Navigation Links
Positive results for unprotected left main coronary artery PCI with drug-eluting stents
Date:6/22/2011

Patients with normal left ventricular function who undergo elective unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) with drug-eluting stents (DES) had favorable outcomes according to new research. Results of the multicenter, retrospective study are reported in the June issue of Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions (SCAI).

For patients with ULMCA disease, coronary artery bypass grafting (CABG), known commonly as heart bypass surgery, is the standard of care based on medical evidence that shows a survival advantage with this intervention. Current guidelines for PCI state that ULMCA stenting may be an option for patients who are at high risk for adverse surgical outcomes, but have a low risk for procedural complications. In patients with severe aortic calcification, cerebrovascular disease, or limited life expectancy angioplasty may be elected over heart bypass surgery.

The present study, led by Michael Lee, MD, FSCAI, from the University of California, Los Angeles (UCLA) Medical Center evaluated the safety and efficacy of ULMCA PCI with DES in patients with normal left ventricular function. Researchers used data from a multicenter international registry, identifying 221 patients who underwent elective PCI for ULMCA disease between 2002 and 2009. Patients in the study had a mean age of 68 years and 75% were male; 25% had diabetes, 39% had a history of heart attack, and 40% had a prior PCI.

"Our analysis confirms that elective PCI with DES in patients with normal left ventricular function is a safe and effective treatment for ULMCA disease," said Dr. Lee. In the first 30 days following angioplasty no cardiac death, target lesion revascularization (TLR), stent thrombosis, or stroke were reported. While no cases of Q-wave myocardial infarction occurred, seven patients had periprocedural myocardial infarction.

The authors found that event-free survival estimates for cardiac death and TLR at five years was 96% and 89%, respectively. Further analysis established that patient age of 75 years or older and a history of myocardial infarction were independent predictors of cardiac death. "Research comparing the safety and efficacy of ULMCA PCI with DES versus CABG are needed and results from a large multicenter trial are forthcoming." Dr Lee concluded, "ULMCA PCI may be a viable option for low-risk patients with normal left ventricular function."


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. FDA Approves Test That Spots HER2-Positive Breast Cancers
2. Young Adults Sometimes See Debt as a Positive
3. College students respond better to positive anti-binge drinking messages
4. Cancer in HIV-positive patients
5. Hit multiple targets for maximum benefit in HER2-positive breast cancer, studies suggest
6. Higher volume reduces false positives in screening mammography
7. Healthy lifestyle, positive attitude can help improve patient outcomes
8. Repeat MRI screening for breast cancer results in fewer false positives
9. Are positive emotions good for your health in old age?
10. Warning about benevolent sexism and mens apparently positive attitudes towards women
11. HIV-positive head and neck cancer patients benefit from radiation therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the American Institutes ... Research Meeting June 26-28, 2016, at the Hynes Convention Center in Boston. , ... advance care planning, healthcare costs and patient and family engagement. , AIR researchers ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June 14 ... The article goes on to state that individuals are now more comfortable seeking to ... operations such as calf and cheek reduction. The Los Angeles area medical group, Beverly ...
(Date:6/24/2016)... ... 2016 , ... Marcy was in a crisis. Her son James, eight, was out of control. ... and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... rocks at my other children and say he was going to kill them. If ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... PARK RIDGE, Ill. and INDIANAPOLIS ... caliber of students receiving a Lilly Diabetes Tomorrow,s Leaders ... hands. The 2016 scholarship winners, announced today online at ... refused to let type 1 diabetes stand in the ... Lilly Diabetes has supported the Foundation,s scholarship program since ...
(Date:6/23/2016)... Pa. , June 23, 2016 The ... in an outpatient dialysis facility.  Treatments are usually 3 ... 6 hours per visit, including travel time, equipment preparation ... a patient, but especially grueling for patients who are ... of a skilled nursing and rehabilitation centers for some ...
Breaking Medicine Technology: