Navigation Links
Potential new approach to treat cognitive impairments in schizophrenia
Date:9/24/2007

Philadelphia, PA, September 24, 2007 -- A new study reports important evidence for a potential new treatment approach for those diagnosed with schizophrenia. Schizophrenia is considered one of the most devastating of the major psychiatric disorders, which has three distinct facets, often referred to as positive (hallucinations, delusions), negative (blunted emotions, reduced capacity for pleasure), and cognitive (impairments in attention, memory, and problem-solving) symptoms. The cognitive impairments associated with schizophrenia are the aspect of this disorder most strongly associated with the inability to function in the workplace.

The medications currently approved to treat schizophrenia block a subclass of dopamine receptors (dopamine D2 receptors). They have limited efficacy in treating the negative and cognitive symptoms of this disorder and they are frequently associated with significant side effects. Hence, there is an acute need to develop alternative treatments for schizophrenia that have fewer side effects and are more effective in treating cognitive and negative symptoms of the disorder, according to the authors of this study, scheduled for publication in Biological Psychiatry on October 1st.

Multidisciplinary work has led to the emergence of the glutamate system as a promising therapeutic target for [the] treatment of schizophrenia, says Bita Moghaddam, Ph.D., the corresponding author on the study. Abnormal function of brain circuits that utilize glutamate as a chemical messenger, particularly in brain regions including the prefrontal cortex and hippocampus, has been implicated in the cognitive deficits associated with schizophrenia. The glutamate-related circuit dysfunction associated with schizophrenia may be modeled, to a meaningful extent, by blocking the NMDA subtype of glutamate receptor. The authors now report that by administering 3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide or CDPPB, a drug that stimulates
'/>"/>

Contact: Jayne Dawkins
ja.dawkins@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Potential New Cancer Gene Identified
2. Lack of Smell And Its Potential Risks
3. New Blood Thinner Pill - First Potential Alternative to Warfarin in 50 years
4. The Potential Of Cadaver Transplantation Programme In India
5. Unwed mothers find it difficult to attract potential life partner
6. Another Potential Of Stem Cells Discovered: Used For Growing Cartilage
7. Unpasteurised juices found to be potential health hazards
8. The many facets of milk and its health potential
9. Artificial sweetener, Aspartame, may be the potential cause of lymphoma, leukaemia
10. Yoga Guru Ramdev Invited to Tap Ayurveda Potential by Jharkhand Govt
11. Alcohol a potential carcinogen: knocking on the door: pay heed!
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... The leather seat covers provided by ... to meet customers’specific product needs. Recently, the company has unveiled ... , The company wants to provide worldwide clients with ... seat cover industry for a long time. According to the ... at promotional rates. Among all the new products, Chevrolet ...
(Date:8/22/2014)... AcousticSheep LLC participated in one of the ... first Color Run – otherwise known as the “Happiest 5K on ... over 10,900 participants from Erie, surrounding areas, and even from as ... of the largest running events put on in Erie, PA yet ... 5K on the Planet.” The event took place on August 9, ...
(Date:8/22/2014)... August 22, 2014 For the fourth ... reward and recognition industry, has received a prestigious level ... growth rate of 134%, TharpeRobbins remains on the exclusive ... America. TharpeRobbins was previously on the list in 2010, ... be included in this distinguished list for a fourth ...
(Date:8/22/2014)... Minorities in Orange and Los Angeles counties are among ... and recovery from trauma. Casa de Familia is one local ... minorities and the help they need. A local fitness ... between mental and physical health. , Fountain Valley Fit Body ... camp, located at 16560 Harbor Blvd., Suite D in Fountain ...
(Date:8/22/2014)... Medical Solutions, the nation’s third-largest Travel Nurse ... the Inc. 5000 list, amongst a highly competitive field. ... on the list, with 300% growth over a 3-year ... seventh time in the last eight years that Medical ... including one year on the Inc. 500, indicating an ...
Breaking Medicine News(10 mins):Health News:Custom 1993-1996 Chevrolet Camaro Leather Seat Covers Now for Sale at Lseat.com 2Health News:RunPhones® Reveals Erie, PA Enthusiasm Impressed Color Run Director 2Health News:RunPhones® Reveals Erie, PA Enthusiasm Impressed Color Run Director 3Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 2Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 3Health News:Fountain Valley Fit Body Boot Camp Announces Fitness Boot Camp Fundraising Event for Casa de Familia 2Health News:Fountain Valley Fit Body Boot Camp Announces Fitness Boot Camp Fundraising Event for Casa de Familia 3Health News:Medical Solutions Earns Position on the 2014 Inc. 5000 List 2
... , , ... CVS ) announced today that it has named Andrew ... the company,s retail-based health clinic subsidiary, and as Senior Vice President/Associate ... Dr. Sussman will be responsible for all clinical services and daily ...
... , PASO ROBLES, Calif., July 28 ... California, will make silicone micro-implants such as surgical drains, catheter ... not routine is the incredibly precise tolerances demanded of these ... achieving consistently precise results to within .001 inch is no ...
... , , New ... organizations , , WASHINGTON, July ... ability to show employers and purchasers that their on-going business ... help health care management companies achieve accreditation, URAC ...
... , MAITLAND, Fla. , July 28 ... treatment for infants with plagiocephaly and other head shape abnormalities, opened ... The Center currently also has offices in the Baltimore and Dallas ... orthoses, also commonly referred to as a cranial helmets or headbands. ...
... , , HOUSTON, July 28 ... finds that Houston Northwest Medical Center has received a Five-Star Rating ... for Bariatric Surgery in 2009/2010. , , HealthGrades ... American Hospitals Study, which analyzes patient outcomes for the most ...
... HARBIN, China, July 28 /PRNewswire-Asia-FirstCall/ -- China ... Company") (Nasdaq: CSKI ), a,leading fully integrated ... China ("PRC"), today announced that the,Company is scheduled to ... in early August, 2009. , ...
Cached Medicine News:Health News:CVS Caremark Names Andrew J. Sussman, M.D., as President/Chief Operating Officer of MinuteClinic 2Health News:CVS Caremark Names Andrew J. Sussman, M.D., as President/Chief Operating Officer of MinuteClinic 3Health News:When You Make Things That Get Implanted in People, Small Things Count 2Health News:URAC Launches New eLearning Courses for Health Care Management Accreditation 2Health News:URAC Launches New eLearning Courses for Health Care Management Accreditation 3Health News:URAC Launches New eLearning Courses for Health Care Management Accreditation 4Health News:New STAR Cranial Center of Excellence Offers Cutting-Edge Treatment to Central Florida Infants 2Health News:New STAR Cranial Center of Excellence Offers Cutting-Edge Treatment to Central Florida Infants 3Health News:New STAR Cranial Center of Excellence Offers Cutting-Edge Treatment to Central Florida Infants 4Health News:New STAR Cranial Center of Excellence Offers Cutting-Edge Treatment to Central Florida Infants 5Health News:Houston Northwest Medical Center's Bariatric Program Rated Top 15% in the Nation by HealthGrades 2Health News:Houston Northwest Medical Center's Bariatric Program Rated Top 15% in the Nation by HealthGrades 3Health News:China Sky One Medical, Inc. to Conduct Non-Deal Roadshow in Hong Kong and Singapore 2
(Date:8/22/2014)... ITHACA, N.Y. , Aug. 22, 2014 /PRNewswire/ ... computed tomography (CT) imaging facility, is using the ... 4D and even 5D imaging to researchers and ... just launched, asks "What would YOU do if ... the possibility to researchers and explorers everywhere, from ...
(Date:8/22/2014)... 22, 2014 /PRNewswire/ - SQI Diagnostics Inc. (TSX-V: ... commercializes proprietary technologies and products for advanced microarray ... a Master Service Agreement to contract with a ... assays. During the initial phase of this agreement, ... working prototype of one of the customer,s assays, ...
(Date:8/21/2014)... AUSTIN, Texas , Aug. 21, 2014  Vermillion, ... company focused on gynecologic cancers and women,s health, has ... of Sales and Managed Markets. Ms. Bauzon ... traction and expanding payer coverage for laboratory services companies. ... most recently with PerkinElmer, Inc., where she held the ...
Breaking Medicine Technology:Cornell's X-ray Imaging Lab Director Uses Kickstarter Campaign to "Democratize" Advanced 3D Imaging 2SQI Diagnostics Contracted to Automate Pathogen Detection Assays 2SQI Diagnostics Contracted to Automate Pathogen Detection Assays 3Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: