Navigation Links
Portola Pharmaceuticals Enters Worldwide License Agreement for Development and Commercialization of Novel Antiplatelet Drug Elinogrel
Date:2/11/2009

-- Portola to Receive $75 Million Upfront Cash Payment, $500 Million in Potential Milestone Payments Plus Royalties on Future Sales --

SOUTH SAN FRANCISCO, Calif., Feb. 12 /PRNewswire/ -- Portola Pharmaceuticals, Inc., a privately-held biopharmaceutical company developing innovative drugs that provide significant advances in cardiovascular disease, inflammatory disease and cancer, today announced an exclusive worldwide license agreement with Novartis to develop and commercialize elinogrel, Portola's novel, proprietary intravenous (i.v.) and oral P2Y12 ADP receptor antagonist currently in Phase 2 clinical development. Elinogrel has shown potential to offer clinical improvements over current anti-clotting medications in helping patients avoid heart attacks and strokes.

Under terms of the agreement, Novartis will make an upfront cash payment to Portola of $75 million. Portola is eligible to receive additional cash payments totaling up to $500 million upon achievement of certain development, regulatory and commercialization milestones. Portola will also receive royalties on worldwide net sales of elinogrel. In addition, Portola has an option to co-promote elinogrel in the United States limited to hospitals and specialty markets.

Novartis will fund all future Phase 3 clinical trials of elinogrel and share costs of ongoing and planned Phase 2 trials. The agreement also provides Portola with an option to co-fund Phase 3 clinical trials and other development activities in return for additional royalties. The agreement is subject to review by the U.S. government under the Hart-Scott-Rodino Act and becomes effective after the expiration or earlier termination of the waiting period (or any extension thereof).

"Novartis is a global leader in cardiovascular drug development and marketing, which makes it an ideal partner to help us achieve elinogrel's therapeutic and market potential," said Charles Ho
'/>"/>

SOURCE Portola Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference
2. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
3. Provectus Pharmaceuticals, Inc. Begins Phase 2 Clinical Trial for Metastatic Melanoma
4. Idenix Pharmaceuticals to Present at Two Upcoming Investor Conferences
5. Vista Partners Updates Coverage on Tapestry Pharmaceuticals
6. Transcept Pharmaceuticals, Inc. to Present at UBS 2007 Global Life Sciences Conference
7. Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc.
8. Amylin Pharmaceuticals to Webcast Corporate Overview During 43rd Annual Meeting of the European Association for the Study of Diabetes
9. Major Pharma Clinical Case Studies From Amgen, AstraZeneca, GSK, Intermune, Cephalon Inc, Sunesis Pharmaceuticals and Dartmouth Medical School During Fall Clinical Focused Programs
10. Provectus Pharmaceuticals, Inc. releases summary results of phase 1 metastatic melanoma study
11. Class Settlement Could Result in Considerable Savings for Certain Consumers of Prescription Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... iFitDress.com, the well-known wedding dress manufacturer and retailer, ... evening gowns . All items in the fresh collection ... $100. , iFitDress.com is among the hardest working ... best to help clients worldwide to keep pace with ... and professional. According to its development manager, all its ...
(Date:8/20/2014)... August 20, 2014 Today, Zane ... the publication of a new eBook, Affordable Care ... small business owners feel uncertain about how the ... and their bottom line. , The new eBook ... helps businesses navigate their upcoming health insurance decisions. ...
(Date:8/20/2014)... Dennis Thompson HealthDay ... U.S. teen birth rates fell dramatically during the past two ... a new government report shows. An estimated 4 million ... decline, according to researchers from the U.S. Centers for Disease ... out at me from the report," said Bill Albert, chief ...
(Date:8/20/2014)... An imaging study of chronic users of codeine-containing ... regions of brain white matter and associates these ... , Researchers used diffusuion tensor imaging (DTI) (an ... investigate the white matter integrity of chronic CCS ... the brain, including the inferior fronto-occipital fasciculus, which ...
(Date:8/20/2014)... Aug. 20, 2014 (HealthDay News) -- Loss of brain ... explain why many seniors have trouble falling and staying ... sleep disruption can be especially severe and often results ... The investigators analyzed data from the Rush Memory ... enrolled at age 65 and are being followed until ...
Breaking Medicine News(10 mins):Health News:iFitDress.com Releases a New Range of Cheap Evening Gowns 2Health News:Teen Birth Rate Has Dropped Dramatically in Last Two Decades: CDC 2Health News:Teen Birth Rate Has Dropped Dramatically in Last Two Decades: CDC 3Health News:Seniors' Sleep Woes May Be Linked to Loss of Brain Cells 2
... physical activities can mean much athletic activity that is ... are becoming quite a common cause of hospitalization for ... the2nd Annual Sports Medicine for Coaches Fall Sports Safety ... at New York City’s Hospital for Special Surgery, had ...
... of Nutrition Elaine Rush states that consumption of energy ... as caffeine contributes to obesity. // ,The ... caffeine and guarana (which also contains caffeine) causes the ... lemonade. "These results could have huge implications when you ...
... diagnosed in men and the risk of developing this ... form of therapy for prostate cancer remains still a ... available to patients: traditional open surgery, laparoscopic (also known ... ,Prostate cancer patients biggest concerns following these treatment ...
... make head-and-neck cancer patients feel as if they ... that the treatment may later cause difficulty swallowing, ... through the stomach wall. This however sometimes can ... head-and-neck surgeon William R. Carroll, M.D., and colleagues ...
... most of the northern sections of Uttar Pradesh. The ... according to reports from health officials. , ,On Saturday ... actual toll "is bound to be much higher" as many ... far over 900 patients have been admitted to different government ...
... of Medicine had discovered a drug that can help in ... the brain. The research results were published in // current ... may go a long way in helping workers working in ... clock., ,The study’s results are reported on-line today in ...
Cached Medicine News:Health News:All Play Is No Good For Health 2Health News:Obesity Can Be Caused By Consumption Of Energy Drinks 2Health News:Benefits Of Robotic Prostate Surgery- But At What Cost? 2Health News:Treatment For Reversal Of Effects Of Sleep Deprivation In Brain 2
(Date:8/20/2014)... Reportlinker.com announces that a new market ... The Impact of Healthcare Reform (PPACA) On ... http://www.reportlinker.com/p01618927/The-Impact-of-Healthcare-Reform-PPACA-On-the-US-IVD-Industry.html The "Patient Protection and ... that affects virtually every aspect of health care, ... take effect now. IVD manufacturers who have different ...
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com ... is available in its catalogue: ... Key Trends and Opportunities to 2017 ... Synopsis The report provides in depth ... Canadian personal accident and health insurance segment, ...
(Date:8/20/2014)... Reportbuyer.com has added a new market research report: ... This report analyzes the worldwide markets ... Product Segments: Implantable/Internal Cardiac Defibrillators, and External Defibrillators. The ... Canada , Japan , ... , Middle East & ...
Breaking Medicine Technology:The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 2The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 3The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 4The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 5The Impact of Healthcare Reform (PPACA) On the U.S. IVD Industry 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 2Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 3Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 4Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 5Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 6Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 7Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 8Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 9Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 10Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 11Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 12Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 13Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 14Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 15Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 16Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 17Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 18Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 19Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 20Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 21Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 22Personal Accident and Health Insurance in Canada, Key Trends and Opportunities to 2017 23Global Cardiac Defibrillators Industry 2Global Cardiac Defibrillators Industry 3Global Cardiac Defibrillators Industry 4Global Cardiac Defibrillators Industry 5Global Cardiac Defibrillators Industry 6Global Cardiac Defibrillators Industry 7Global Cardiac Defibrillators Industry 8Global Cardiac Defibrillators Industry 9
Express Elyte Systems....
... 2400 has minimal requirements ... low as 2 L/test) ... L/hour) thus maximizing operating ... rack handler facilitates continuous ...
Iron (Total/Ferene). Storage temp: 15 - 30 C. Linearity: 0 - 500 ug/dl. Expected values: from males 60 - 160 ug/dl, from females 43 - 140 ug/dl. Available with Calibrator and Number of test are 120....
Iron UIBC (UIBC Buffer + Color + Std.). An Automated analyzer test kits....
Medicine Products: