Navigation Links
Popular osteoporosis drugs triple risk of bone necrosis
Date:1/15/2008

A University of British Columbia and Vancouver Coastal Health Research Institute study has found that a popular class of osteoporosis drugs nearly triples the risk of developing bone necrosis, a condition that can lead to disfigurement and incapacitating pain.

The research is the largest study of bone necrosis and bisphosphonates, a class of drugs used by millions of women worldwide to help prevent bone fractures due to osteoporosis. It is also the first study to explore the link between bone necrosis and specific brands of bisphosphonates, such as Actonel, Didrocal and Fosamax. Researchers found that all three brands had similar outcomes.

Bone necrosis, a relatively rare disease diagnosed in approximately 1 in 20,000 people per year, leads to permanent loss of blood supply to the bones. Without adequate blood supply, the bone tissue dies and causes the bone to collapse. The disease primarily affects shoulders, knees and hips at the joints, causing severe pain and immobility.

Published online by the Journal of Rheumatology today, the findings follow a recent U.S. Food and Drug Administration alert about bisphosphonates that highlighted the possibility of severe and sometimes incapacitating bone, joint and/or muscle pain in patients taking the drugs. (To view the FDA alert, visit: http://www.fda.gov/cder/drug/infopage/bisphosphonates/default.htm.)

According to the American Dental Association, more than 190 million prescriptions have been written for bisphosphonates worldwide. The drugs are promoted in direct-to-consumer advertisements on U.S. television stations.

The message for women taking these medications is to pay attention to your pain, said principal investigator Dr. Mahyar Etminan of the Centre for Clinical Epidemiology and Evaluation at UBC and VCHRI. Given the widespread use of these drugs, it is important that women and their
'/>"/>

Contact: Basil Waugh
basil.waugh@ubc.ca
604-822-2048
University of British Columbia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007
2. Will Lipodissolve Continue to Remain Popular?
3. One-Third of Popular Songs Refer to Substance Abuse
4. Giant Eagle Expands Popular Generic Prescription Program and Now Offers 400 for $4
5. Banco Popular Commits To Make A Difference Day 2007
6. Study Rates Heart Health of Popular Diet Plans
7. HSA Plans Gain Popularity as Premium Costs Rise
8. Oral osteoporosis meds appear to reduce the risk of jaw degradation
9. Wyeth Receives Approvable Letter from FDA for Bazedoxifene for the Prevention of Postmenopausal Osteoporosis
10. Many Osteoporosis Medications Prevent Fractures, But None Is Proven Best
11. High-trauma fractures in older men and women linked to osteoporosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... Medicine scientists could lead to potential new treatments for ... scleroderma. , Fibrosis, or scarring, is a hallmark ... and lungs can lead to serious organ damage and, ... therapeutic options centers on findings made by Swati Bhattacharyya, ... role that a specific protein plays in promoting fibrosis. ...
(Date:4/17/2014)... chronic inflammation in non-cancerous prostate tissue may have nearly ... those with no inflammation, according to results of a ... Kimmel Cancer Center. , The link between persistent inflammation ... high-grade prostate cancer those with a Gleason score ... the most aggressive and rapidly growing prostate cancers. , ...
(Date:4/17/2014)... have identified new pain relief targets that could ... BBSRC-funded researchers at King,s College London made the ... in the periphery of the body. , Dr ... identifying mechanisms underlying pain generation and our findings ... side effects." , One potential side effect of ...
(Date:4/17/2014)... a study published today in PLOS Pathogens , ... malaria is common can mount an immune response to ... avoid repeated bouts of high fever and illness and ... bloodstream. The findings may help researchers develop future interventions ... malaria parasite. , Each year, approximately 200 million cases ...
(Date:4/17/2014)... University of California, San Diego School of Medicine report ... suffered a recent major loss are more likely to ... The study is published in this month,s issue of ... Because compassionate behaviors are associated with better health and ... into ways to improve the outcomes of individuals whose ...
Breaking Medicine News(10 mins):Health News:New clues on tissue scarring in scleroderma 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:New pain relief targets discovered 2Health News:Study sheds light on how the immune system protects children from malaria 2Health News:The ilk of human kindness 2
... film "Being Cyrus" coming up, the number of films// in ... sexual side has shot up once more. ,The made-in-Mumbai ... is attracted towards Cyrus, essayed by Saif Ali Khan. The ... the exception of a handful of movies like "Freaky Chakra", ...
... tobacco industry battle is// the health care costs. ... into high gear within two years. This info was provided ... said, "This will unfold in a stepwise fashion over the ... position to work with our colleagues in British Columbia and ...
... reported in Egypt, the most populous North African country. Laboratory ... died as a consequence of the highly pathogenic H5N1 strain ... in Qalyubiya, some 40 km north of here, died early ... treated for flu-like symptoms, the health ministry said in a ...
... easing their emotional pain by taking Oxycontin, a prescription painkiller. ... heroin as a cheaper option. // Michaud, now 18 ... getting addicted to prescription drugs. Teenagers are increasingly experimenting with ... online or taken from medicine cabinets. , Health ...
... the NHS on April 1. Dentists in England and Wales ... April 1st. // Several Cumbrian practices have already opted out. ... when leaving the NHS. ,But now due to ... days notice. The North Cumbria Primary Care Trusts (PCTs) cannot ...
... good news but there is a silver lining. Those children ... onset to develop kidney failure in adulthood.// ,This ... journal Diabetes Care. ,Dr. Maria Svensson, of Umea University ... from two nationwide registers, which include 12,032 cases of childhood ...
Cached Medicine News:Health News:Needed, more space for women's sexual identity on marquees 2Health News:Needed, more space for women's sexual identity on marquees 3Health News:Needed, more space for women's sexual identity on marquees 4Health News:New Generation Teenagers Addiction to Prescription Drugs 2
(Date:1/15/2014)... plc (LSE: SHP, NASDAQ: SHPG ) announces that it ... the announced tender offer for all of the outstanding shares of ... the waiver, the transaction is no longer conditional on OFT approval, ... 2014 following the currently scheduled expiration time, subject to the satisfaction ...
(Date:1/15/2014)... Tegra Medical is very pleased to announce the appointment ... Chief Executive Officer.  Mark was promoted from his current role ... company,s four facilities in Massachusetts , ... Tegra Medical in 2012 with 20+ years of broad-based operations, ...
(Date:1/15/2014)... Jan. 15, 2014 Reportlinker.com announces that ... in its catalogue: ... Analysis http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17
... Sustained Improvements in Blood Glucose,Control and Progressive ... /PRNewswire-FirstCall/ -- Amylin,Pharmaceuticals, Inc. and Eli Lilly ... that showed BYETTA(R) (exenatide) injection,sustained improvements in ... three and a half years of therapy. ...
... 25, 2007 /PRNewswire-FirstCall/ --,Phosphagenics Limited (AIM: PSG) announced ... dermal drug delivery,technology formulated with retinoic acid, a ... ingredient used in,anti-aging cosmetics. , The proof of ... of retinoic acid delivered into the skin when ...
Cached Medicine Technology:Byetta Treatment for Three and a Half Years Associated with,Reductions in Cardiovascular Risk Factors in People with Type 2,Diabetes 2Byetta Treatment for Three and a Half Years Associated with,Reductions in Cardiovascular Risk Factors in People with Type 2,Diabetes 3Byetta Treatment for Three and a Half Years Associated with,Reductions in Cardiovascular Risk Factors in People with Type 2,Diabetes 4Byetta Treatment for Three and a Half Years Associated with,Reductions in Cardiovascular Risk Factors in People with Type 2,Diabetes 5Byetta Treatment for Three and a Half Years Associated with,Reductions in Cardiovascular Risk Factors in People with Type 2,Diabetes 6Phosphagenics Announces Positive Proof of Concept Results from,Studies Utilizing Company's Dermal Drug Delivery Technology 2
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Medicine Products: