Navigation Links
Positive results from phase 1 clinical trials of cuprindro
Date:2/15/2008

Medical Therapies Limited today announced that it has completed its first in human clinical trial of Cuprindo™ with interim results from patient diaries indicating that Cuprindo™ is safe and well tolerated.

The trial subjects, healthy volunteers, reported 100% compliance with the dosing protocol which involved application of Cuprindo™ suppositories twice daily over a seven day period. In addition, post-trial colonoscopy on the subjects uncovered healthy mucosa and no evidence of rectal inflammation or ulceration.

The safety trial was conducted in preparation for a planned efficacy study in proctitis patients.

The trial has been a success confirming our pre-clinical safety information on Cuprindo™ and it paves the way for our efficacy study in patients with proctitis, said Medical Therapies Chief Executive Officer Maria Halasz.

While the trial was not geared to assess Cuprindo™s systemic efficacy, one subject reported relief in chronic joint pain after Day 4 of the trial. Results of the full biochemical analysis of the trial assays including information on systemic absorption characteristics of Cuprindo™ are expected in the coming weeks.

Proctitis is a debilitating disease characterised by inflammation and ulceration of the colon, resulting in tiny open sores that can bleed and produce mucus. Symptoms of the disease include chronic diarrhoea, bloody stools and, in severe cases, faecal incontinence.

Current treatments such as corticosteroids and immuno-modulators can cause serious side effects and provide no relief for up to 30% of proctitis patients. A topically applied safe treatment, such as a Cuprindo™ suppository, could provide a much needed alternative for the 1 in 60 people suffering from the disease.


'/>"/>

Contact: Dr. Stephanie Williams
williams@medicaltherapies.com.au
61-292-990-311
Research Australia
Source:Eurekalert

Page: 1

Related medicine news :

1. Single reader with CAD more efficient, yields fewer false positives, and possibly more sensitive
2. HPV-positive head and neck cancer patients fare better than HPV-negative patients
3. HPV-Positive Head and Neck Cancers Fare Better
4. Labopharm Reports Positive Results for Phase III Study on Once-daily Trazodone
5. Seeing our spouses more negatively might be a positive
6. Abbotts Kaletra(R) and Aluvia(R) (lopinavir/ritonavir) New Lower-Strength Tablet for Pediatric Use Receives Positive Opinion from EMEA
7. Eating out can have both positive and negative impact on obesity
8. Medco CEO Reiterates Guidance, Positive Outlook for 2008
9. Brain Turns to Positive Thoughts When Faced With Death
10. Anthracyclines improve survival in HER2-positive breast cancer patients
11. Six Positive Predictions for 2008, from SuperLife World Service
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... Atlanta, GA (PRWEB) , ... February 12, 2016 ... ... and relationship-marketing firm announced that nominations have closed for the ISE Southeast Awards ... categories will be announced at the ISE® Southeast Executive Forum and Awards Gala ...
(Date:2/12/2016)... ... February 12, 2016 , ... Every winter, someone is killed, injured or ... West Penn Burn Center, part of the Allegheny Health Network, has partnered with ... the “Space Heaters Need Space” campaign. , “Space Heaters Need Space” aims ...
(Date:2/12/2016)... ... February 12, 2016 , ... The Jones Agency, a family owned insurance ... is launching a cooperative charity drive with the Tarrant Area Food Bank in the ... individuals and families in need, the Tarrant County Food Bank offers hope and security ...
(Date:2/12/2016)... ... February 12, 2016 , ... Young Asset Protection, ... the beginning of the latest charity campaign in their community enrichment program. Art ... to this worthy cause are currently being accepted at: http://artexpressioninc.org/ . , ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... For Coast ... hygienist Suzan Sweeney, RDH, and dental assistant Terrell Moore shortly before 7 a.m. to ... dozens of dental professionals, donating their time and skills to help hundreds of uninsured ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)...  SI-BONE, Inc., a medical device company that pioneered the use ... surgical (MIS) device indicated for fusion for certain disorders of the ... Medicare Administrative Contractor (MAC) covering the states of Connecticut ... , Massachusetts , Minnesota , ... , Rhode Island , Vermont ...
(Date:2/12/2016)... -- On Thursday, Feb. 11, 2016, surgeons at the ... Austin Medical Center successfully completed the first robotic surgery ... Surgical System with Trumpf Medical,s advanced operating table, the ... M.D., colorectal surgeon at the Texas Institute for Robotic ... technology, which seamlessly combines the da Vinci Xi Surgical ...
(Date:2/12/2016)... BUFORD, Ga. , Feb. 12 2016  OMS ... office-based dental and medical practitioners, announced today the recent ... website offers visitors a variety of features that enhance ... purchase oral surgery supplies. --> ... Supply is a fairly new company that started in ...
Breaking Medicine Technology: