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Potential Alzheimer's disease risk factor and risk reduction strategies become clearer
Date:7/14/2014

mpleted a questionnaire on the frequency and intensity of exercise during their lifetime. After following the participants for about three years, the researchers found that a history of moderate physical exercise in middle age was associated with a significantly decreased risk of MCI progressing to dementia. (The association did not hold for either light or vigorous exercise in middle age, or for any level of physical activity in late life.)

In a second study reported at AAIC, the researchers looked at the timing of physical exercise and the risk of new cases of MCI. The study participants were 1,830 older adults with normal cognition from the Mayo Clinic Study of Aging. Participants underwent neurological evaluations, cognitive tests, and a self-reported questionnaire about physical exercise habits in mid-life and late-life, and were followed for an average of 3.2 years. The scientists observed that light physical exercise in mid-life and late-life were associated with decreased risk of incident MCI. Additionally, vigorous mid-life as well as moderate late-life physical exercise were associated with decreased risk of incident MCI.

"In our studies, we found that physical exercise at various levels, especially in mid-life, is beneficial for cognitive function," Geda said. "These are intriguing results, but they are not yet conclusive. More research is needed to determine the extent and nature of physical activity in protecting against MCI and dementia."

Poor Sleep Is Associated with Higher Dementia Risk In Veterans; PTSD More Than Doubles That Risk

It is known that sleep disturbance is a risk factor for cognitive decline and dementia, but this association has not been carefully investigated in older veterans. At AAIC 2014, Kristine Yaffe, M.D. of the University of California, San Francisco and colleagues reported on the results of a retrospective study of sleep disturbance and dementia among 200,000 veterans age 55 and older
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Contact: Alzheimer's Association Media Line
media@alz.org
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Alzheimer's Association
Source:Eurekalert

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