?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... FL (PRWEB) December 26, 2014 India ... health insurance in the USA, announced today a new ... assist members in choosing the right plan for their ... the complexity out of the selection process when choosing ... by age group with only a few clicks. Many ...
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... (PRWEB) December 26, 2014 ... BambooFlooringChina.com combines beauty, strength and durability. Today, the ... promotion, which is valid until Jan. 30, 2015. ... grain of traditional hardwood. BambooFlooringChina.com is a well-known ... help consumers worldwide to find a reliable bamboo ...
(Date:12/25/2014)... December 25, 2014 Product liability lawsuits ... hip recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward ... an Order issued in the U.S. District Court, Northern ... convene an open conference on January 7, 2015, at ... Courthouse in West Palm Beach, Florida. The Conference is ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying women’s ... discounted prom dresses, most of which are priced under ... company, the promotion is valid until Jan. 22, 2015; ... UK market. , The prom dresses in this new ... A-line strapless, empire strapless chiffon, one shoulder, floor-length, V-neck ...
Breaking Medicine News(10 mins):Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2
... Partners Joins Forces with 130-Year-Old Organization, ... advance its,human-animal bond initiative, the American Humane ... to offer direct services in animal-assisted,activities and ... becomes a program of American Humane, which ...
... Johnson seeks insights into chronic, illnesses, including heart failure and ... ... VENTURA, Calif., Oct. 8 VivoMetrics announced today,that noted researcher Bruce ... the VivoMetrics LifeShirt(R) System to,the South Pole to collect valuable data for ...
... NEW YORK, Oct. 8 The Physicians Coalition,for ... fat dissolving,fat melting, injection lipolysis or other injectable ... medical treatments. These should not,be mistaken as an ... "Injections to unwanted fat, using compounded pharmaceuticals, ...
... Oct. 8 Health Management Systems,Inc. (HMS) today ... Peer Review,Systems, Inc. d/b/a/ Permedion, an independent health ... Ohio. With this,acquisition, HMS augments its portfolio of ... state Medicaid agencies and,managed care organizations. Permedion ...
... Population of Singapore to Use Eclipsys Solutions to Help Coordinate ... ... Facilities -, BOCA RATON, Fla., Oct. 8 Eclipsys,Corporation(R), (Nasdaq: ... healthcare provider in Singapore, has selected,Eclipsys Sunrise Clinical Manager(TM) as its ...
... Maryland for a fourth straight year, ranking 18th of the fastest-growing ... ... 8 CBaySystems and Services, Inc.,has been named for a fourth straight ... the 50 fastest,growing technology, media, telecommunications, and life sciences companies,in Maryland, by ...
Cached Medicine News:Health News:American Humane Association Adds Direct Services in Animal-Assisted Activities and Therapy 2Health News:American Humane Association Adds Direct Services in Animal-Assisted Activities and Therapy 3Health News:VivoMetrics' LifeShirt Going to South Pole to Uncover Clues to High-Altitude Illness 2Health News:VivoMetrics' LifeShirt Going to South Pole to Uncover Clues to High-Altitude Illness 3Health News:Consumer Safety Alert on Fat Dissolving Injections 2Health News:Consumer Safety Alert on Fat Dissolving Injections 3Health News:HMS Acquires Permedion to Expand Clinical Review Capabilities 2Health News:SingHealth Selects Eclipsys Solutions to Help Improve Clinical Outcomes, First Sunrise Clinical Manager Client Outside of North America 2Health News:SingHealth Selects Eclipsys Solutions to Help Improve Clinical Outcomes, First Sunrise Clinical Manager Client Outside of North America 3Health News:CBaySystems Selected to Receive Deloitte's 2007 Maryland Technology Fast 50 Award 2Health News:CBaySystems Selected to Receive Deloitte's 2007 Maryland Technology Fast 50 Award 3
(Date:12/24/2014)... Dec. 23, 2014   Assurex Health, a ... to healthcare providers for behavioral health and chronic ... $30 million in equity financing from new and ... , President and Chief Executive Officer. ... development of Assurex Health,s GeneSight ® ...
(Date:12/24/2014)... In response to urgent requests from the Deputy Minister ... Leone , Direct Relief delivered two 10-bed medical tents ... of local health workers who contract Ebola while fighting the ... center was constructed for foreign health care workers who may ... local Sierra Leonean health workers. With ...
(Date:12/22/2014)... Mass. , Dec. 22, 2014 ... leading manufacturer of innovative dialysis products, announced today ... has cleared its System One™ to perform hemodialysis ... known as home nocturnal hemodialysis. NxStage,s® System One ... by the FDA for this indication. ...
Breaking Medicine Technology:Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 2Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 3Assurex Health Secures $30 Million Financing Round to Continue Growth in Neuropsychiatric Pharmacogenomics 4First Ebola Treatment Unit for Local Health Workers Arrives in Sierra Leone 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3
... Capital Partners, a leading private equity firm, today announced ... Executive Officer of Nycomed, as Healthcare Operating Executive.  Mr. ... Nycomed during Avista,s ownership of the company, which was ... 9.6 billion. Under Mr. Bjorklund,s leadership, Nycomed ...
... Biotechnology, Inc., a development stage biopharmaceutical company, today ... worldwide commercial rights to neratinib, a potent, irreversible ... the epidermal growth factor receptors, ErbB1 (EGFR), ErbB2 ... studied in the neoadjuvant, adjuvant and metastatic settings ...
Cached Medicine Technology:Avista Capital Partners Appoints Hakan Bjorklund as Healthcare Operating Executive 2Avista Capital Partners Appoints Hakan Bjorklund as Healthcare Operating Executive 3Puma Biotechnology Announces Licensing Agreement with Pfizer for the Development and Commercialization of Neratinib, an Investigational Pan-HER Inhibitor; Closes $55 Million Private Placement and Completes Merger 2Puma Biotechnology Announces Licensing Agreement with Pfizer for the Development and Commercialization of Neratinib, an Investigational Pan-HER Inhibitor; Closes $55 Million Private Placement and Completes Merger 3Puma Biotechnology Announces Licensing Agreement with Pfizer for the Development and Commercialization of Neratinib, an Investigational Pan-HER Inhibitor; Closes $55 Million Private Placement and Completes Merger 4Puma Biotechnology Announces Licensing Agreement with Pfizer for the Development and Commercialization of Neratinib, an Investigational Pan-HER Inhibitor; Closes $55 Million Private Placement and Completes Merger 5
... ultrasonic aspirator, portable unit ... aspirator for the fragmentation ... available only outside the ... a very compact design ...
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Deflected large type, opening width 7.0 mm and length 5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Deflected large type, opening width 7.0 mm and length 5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Deflected large type, opening width 8.0 mm and length 5 mm....
Medicine Products: