Navigation Links
Possible Gene Regions for Schizophrenia Located
Date:7/1/2009

Immune function genes also in the same area, researchers say

WEDNESDAY, July 1 (HealthDay News) -- Immune function may play a role in schizophrenia, say scientists who found that schizophrenia patients have genetic variations on a section of chromosome 6 that contains numerous genes associated with immune response.

That region of the human genome has not previously been suspected as a risk factor for schizophrenia, which affects about 1 in 100 people. It was already known that genetics account for about 80 percent of risk for schizophrenia. Most cases of the mental health disorder are believed to be caused by interactions between a large number of genes.

"That makes it hard to tease out, in a statistically significant way, any of these schizophrenia-associated genes," Dr. Douglas Levinson, director of the Program on the Genetics of Brain Function at Stanford University School of Medicine, said in a news release from the university.

But studying a large number of people can reveal that information, so Levinson and colleagues analyzed DNA data from three studies that included 27,000 people -- 8,000 with schizophrenia and 19,000 people without the disease.

The study participants were restricted to those of European ancestry. This was done in order to exclude numerous non-disease-related genetic differences that would have to be sorted through if participants had different ancestries.

The researchers used the latest genetic technologies to search for tiny genetic variations called single base-pair polymorphisms (SNPs). They found that the largest genetic differences between people with schizophrenia and those without the disease were found on chromosome 6.

The findings are presented in three papers published online July 1 in the journal Nature. "The papers present the first highly significant findings of gene regions associated with schizophrenia risk," Levinson said.

He added that "these findings show that our genetic methods are working and that the genetic underpinnings of schizophrenia can be understood. Similar methods have produced critical new discoveries in many other common diseases, once very large numbers of people could be studied. Now we see that the same approach works for psychiatric disorders like schizophrenia."

More information

Mental Health America has more about schizophrenia.



-- Robert Preidt



SOURCE: Stanford University School of Medicine, news release, July 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Possible benefit from online genetic testing for lung cancer
2. WinCo Foods Voluntarily Recalls Beef and Ground Beef Sold at Some Stores Between May 9 and May 15, 2009 Due to Possible Contamination
3. Statement from IDF on studies suggesting possible link between insulin glargine and cancer
4. Omega-3 Fatty Acids Key to Fetal Development - Possible Mercury Contamination Concerns in Some Fish Oil Avoided With Plant-based DHA in PreNexa(R) Prenatal Vitamins
5. Study Finds Possible Genetic Indicator of Colorectal Cancer
6. Medical Malpractice Survivors Decry Possible Stripping of Rights in Presidents Health Care Plan
7. New skin cancer patch: Possible alternative to surgery
8. Scientific Study Makes it Possible to Measure Connection Between People
9. Dangerous college drinking: Prevention is possible, studies suggest
10. Asthma Drugs Get Precaution Labeling for Possible Psychiatric Side Effects
11. UNC scientists identify growth factor as possible cancer drug target
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Possible Gene Regions for Schizophrenia Located
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned by ... to enhance the health of felines. The formula is all-natural and is made from ... the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... California (PRWEB) , ... June 25, 2016 , ... "With ... fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... customizable and all within Final Cut Pro X . Simply select a ProHand ...
(Date:6/25/2016)... ... 25, 2016 , ... Dr. Calvin Johnson has dedicated his ... implemented orthobiologic procedures as a method for treating his patients. The procedure is ... to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use to help ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
(Date:6/23/2016)... 23, 2016  The National Pharmaceutical Council (NPC) ... health policy research organization as its newest member.  ... senior vice president and chief scientific officer, Mallinckrodt ... the NPC Board of Directors. ... has joined us in support of our efforts ...
Breaking Medicine Technology: