Navigation Links
Precious metal could lead to next generation of cancer treatments
Date:12/8/2008

A precious metal which has never before been used in a clinical setting is being developed as an anti-cancer agent by University of Warwick researchers.

The metal, osmium, is closely related to platinum, which is widely used to treat cancers in the form of the drug cisplatin. Most famously, the cyclist Lance Armstrong was treated with cisplatin for testicular cancer.

Now the researchers, based in the Department of Chemistry, at the University of Warwick, are working closely with Warwick Ventures, the university's technology transfer office, to seek partners to help develop the potential of osmium through more extensive biological tests. The team will be presenting their work on 9 December at the national university technology showcase event, Bioversity.

Professor Peter Sadler, of the Department of Chemistry, explained: "Although cisplatin has been proven to be a very successful treatment; it is not useful for all kinds of cancer. It is also quite a toxic therapy, which can produce side effects and, from a clinical point of view, cells can also become resistant to platinum."

Osmium, with its special chemical properties, offers a new potential solution to an unmet clinical need. It has shown huge promise in treating several different types of cancer cell, including ovarian and colon cancers which have been developed and tested in the laboratory. The metal also has another advantage in that it is a much cheaper alternative to platinum.

Professor Sadler, along with post-graduate researcher Sabine van Rijt, is working to develop new compounds using Osmium, which they hope will lead to the development of drugs which could be used in combination therapies alongside existing drugs such as cisplatin.

"The compounds we have been developing are very promising," says Sabine van Rijt. "We're building a picture of how different compounds might interact with DNA in cancer cells. By making changes to the coating, or ligand,
'/>"/>

Contact: Peter Dunn
p.j.dunn@warwick.ac.uk
44-024-765-23708
University of Warwick
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Precious Time - Scientists discover how long heart failure patients can expect to live
2. Mothers Day Gives Woman Reason to Celebrate Lifes Most Precious Gift
3. MIPSolutions, Inc. Reduces Expense and Development Time Associated With Precious Metal Extraction
4. Cornell efficiency experts seek to save precious minutes in deploying ambulances
5. Donate Blood - A Simple and Precious Lifegiving Gift
6. Biosensors to probe the metals menace
7. Drug-Coated Stents No Riskier in Long Run Than Bare Metal Ones
8. Heavy metal slips down UK air quality charts
9. Drug-Coated Stents Better Than Bare-Metal Ones in Complex Cases
10. New sensor system improves detection of lead, heavy metals
11. Novel organic metal hybrids that will revolutionize materials science and chemical engineering
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... (PRWEB) , ... July 02, 2015 , ... ... solutions and management consulting services to the federal government, has announced they are ... Indefinite-Quantity (IDIQ), Business Management Office Support Services (BMOSS) contract not to exceed $250 ...
(Date:7/2/2015)... , ... July 02, 2015 , ... Hand sanitizers have ... current summer flu season, according to fresh water advocate and radio host Sharon Kleyne, ... hands. Kleyne cautions that for maximum effectiveness, hand sanitizers must be applied correctly and ...
(Date:7/2/2015)... Mountain Home, AR (PRWEB) , ... July 02, 2015 , ... ... to military families through their annual “Dog Tag” campaign. On Tuesday, July 7, ... For The Warriors® for nearly $800,000. Hope For The Warriors® is a national nonprofit ...
(Date:7/2/2015)... , ... July 02, 2015 , ... ... and development solutions for drugs, biologics and consumer health products, today announced that ... , Dr. Irmgard Neuper is the new General Manager at Catalent’s Schorndorf facility, ...
(Date:7/2/2015)... ... 02, 2015 , ... A team of quality control (QC) experts at GE ... QC laboratory for enhanced workflow. Now, Dr. Dunne’s lab has set a lofty goal: ... Healthcare Diagnostic Imaging network. , Join the team members for a new, free ...
Breaking Medicine News(10 mins):Health News:Octo Consulting Group Awarded IDIQ Contract for SEC Business Management Support 2Health News:Summer flu season hand sanitizers are most effective when correctly applied reports fresh water advocate Sharon Kleyne 2Health News:Summer flu season hand sanitizers are most effective when correctly applied reports fresh water advocate Sharon Kleyne 3Health News:Casey’s General Stores to Present Donation from “Dog Tag” Campaign to Hope For The Warriors® 2Health News:Casey’s General Stores to Present Donation from “Dog Tag” Campaign to Hope For The Warriors® 3Health News:Catalent Makes Two Key European Appointments in Oral Dose Manufacturing 2Health News:GE Healthcare Webinar Spotlights GE’s Own, Internal QC Lab Enhancements with Six Sigma 2Health News:GE Healthcare Webinar Spotlights GE’s Own, Internal QC Lab Enhancements with Six Sigma 3
... -- Low doses of a drug used to prevent ... considerably reduces hot flashes in patients undergoing anti-hormonal treatment, ... the result of a study carried out by North ... in Rochester, Minn. ,In presenting results of ...
... can feel a bit relaxed now. Genosis Inc, a US ... Fertell. The test has his and hers components ... device to measure the concentration of motile sperm, and a ... of egg quality. ,The availability of the two-in-one ...
... D.C. At the 54th Annual Meeting of SNM, ... nuclear medicine professionals, German researchers stated that ... accurately identifies patients responding to chemotherapy for esophageal ... to apply PET results from early metabolic response ...
... Organizations (AAPPO) is launching a new initiative to help ... patients diagnosed with diabetes as well as encourage ... AAPPO today kicked off its new ACT on Diabetes ... better care, and empower their patients to Take charge ...
... HIVmirror LLC, a Philadelphia-based company offering HIV positive ... announcing the launch of their innovative HIV progression ... its user-friendly Web site (http: www.hivmirror.com), empowers modern ... genetic code and its role in their potential ...
... ability to get in and see the doctor will be ... physicians, according to a new survey released today by ... national campaign to stop next year's 10 percent cut, was ... bleak picture for the future of Medicare. ,"The ...
Cached Medicine News:Health News:Hot Flashes in Men Treated for Prostate Cancer Reduced by Non-hormonal Drug 2Health News:Hot Flashes in Men Treated for Prostate Cancer Reduced by Non-hormonal Drug 3Health News:Fertility Test at Home Possible With a New Kit 2Health News:Esophageal Cancer Patients' Positive Responses to Chemotherapy Accurately Identified by PET 2Health News:AAPPO Launches ACT on Diabetes Initiative to Promote Improved Diabetes Care 2Health News:HIVmirror, LLC Launching Breakthrough Genetic Product for HIV Positive Consumer 2Health News:New AMA Survey Finds Medicare Cuts Will Hurt Seniors 2Health News:New AMA Survey Finds Medicare Cuts Will Hurt Seniors 3
(Date:7/2/2015)...   EVO Aesthetic Center and Wellness Spa ... aesthetics in Lakeway, Texas and ... Astanza Duality laser. The medical spa is focused on ... and laser procedures. Their addition of the Astanza Duality ... to their tattoo regret. "The large number ...
(Date:7/2/2015)... , July 2, 2015 Pharma Major ... in ZAO "Biocom" in Russia subject ... the Russian pharmaceutical market which recorded RUB 765 billion in ... markets in the world in 2014 (IMS Health). For over ... expected to continue with this trend, projecting Russia ...
(Date:7/2/2015)... 2015 The report "Silage Inoculants ... (Lactobacillus, Pediococcus & Enterococcus), Enzymes (Fibre-digesting & Starch-digesting), Crop-type ... Silage Inoculants & Enzymes Market is expected to reach ... from 2015 to 2020. Browse 75 ... 194 P ages and an in-depth ...
Breaking Medicine Technology:EVO Offers Advanced Laser Tattoo Removal With Astanza Duality In Lakeway, TX 2Lupin Acquires Biocom in Russia 2Lupin Acquires Biocom in Russia 3Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 2Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 3Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 4
... The BD Macro-Vue RPR (Rapid ... and Tear-drop Tests are nontreponemal testing ... syphilis described in A Manual of ... in this manual are the most ...
Rapid Plasma Reagin (RPR) set is a non-treponemal flocculation test that is,used for the qualitative and semi-quantitative determination of reagin,antibodies in serum or plasma from persons with syph...
Enzyme Immunoassay for the quantitative ( qualitative 0020, on request) determination of IgG Class antibodies to Rubella virus....
Donor Screen & Confirmation Kit...
Medicine Products: