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Potassium loss from blood pressure drugs may explain higher risk of adult diabetes
Date:11/24/2008

d a history of diabetes. In the original study, potassium levels were monitored as a safety precaution to guard against irregular heartbeat, a condition that can result from low potassium.

The results, published online this month in the journal Hypertension, showed that for each 0.5 milliequivalent-per-liter (MEq/L) decrease in serum potassium, there was a 45 percent increased risk of diabetes. None of the people in the group receiving the fake drug developed low potassium levels. Shafi says these findings should encourage physicians to establish a potassium baseline by checking hypertensive patients' medical records to determine their potassium levels before prescribing thiazides.

"We would normally look at the number only after six weeks of treatment to make sure it was not low enough to cause heart problems. As a result, we might not be aware that it dropped significantly from where it was before treatment putting the patient at risk for developing diabetes," says Shafi.


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Contact: Eric Vohr
evohr1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
Source:Eurekalert

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