Navigation Links
Porphyromonas gingivalis accelerates inflammatory atherosclerosis in a mouse model
Date:1/4/2011

Atherosclerosis is the leading cause of death in the developed world. While a number of risk factors for atherosclerosis have been defined, scientists continue to study other possible risk factors for this disease. Recent epidemiological and experimental studies link infectious agents with the development of inflammatory atherosclerosis. A hallmark of chronic infection with the oral pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response. P. gingivalis induces a local inflammatory response that results in oral bone destruction, which is manifested as periodontal disease, an inflammatory disease that affects approximately 100 million people in the US. In addition to chronic inflammation at the initial site of infection, mounting evidence has accumulated supporting a role for P. gingivalis-mediated periodontal disease as a risk factor for systemic diseases including, diabetes, pre-term birth, stroke, and atherosclerotic cardiovascular disease.

In new studies Dr. Caroline Genco together with Dr. James Hamilton at Boston University School of Medicine have begun to define the precise mechanisms contributing to the link between infection with P. gingivalis and atherosclerotic disease. In elegant studies recently published (Atherosclerosis-12-22-10 online publication date) these investigators report on in-vivo high-resolution magnetic resonance imaging (MRI) to document P. gingivalis mediated inflammation and atherosclerosis in a mouse model. MRI is a novel modality that allows for detailed studies of atherosclerosis progression in the same animal that can depict the narrowing of the arterial lumen and small vessel wall areas. Genco and collogues demonstrate that P. gingivalis infection accelerates inflammation and atherosclerosis in the innominate artery, an artery that has a high degree of lesion progression. Lesions in the innominate artery express features characteristic
'/>"/>

Contact: Gina DiGravio
gina.digravio@bmc.org
617-638-8480
Boston University Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. LIMU Accelerates Growth Era With Brand Transformation
2. Stress accelerates breast cancer progression in mice
3. $4.37 million NCI grant accelerates recent laboratory finding in Ewings sarcoma
4. Inflammatory Bowel Ups Risk for Blood Clots
5. NIH grant will create behavioral health registry for pediatric inflammatory bowel disease
6. Prozac and Celexa exhibit anti-inflammatory effects
7. Physician's Pain Relief Cream Includes Patented Anti-inflammatory in New Formula
8. Feedback loop explains inflammatory effect on intestinal lining
9. Study Details Machinery of Immune Protection Against Inflammatory Diseases Like Colitis
10. Two New Phytochemicals with Anti-Inflammatory Activity Found in Noni Fruit
11. New research reinforces anti-inflammatory properties of tart cherries
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... 27, 2015 Smile Brands Inc. ( ... business support services to dental groups in the United ... affiliated Castle Dental office in Hendersonville, TN. ... 37075, this new Castle Dental office provides families with ... latest in comprehensive, quality dental care. Hendersonville marks the ...
(Date:3/27/2015)... Hawkins, Pastor and Overseer at The House of Yahweh in ... is through the Laws of Peace written in the Holy ... article titled, “Yahweh’s Way-The Great Difference” focuses on the past ... the original biblical instructions has caused mass chaos worldwide. ... in the world is based on man-made laws that will ...
(Date:3/27/2015)... The Thomas Scattergood Behavioral ... foundation committed to raising its voice to improve ... , The Scattergood Foundation and The Kennedy Forum ... and Practice through the Annual Scattergood Foundation Innovation ... is designed to guide the IBS sufferer through ...
(Date:3/26/2015)... Alamitos, Calif. (PRWEB) March 26, 2015 ... the grocery store. Fresh produce are today’s traffic magnets. ... a particular supermarket because of their produce department, according ... important than ever as people are looking to add ... National Love Your Produce Manager® Day is April 2. ...
(Date:3/26/2015)... March 26, 2015 North American Seminars ... website is dedicated to providing information regarding OT PT ... therapy community. As a leader in live hands ... provided over 200 live and online continuing education courses. ... Education Courses :, A Master Clinicians Approach to Advanced ...
Breaking Medicine News(10 mins):Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 2Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 3Health News:The World Does Not Have to Continue in Misery, Says Yisrayl Hawkins in New Article 2Health News:SoundsLikeIBS Nominated For 3rd Annual Scattergood Innovation Award 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 3
... RGDX ) today announced its President and CEO, ... on its ERCC-1,molecular diagnostic gene expression test for cisplatin-based ... Diego Marriot Del,Mar in San Diego October 31 to ... Thursday, Nov. 1. The presentation will be made ...
... NOGALES, Mexico, Oct. 31 Consejo de Latinos ... educates and,assists Latinos and others, and government officials ... news conference today the launch of an,international investigative ... 1st. Immigrant "dumping" is the practice of ...
... Provides Customized Oral Chemotherapy ... ... Maximizing on the momentum gained,during Breast Cancer Awareness Month, healthcare ... cancer patients --,OralChemoAdvisor.com -- an educational, state-of-the-art Web site about,oral ...
... shows that massage therapy decreases pain levels for patients after heart ... participated in a pilot study to examine the effect of massage ... mean pain scores were less than 1 on a scale of ... the massage therapy, these patients rated their pain at an average ...
... 31 Impact,Medical Solutions, Inc. (OTC Bulletin Board: ... of Craig W. Lunsman to its board,of directors. ... of William,Jamieson Group, LLC, a consulting group that ... and private small cap companies.,As an outside director, ...
... Top-Ranked Medicaid Plan in Pennsylvania, PITTSBURGH, Oct. 31 ... for Quality Assurance (NCQA) recently released its third,report on ... Plans 2007."* Gateway Health Plan is ranked #12 among ... in Pennsylvania. "Gateway Health Plan is extremely proud ...
Cached Medicine News:Health News:Response Genetics Announces Presentation/Webcast at BIOCOM Investor Conference 2Health News:Latino Advocacy Group Investigates Immigrant 'Dumping' by U.S. Employers 2Health News:Roche Offers Innovative Website Designed to Empower Cancer Patients 2Health News:Mayo researchers: complementary therapies help patients recover after heart surgery 2Health News:Mayo researchers: complementary therapies help patients recover after heart surgery 3Health News:Impact Medical Solutions Announces Appointment of New Director 2Health News:Impact Medical Solutions Announces Appointment of New Director 3Health News:Gateway Health Plan Ranked Again Among 'America's Best Health Plans' According to U.S. News & World Report, NCQA 2
(Date:3/26/2015)... 2015  Becton, Dickinson and Company (NYSE: BDX ... to exchange all validly tendered and accepted notes of ... owned subsidiary of BD, for notes to be issued ... Registration Statement on Form S-4 (the "Registration Statement") relating ... with the Securities and Exchange Commission ("SEC") on March ...
(Date:3/26/2015)... March 26, 2015 IGI Laboratories, Inc. (NYSE ... based specialty generic pharmaceutical company, today announced it has ... the U.S. Food and Drug Administration (FDA) of 2015, ... now pending at the FDA to twenty-three. ... Company, commented, "On March 2, 2015, we committed to ...
(Date:3/26/2015)...  Imagine a loved relative suffering from cancer - ... drugs are too expensive. The Austrian Centre of Industrial ... reduce production costs of highly valued drugs significantly. ... mercy of pathogens or cancer cells. Therapeutic antibodies are ... controlling autoimmune diseases such as multiple sclerosis. According to ...
Breaking Medicine Technology:Becton, Dickinson and Company to Commence Exchange Offers 2Becton, Dickinson and Company to Commence Exchange Offers 3Becton, Dickinson and Company to Commence Exchange Offers 4Becton, Dickinson and Company to Commence Exchange Offers 5IGI Laboratories, Inc. Announces First ANDA Submission Of 2015 2World's First Method for Continuous Purification of Valuable Antibodies 2
... company Apollo,Life Sciences has released results of preliminary ... tetanus,vaccine transdermally (through the skin) without the need ... Priest, the research points the way,to the possibility ... of the,past. , "With the winter months fast ...
... - Biofrontera AG announced,that an interim report regarding ... was received today from an independent review,committee. The ... and safety of several doses of BF-200 ALA ... the clinical results,eight weeks after treatment. An additional ...
Cached Medicine Technology:Apollo develops needle-free topical vaccine 2Apollo develops needle-free topical vaccine 3Apollo develops needle-free topical vaccine 4Apollo develops needle-free topical vaccine 5
Gerl tying forceps, titanium, with 0.12 mm teeth....
Castroviejo tying forceps, tying platforms, straight, 0.3 mm teeth....
Shepard tying forceps, round curved platform 8 mm, 8.5 cm....
Girard angled tying forceps made of titanium has angled 45 shafts with 4 mm tying platforms, width of shafts 0,25 mm, TCI platforms, round handle, diam. 6 mm, overall length 102 mm....
Medicine Products: