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Pre-emptive treatment helped curtail skin toxicity with panitumumab
Date:1/16/2009

dpoint was the incidence of specific grade 2 or higher skin toxicities during the six week skin treatment period. The incidence of these toxicities was reduced more than 50% in the group that received pre-emptive treatment.

Quality of life was also assessed, using the Dermatology Life Quality Index. Patients who received the pre-emptive, prophylactic skin treatment regimen reported an improved quality of life, even around week three, which was the median time to first grade 2 or higher skin toxicity in the reactive skin treatment group.

"This study supports the notion that, as with other side effects to cancer treatments, it is more advantageous to treat prophylactically, than to wait for the side effect to fully develop," Dr. Lacouture said. "Futhermore, it shows that treating early on does not affect the benefit received from the anticancer therapy."


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Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

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