Navigation Links
Possible new cancer treatment identified
Date:4/19/2012

New research findings show how it may be possible to render cancer tumours harmless without affecting the other cells and tissues in the body. The findings apply to cancers including breast, lung and bowel cancer. The study was carried out at Lund University in Sweden.

Many of the most common chemotherapy drugs used to treat cancer have serious side effects because they not only affect the cells in the cancer tumour, but also the cells in the rest of the body.

Researchers at Lund University have now found a connection between two proteins that in different ways control cell division and the possibilities for a cancer tumour to develop. The retinoblastoma protein obstructs cell division and is absent in most types of cancer tumour. The new findings show that its absence leads to an increase in another protein, gamma-tubulin, which, when present in high levels, encourages the development of cancer tumours. However, if gamma-tubulin is blocked, the tumour cells die while the healthy cells survive.

The researchers are now looking for substances that can stop the effect of gamma-tubulin on cell division. This could form the basis for a new drug that works on various types of cancer and has a low risk of side effects if the substance is directed to the right place. This is because it is only the tumour cells that die.

"I judge the chances of finding a basis for a drug to be good, partly because there are already substances that block 'cousins' of gamma-tubulin", says Maria Alvarado-Kristensson, a researcher at Lund University, who believes that, if all goes well, a drug could be ready for initial tests on patients, known as 'phase 1 testing', in 5-6 years' time.

In the study, tissue and genetic material from patients with various different types of cancer were studied: breast cancer, bladder cancer, small-cell lung cancer, colon cancer and eye cancer. The two proteins were seen to play an important role in all these d
'/>"/>

Contact: Maria Alvarado Kristensson
Maria.Alvarado-Kristensson@med.lu.se
46-403-38391
Lund University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Researchers find possible genetic keys to surviving epithelial ovarian cancer
2. Researchers discover possible approach to the treatment of aggressive breast cancer
3. New hybrid NOSH aspirin as possible anti-cancer drug
4. Possible new pathway can overcome glioblastoma resistance
5. Women advised to avoid ZEN bust-enhancing supplements because of possible cancer risk
6. Cleveland researchers find possible breakthrough to relieve pain following spinal cord injury
7. Dana-Farber/Childrens Hospital Boston study identifies possible therapy for radiation sickness
8. Carotid artery stenting possible for high risk patients with lesions
9. Possible Genetic Link to Autism Identified
10. Its Possible to Come Down With Two Flu Viruses at Once
11. Precise early diagnosis of psychotic disorders possible
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... (PRWEB) November 27, 2014 Blood-borne pathogens ... many medical precautions and procedures in place to counter ... and disposal of things tainted with menstrual blood are ... design a simpler, more sanitary way to handle tampons ... an inventor from Sonora, Calif. , He then created ...
(Date:11/27/2014)... Dotinga HealthDay Reporter , WEDNESDAY, ... pre-wired to acquire a second language, new research suggests. But ... likely gain a brain boost, the small study finds. ... said study co-author Ping Li, co-director of the Center for ... even more interesting, Li said, that "the brain networks of ...
(Date:11/27/2014)... PITTSBURGH, PA (PRWEB) November 27, 2014 In ... an inventor from Sharpes, Fla., designed an easy way to ... lowering it/them. , He then created a prototype of the ... lift or lower a toilet seat and/or lid in a ... which prevents the spread of germs. Overall, it promotes good ...
(Date:11/27/2014)... November 27, 2014 Tylenol lawsuits ( ... allegedly injured by the medication are continuing to move ... is looking ahead to a status conference in December, ... Scheduling Order issued earlier this year, a conference in ... at 10:00 a.m. Items likely to be discussed at ...
(Date:11/27/2014)... DC (PRWEB) November 27, 2014 “LAB.C” was ... which features the latest and coolest technology products available to ... conducted the product review and shared with viewers ... for iOS and Android devices. , Consumers love portability and ... Their Cable Case for the iPhone5 and 5S has ...
Breaking Medicine News(10 mins):Health News:Some People May Be Pre-Wired to Be Bilingual 2Health News:Some People May Be Pre-Wired to Be Bilingual 3Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3Health News:Top Mobile Friendly Accessories were Featured on NewsWatch Television on October 30, 2014 2
... be more effective than a "fat" tax for deterring overweight ... study has found. A survey of 364 shoppers in random ... people from reaching for junk food, shoppersincluding those with the ... high fat content and included a note that the item ...
... D.C. It is important that the United States begin to ... APS believes that as a nation we need to be smart ... a clear understanding of what it means for America,s future jeopardizes ... For more than half a century, science and technology have been ...
... (HealthDay News) -- A lack of leptin contributes to the ... of body fat, but treatment with a synthetic form of ... a new study indicates. Extremely low levels of body ... as runners and dancers, and in those with eating disorders. ...
... April 8, 2011 Increased levels of a protein ... a major cardiovascular event in high-risk patients, according to a ... Measuring the amount of the protein, known as plasma renin ... tool to assess a patient,s risk and help prevent a ...
... HealthDay Reporter , THURSDAY, April 7 (HealthDay ... stroke appears to promote arm strength and function, Canadian ... approaches -- including the use of virtual reality [gaming] ... social participation," said lead researcher Dr. Gustavo Saposnik, director ...
... 2011A growing body of research suggests that caffeine disrupts ... poor control of type 2 diabetes, a major public ... of Journal of Caffeine Research : The International ... from Mary Ann Liebert, Inc. publishers, examines the latest ...
Cached Medicine News:Health News:Warning labels better than a fat tax, University of Alberta study shows 2Health News:US House budget plans would jeopardize scientific research facilities 2Health News:Hormone Linked to Absence of Periods in Women With Low Body Fat 2Health News: Video Games Might Aid in Stroke Rehab 2Health News: Video Games Might Aid in Stroke Rehab 3Health News:Caffeine and diabetes -- helpful or harmful? 2
(Date:11/26/2014)... PORTLAND, Oregon , November 26, 2014 ... or fascia of the organ protrudes through the wall of ... weak muscle area at birth are some of the causes ... inguinal, umbilical, hiatal, femoral, and incisional. An inguinal hernia is ... area. An umbilical hernia is found in the area of ...
(Date:11/26/2014)... YORK , Nov. 26, 2014 ... growing at a rate of 4%, with world ... to Kalorama Information. MRI and other types of ... diagnosis and treatment of numerous medical conditions in ... technologies and techniques. Kalorama,s report, Medical Imaging ...
(Date:11/26/2014)... SAN FRANCISCO , Nov. 25, 2014  goBalto, ... solutions, has been recognized as a winner of Red ... received a Global Top 100 North America award in ... the international technology landscape. Red Herring,s Top ... for identifying promising new companies and entrepreneurs. Red Herring ...
Breaking Medicine Technology:Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 2Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 3Global Hernia Repair Devices Market Size, Share, Trends and Forecast 2014 to 2018 - Big Market Research 4Kalorama: Steady Growth in the Medical MRI Market 2Kalorama: Steady Growth in the Medical MRI Market 3goBalto Selected as a 2014 Red Herring Top 100 Global Company 2goBalto Selected as a 2014 Red Herring Top 100 Global Company 3
... Where: Laemmle,s Town Center 5, 17200 Ventura Blvd., Encino ... p.m. VIP and remarks following at 4 p.m. Pioneering ... What: Premiere screening of "CODY," the inspiring story of ... Narrated by Glenn Close, the film tells the story of ...
... April 16 Trubion Pharmaceuticals, Inc. (Nasdaq: ... present data regarding its SCORPION(TM) multispecific therapeutic technology ... Association of Cancer Research (AACR) in Denver, April ... present data demonstrating the selectivity and high potency ...
Cached Medicine Technology:University of Redlands Student Cody Unser Documentary Run to Start Today in L.A. 2Trubion Pharmaceuticals, Inc. Announces Upcoming Presentation at the 2009 American Association of Cancer Research Annual Meeting 2Trubion Pharmaceuticals, Inc. Announces Upcoming Presentation at the 2009 American Association of Cancer Research Annual Meeting 3
SHIONORIA BNP,is a reagent used in the measurement of blood BNP. The blood BNP test allows accurate estimation of coronary functions....
... assay method for the semi-quantitative determination ... in human serum. The results of ... as an aid in the diagnosis ... associated with elevated anti-neutrophil cytoplasmic antibodies ...
... determination of Ang II is ... the pharmacological effect and efficiency ... angiotensin converting enzyme inhibitors (ACE ... antagonists as well as for ...
... The SAS RSV antigen ... rapid assay for the presumptive ... antigen directly from nasopharyngeal specimens ... This one-step 15 minute test ...
Medicine Products: