Navigation Links
Pourquié Lab uncovers mechanism contributing to appropriate formation of the spine
Date:6/18/2008

The Stowers Institute's Pourqui Lab has shed light on the mechanism causing animals to develop the appropriate number of vertebrae.

Vertebrae are formed from their embryonic precursors, called somites. The number of somites is consistent within a species, but varies significantly across species. By comparing the developing embryos of zebrafish, chicken, mice, and corn snakes, the team established an understanding of how an organism regulates the number of somites formed.

The findings were published today in Nature's advance online publication.

"We set out to understand why snakes form hundreds of vertebrae, while mice form about 50, and humans form just 33," said Cline Gomez, Ph.D., formerly a Postdoctoral Research Associate at the Stowers Institute and lead author on the paper. "We found that the control of both body elongation and vertebrae precursor size accounts for the different numbers of vertebrae in each of these species the smaller the vertebrae precursors are along the body length, the more vertebrae are formed."

The presomitic mesoderm is the middle layer of the three cell layers that form an early embryo. It increases in size as the somites form and then gradually shrinks until it is exhausted, terminating the process when the appropriate number of somites have been formed.

"In examining these diverse species, we discovered that the same process ended somite formation in each," said Olivier Pourqui, Ph.D., Investigator and senior author on the publication. "What influenced the number of somites in each species was the rate of somite formation. In snake embryos, somites form much more quickly than in the other species. As a result, there are more somites, but they are smaller."

Understanding the mechanism of vertebral column development in animals offers insight into how the spine forms in humans. A better understanding of the process may aid in the prevention or treatment of disord
'/>"/>

Contact: Marie Jennings
mfj@stowers-institute.org
816-926-4015
Stowers Institute for Medical Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New Research Uncovers how to Build and Maintain an Effective Competitive Intelligence Group
2. New Survey Uncovers Dirty Little Secrets About Americas Oral Care Habits
3. First-of-Its-Kind National Survey Uncovers Obstacles to Comprehensive Healthcare for People With Schizophrenia
4. First-of-Its-Kind National Online Survey Uncovers Obstacles to Comprehensive Healthcare for People With Schizophrenia
5. Study uncovers cause of flu epidemics
6. New Research Uncovers How to Build and Maintain an Effective Competitive Intelligence Group
7. Porn Nation Uncovers the Sexualization of America
8. Vaseline(R) Cocoa Butter Campaign Uncovers Skins Ability to Speak Volumes
9. Researchers uncover novel mechanism that balances the sizes of functional areas in the brain
10. UCSD study reveals the regulatory mechanism of key enzyme
11. Ancient mechanism for coping with stresses also gives cancer a boost
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 22, 2014 Healthcare professionals who ... continuing education at home or on-the-go via laptops, ... 20 brand new, premium Seminar-on-Demand CE courses. The ... over 2,000 hours of CE course ... educational experience. With such a diverse library, there’s ...
(Date:10/22/2014)... Akeso Biomedical, Inc. , a privately held ... infections, microbial biofilms, and chronic wounds, announced that Dr. ... , Dr. Sinskey is a Professor ... of Technology, or MIT. He has been a member ... holds positions as Co-Director of the Malaysia-MIT Biotechnology Partnership ...
(Date:10/22/2014)... Maureen Salamon HealthDay Reporter ... part of conventional in vitro fertilization (IVF) -- the incubation ... place in a device inside the vagina, new research suggests. ... the device, called an INVOcell, might sharply cut costs for ... the technology more accessible to those who don,t live near ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 With a ... Gov. Charlie Crist made a brief fundraising stop at ... on Thursday. , Fresh from a debate last night ... take the stage for the first seven minutes because ... former governor described the incident in one word: "weird." ...
(Date:10/20/2014)... T.E.N., a technology and information ... that William H. Murray, renowned author and industry ... Leadership Award winner. Presented annually, the ISE® Luminary ... leader and industry practitioner for his or her ... information security industry. , Formerly with IBM, Murray ...
Breaking Medicine News(10 mins):Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:Akeso Biomedical Appoints Dr. Anthony J. Sinskey to Board of Directors 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4
... disease is now reported to have spread in about 26 ... the disease is not fatal it weakens the immune system ... reported in Tasmania. Maharashtra state health minister Vimal Mundada said ... could be sensitized by this new disease and take necessary ...
... past two months while seven new HIV positive cases were identified ... alone, seven new HIV positive cases were identified in the district ... Chief Medical Superintendent Rajni Kant Gupta said., ,With this, the ... 30 of the infected were between 20 and 35 years, he ...
... up the lives of thousands of cancer patients, with hope ... gut.// Initial examinations of the drug have left a clue ... ,This drug called Sutent, nicknamed as the ... the cells to proliferate rapidly, as is the case in ...
... offered reduced price in fertility treatment if they donate eggs ... given permission for a scheme for ‘egg sharing' so as ... the women who agree for this scheme and pass on ... the cost of IVF treatment by almost half. ...
... Fatty acids found in oily fish won’t only make you ... fatty acids found in fish oil will help keep the ... of exercise.// , ,Professor Peter Howe, from the University of ... on 68 overweight-to-obese adults at risk of coronary disease and ...
... drew many activists who held a demonstration in Burlington after ... stance in support of the practice.// , The rally ... group kicked off World Breastfeeding Week. ,Activists marched ... that say breastfeeding is not just a private bond between ...
Cached Medicine News:Health News:IVF Price To Be Reduced If Women Opt For Egg Sharing Scheme 2Health News:IVF Price To Be Reduced If Women Opt For Egg Sharing Scheme 3Health News:Fatty Acids In Fish Oil Helps Fight Obesity 2Health News:Wide Support for Breast feeding 2
(Date:10/22/2014)... 2014 Sanomedics International Holdings, Inc. (OTCQB: SIMH) ... Research & Data Services, demand for thermometers is expected ... 2018, as demand for more accurate digital thermometers continues.  ... world,s largest market for thermometers, and one of the ... International Holdings, Inc. Sanomedics International Holdings designs, ...
(Date:10/22/2014)... NORWALK, Conn. , Oct. 22, 2014  Recently ... (GERD) have bolstered the already substantial database of evidence. ... and adoption of Stretta therapy for sufferers ... of clinical evidence supporting Stretta therapy as ... coverage policies that make Stretta therapy available to nearly ...
(Date:10/20/2014)... , Oct. 20, 2014  Indianapolis interventional medical ... Toronto -based 3D visualization leader ... of Neurological Surgeons Annual Meeting that they have ... brain surgery. The collaboration is the first of ... to improve patient outcomes. NICO,s BrainPath® interventional access ...
Breaking Medicine Technology:Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2Recent Clinical Study Data Confirms Efficacy of Stretta Therapy - Spurs Additional Insurance Coverage and Financing Round 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5
... ... ... - Spasticity Affects a Significant Number of Post-Stroke ... , , ...
... Robbins & Myers, Inc. (NYSE: RBN ) announced today that its Board of Directors approved a regular cash dividend payment of $0.0425 per share. , ... , , ... ... The dividend is payable on May 7, 2010 to shareholders of record as of ...
Cached Medicine Technology:First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 2First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 3First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 4First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 5First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 6First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 7First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 8First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity 9
ROB-NEL Catheters (100% Latex-Free)...
100% Silicone Foley Catheter Kits 2-Way...
Coude Foley Catheters (Latex) 2-Way Amber...
Silicone Elastomer-Coated Latex Foley Catheters 2-Way (Pediatric)...
Medicine Products: