Navigation Links
Popular nanoparticle causes toxicity in fish, study shows
Date:3/2/2010

WEST LAFAYETTE, Ind. - A nanoparticle growing in popularity as a bactericidal agent has been shown to be toxic to fish, according to a Purdue University study.

Tested on fathead minnows ╨ an organism often used to test the effects of toxicity on aquatic life -- nanosilver suspended in solution proved toxic and even lethal to the minnows. When the nanosilver was allowed to settle, the solution became several times less toxic but still caused malformations in the minnows.

"Silver nitrate is a lot more toxic than nanosilver, but when nanosilver was sonicated, or suspended, its toxicity increased tenfold," said Maria Sepulveda, an assistant professor of forestry and natural resources whose findings were published in the journal Ecotoxicology. "There is reason to be concerned."

Sepulveda and doctoral student Geoff Laban exposed fathead minnows to nanosilver at several stages of their development, from embryo to the point where they swim up from the bottom of their habitats to eat for the first time. Even without sonication, nanosilver caused malformations that included head hemorrhages and edema, and ultimately proved lethal.

Using electron microscopy, Sepulveda was able to detect nanosilver particles measuring 30 nanometers or less inside the minnow embryos. Thirty nanometers is more than 3,000 times smaller than the diameter of a human hair.

"These nanosilver particles are so small they are able to cross the egg membranes and move into the fish embryos in less than a day," Sepulveda said. "They had a potentially high dose of silver in them."

Nanosilver is growing in popularity as a component of many products. It is used to kill bacteria in goods such as odor-control clothing, countertops, cutting boards and detergents. Currently, there are few regulations for nanosilver's applications in products, but Ron Turco, professor of agronomy and the paper's co-author, said the Environmental Protection Agency is reviewing the situation.

Turco also indicated there has been little work done to estimate the current level of nanosilver being released into the environment.

"Silver has been used in the past as an antimicrobial agent. It's a known toxicant to microorganisms," he said. "Nanosilver is being considered by the EPA for environmental exposure profiling, much like a pesticide."

Turco said it's unclear how nanosilver exposure might affect human health; however, he said that silver solutions have been considered by some to be a probiotic, and low dosages are sometimes consumed for intestinal health.

"The use of nanosilver could provide a number of sanitary benefits if used properly," Turco said. "However, the indiscriminate inclusion of nanosilver into products to simply allow them to say they are antimicrobial is creating a cautionary issue."

Sepulveda said she plans to develop tests to understand the effect different nanoparticles have on fish and other organisms. She also wants to develop testing to determine nanosilver concentrations in the environment.

"How are we going to know the risk unless we know the concentration of these particles?" Sepulveda said.


'/>"/>

Contact: Brian Wallheimer
bwallhei@purdue.edu
765-496-2050
Purdue University
Source:Eurekalert

Related medicine news :

1. HSA Plans Gain Popularity as Premium Costs Rise
2. Study Rates Heart Health of Popular Diet Plans
3. Banco Popular Commits To Make A Difference Day 2007
4. Giant Eagle Expands Popular Generic Prescription Program and Now Offers 400 for $4
5. One-Third of Popular Songs Refer to Substance Abuse
6. Will Lipodissolve Continue to Remain Popular?
7. Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007
8. Popular osteoporosis drugs triple risk of bone necrosis
9. Jan Marini Skin Research Suspends Sales of Popular Eyelash Products
10. Popular arthritis drug may disrupt heart rhythm, UB research finds
11. PetFirst: Pet Insurance To Be More Popular in 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... Mediaplanet today announces the launch ... lifestyles and highlighting the importance of proactive eye and ear health. The campaign ... latest innovations in hearing aid technology. , In this issue, the American ...
(Date:8/18/2017)... ... 18, 2017 , ... Radabaugh & Associates, a family managed ... North-Central West Virginia, is embarking on a cooperative charity effort with the Chestnut ... The Chestnut Mountain Ranch (CMR) is a Christ-centered boarding school for young men ...
(Date:8/18/2017)... ... August 18, 2017 , ... Goss & Associates Insurance Agency, ... commercial clients in the greater Houston region, is helping locally recognized nonprofit Addi’s ... against cancer. , Founded by Tony and Amber Bender after losing their young ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The ... says will lift the veil on false teachings pertaining to the mother of the Savior ... teach, you see a far different picture of the role of this historical woman. ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Our Mountains to Climb: A ... a couple that grew stronger together through the faith they shared to overcome struggles ... is the creation of published author, Barbara J. Corcoran, a retired teacher and happily ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... (NYSE: DPLO), the nation,s largest independent specialty pharmacy, announced financial ... unless otherwise noted, are to the quarter ended June 30, ... 2017 Highlights include: Revenue of $1,126 ... Total prescriptions dispensed of 220,000, compared to 241,000 ... Gross profit per prescription dispensed of $371, ...
(Date:8/4/2017)... , Aug. 3, 2017  Agragen, LLC, ... company active in the biopharmaceutical, nutraceutical, and aquacultural ... development of its lead drug candidates, AGR131.  This ... proinflammatory cytokine from the blood of patients suffering ... and inflammatory bowel disease. ...
(Date:8/2/2017)... , Aug. 2, 2017   Marshall County Hospital in Benton, Kentucky ... reduce the risk of hospital-acquired infections (HAIs). The new addition, Tru-D SmartUVC , short ... to kill deadly pathogens such as C. diff , MRSA, MERS, Ebola and more. ... Tru-D SmartUVC ... Tru-D in action in a patient room ...
Breaking Medicine Technology: