Navigation Links
Positive Results From Peregrine Pharmaceuticals' Bavituximab Phase l HCV Trial Presented at AASLD Meeting
Date:11/5/2007

- Bavituximab Appeared Generally Safe and Well Tolerated at All Doses

Tested -

- Signs of Anti-viral Activity Seen at All Dose Levels - - Exploratory Analysis of Cytokine Profile Following Treatment Supports

Proposed Immunomodulatory Mechanism of Action -

TUSTIN, Calif. and BOSTON, Nov. 5 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a biopharmaceutical company developing monoclonal antibodies for the treatment of cancer and hepatitis C virus (HCV) infection, today announced that results from its Phase lb study of bavituximab in chronic HCV patients were discussed on Sunday in an oral presentation at the 58th Annual Meeting of the American Association for the Study of Liver Disease (AASLD) -- The Liver Meeting(R). The study results were presented by Dr. Eric J. Lawitz, a principal investigator of the Phase lb study and director of Alamo Medical Research.

The multiple dose, open label study was designed to assess the safety and pharmacokinetic properties of ascending dose levels of bavituximab administered as monotherapy in patients with chronic HCV infection. Other study objectives included evaluation of anti-viral activity as measured by changes in serum HCV virus levels and an exploratory analysis of changes in serum cytokine levels as a measure of bavituximab's ability to stimulate certain components of the immune system.

Results indicate that bavituximab was generally safe and well tolerated, with no dose limiting toxicities or serious adverse events reported. Anti-viral activity (decline of greater than or equal to 0.5 log10 reduction in HCV RNA) was observed at all dose levels and was most consistent i
'/>"/>

SOURCE Peregrine Pharmaceuticals
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine news :

1. AKELA Pharma Inc. announces positive results for the extension part of its Phase IIb Fentanyl TAIFUN(R) trial
2. UCLA/RAND study shows that many children of HIV-positive parents are not in their custody
3. Blue Cross and Blue Shield of Florida Reports Eighteenth Consecutive Year of Positive Performance
4. Nutrition model stresses positive experience of eating
5. Ultrasound plus mammography finds more cancers, but increases false positives
6. Oncolytics Biotech Inc. reports positive interim results of UK phase Ia/Ib trials
7. PEAK Surgical Announces Positive Surgical Incision Wound Healing Results With the PEAK PlasmaBlade(TM)
8. Facet Solutions AFRS(TM) Implant Demonstrates Positive Clinical Results After One Year Follow Up
9. Evotec Reports Positive Top-Line Results in Phase II Study With EVT 201 in Elderly Insomniacs With Daytime Sleepiness
10. A low prevalence of H pylori in HIV-positive patients
11. Drug Company-Funded Asthma Drug Studies More Positive
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2008)...ead to new therapies for preterm labor , ... say they,ve found the switch that activates the u...a finding that may lead to therapies for preterm l...ds the protein IP on the surface of these uterine ...ing pregnancy. , But researchers from Dartmout...
(Date:11/21/2008)...a., Nov. 21 During a m...Edward G. Rendell today remembered Lieutenant Gove...an important partner in public service, and a tire... , "As the first woman elected lieutenant gove...vant," said Governor Rendell. "Her family and her ...
(Date:11/21/2008)... Banzel proved effective against Lennox-Gastaut sy...ws) -- A new drug called Banzel (rufinamide) has b...vere form of epilepsy called Lennox-Gastaut syndro...d Friday. , The approval was based on results o...ts ages 4 to 30. Compared to patients who took a p...
(Date:11/21/2008)...lders Intend To Vigorously Protect Investment And ...ov. 21 Dr. Stephen Joff...ndment to their Schedule 13D with the U.S. Securit... filed a 13D disclosing ownership of 11.4% of LCA-...LasikPlus fixed-site laser vision correction cente...
Breaking Medicine News(10 mins):Health News:Pennsylvania Governor Rendell Remembers, Celebrates the Life of Lt. Governor Catherine Baker Knoll During Capitol Tribute 2Health News:Pennsylvania Governor Rendell Remembers, Celebrates the Life of Lt. Governor Catherine Baker Knoll During Capitol Tribute 3Health News:FDA Approves New Drug for Severe Epilepsy 2Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 2Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 3Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 4Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 5Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 6Health News:Founders & Former Executive Management Team of LCA-Vision Seek Change to Rescue Company 7
...loped a micro capsule coated with silicon, which c...ection.This microchip works by absorbing nutrient...ucing cells.Some diabetics have to inject insulin ...r blood sugar levels. The device is being develope...
...e of disability in the United States, affects more...ances in treatment options and educational efforts...d and poorly treated in the US. In fact, a recent ...ns with serious mental illness fail to receive ade...
...hat children have the greatest increase in bone mi...Children who do not take enough exercise are in da...ys the study. Many fail to strengthen up their ske...efore puberty, which is critical to building healt...
...evel electromagnetic fields (EMF) at home could do...national study has found. //The three-year review ...n Non-Ionizing Radiation Protection (ICNIRP) by si...nstitutions around the world. Leukemia, which deve...
Other Medicine News:
(Date:11/19/2008)... a contract development and,manufacturing organiz...st,phase launch of its contract facility in Delaw...he process, facility and capacity problems commonl...ow-volume clinical and,early-stage commercial ste...n invest over $100 million and four years to devel...
(Date:11/18/2008)... make a donation or send a Christmas Seals e-card ...ire/ -- Millions will receive Christmas Seals in t...Association. These decorative holiday stamps are p... to 1907 when the Lung Association led efforts to ... alive today have no vivid memories of how widespr...
(Date:11/18/2008)...luenza survey underscores that mothers need to get...Gold Medalist Kristi Yamaguchi joins initiative ,...e 78 percent of mothers in the United States consi...ening disease that can strike anyone, only half sa...this season, according to a new survey from the Am...
(Date:11/13/2008)...s Prior to Surgery, ARLINGTON HEIGHTS, Ill., Nov....ition before surgery in massive weight loss patien...ease surgical complications, accelerate,wound heal... levels,according to a study in the December issu...ficial medical journal of the American Society of ...
Breaking Medicine Technology:Isogen Launches Major New Facility to Address Global Biopharma Demand 2American Lung Association Celebrates 101st Annual Christmas Seals Campaign 2Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated 2Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated 3Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated 4Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated 5Video: New Survey Finds Mothers See Influenza as a Serious Health Threat, but Often Don't Get Their Families Vaccinated 6Plastic Surgeons Warn of Malnutrition in Body Contouring Patients 2Millennium Pharmacy Systems Expands into West Virginia 28877 1Millennium Pharmacy Systems Expands into West Virginia 28877 2LifeMasters Receives Full Accreditation for Disease Management Programs 28872 1LifeMasters Receives Full Accreditation for Disease Management Programs 28872 2LifeMasters Receives Full Accreditation for Disease Management Programs 28872 3Brain recognizes verbal oh dear wave 5738 1Brain recognizes verbal oh dear wave 5738 2Americans United for Life Assesses State Ballot Initiative Outcomes Predicts Regrouping and Strong Comeback in Next Election Cycle for Life Issues 28864 1Americans United for Life Assesses State Ballot Initiative Outcomes Predicts Regrouping and Strong Comeback in Next Election Cycle for Life Issues 28864 2Americans United for Life Assesses State Ballot Initiative Outcomes Predicts Regrouping and Strong Comeback in Next Election Cycle for Life Issues 28864 3
...Onset and Total,Sleep Time, and key secondary endp... met at both doses - Evotec to host a,conference c...BURG, Germany | OXFORD, England, June 4, 2007-- Ev...today positive top-line,results from its first pha...hronic primary insomnia. EVT 201 is a partial,posi...
...ebo-controlled Trial,Ever Conducted in CTCL Presen...CHICAGO, June 04, 2007 /PRNewswire/ -- Preliminary...lled clinical trial ever,conducted in patients wit...AK was more than twice as effective as placebo in ...L. [Abstract number 8026],The primary endpoint of ...
Other Medicine Technology:Evotec AG (DE) - Evotec Reports Positive Proof-of-Concept Top-Line,Results with ... 2Evotec AG (DE) - Evotec Reports Positive Proof-of-Concept Top-Line,Results with ... 3Evotec AG (DE) - Evotec Reports Positive Proof-of-Concept Top-Line,Results with ... 4Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in,Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL) 2Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in,Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL) 3Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in,Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL) 4Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in,Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL) 5Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in,Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL) 6
Vannas Capsulotomy scissors angled forward
Gills-Vannas side angled capsulotomy flat handle scissors
Vannas angled capsulotomy flat handle scissors
No. 1. 30 mm conventional blades. Thin well-rounded tips.
Medicine Products: