Navigation Links
Popular mammography tool not effective for finding invasive breast cancer
Date:7/27/2011

This release is available in Spanish.

Computer-aided detection (CAD) technology is ineffective in finding breast tumors, and appears to increase a woman's risk of being called back needlessly for additional testing following mammography, a large UC Davis study has found.

The analysis of 1.6 million mammograms in seven states has delivered the most definitive findings to date on whether the popular mammography tool is effective in helping find breast cancer.

"In real-world practice, CAD increases the chances of being unnecessarily called back for further testing because of false-positive results without clear benefits to women," said Joshua Fenton, assistant professor in the UC Davis Department of Family and Community Medicine. "Breast cancers were detected at a similar stage and size regardless of whether or not radiologists used CAD."

The study examined screening mammograms performed on more than 680,000 women at 90 mammography facilities in seven U.S. states from 1998 to 2006. The false-positive rate typically increased from 8.1 percent before CAD to 8.6 percent after CAD was installed at the facilities in the study. In addition, the detection rate of breast cancer and the stage and size of breast cancer tumors were similar regardless of CAD.

The study, entitled "Effectiveness of Computer-Aided Detection in Community Mammography Practice," was published online today in the Journal of the National Cancer Institute and used data from the Breast Cancer Surveillance Consortium.

Computer-aided detection software, approved by the Food and Drug Administration in 1998, analyzes the mammogram image and marks suspicious areas for radiologists to review. Its use has skyrocketed in recent years since Medicare began covering it in 2001. CAD is now applied to the large majority of screening mammograms in the U.S. with annual direct Medicare costs exceeding $30 million, according to a 2010 study in the Journal of the American College of Radiology.

According to 2009 Medicare data, insurers including Medicare typically paid about $12 per screening mammogram for CAD in addition to the costs of the mammogram (about $81 for film mammography and $130 for digital mammography), representing a 9 percent to 15 percent additional cost for CAD use.

The current study builds on Fenton's initial assessment of the technology published in the New England Journal of Medicine in 2007. That report, which examined mammography screening results in 43 facilities, including seven that utilized CAD, found that CAD was associated with reduced accuracy of interpretation of screening mammograms but no difference in the detection rate of invasive breast cancer.

Critics of the research findings in the New England Journal of Medicine said the study was based on use of an older kind of CAD technology, and so did not accurately reflect its usefulness.

"In the current study, we evaluated newer technology in a larger sample and over a longer time period," said Fenton. "We also looked for the first time at cancer stage and cancer size, which are critical for understanding how CAD may affect long-term breast cancer outcomes, such as mortality."

The authors write that the results of real-world studies of CAD may differ from results from pre-clinical studies. They suggest that these differences may arise because radiologists in clinical practice don't always adhere as strictly to use of the technology as designed, as have radiologists in protocol-driven studies.


'/>"/>

Contact: Dorsey Griffith
dorsey.griffith@ucdmc.ucdavis.edu
916-734-9118
University of California - Davis Health System
Source:Eurekalert

Related medicine news :

1. Internal bleeding higher with popular heart device than earlier model
2. Popular Blood Pressure Meds Not Linked to Cancer, FDA Says
3. Care for a spot of (green) tea? New NIST reference materials for popular diet supplement
4. Popular Heartburn Meds May Boost Fracture Risk
5. Contrary to popular belief, not all cases of chronic pancreatitis are alcohol-induced
6. Popular Baby Media May Not Actually Advance Learning
7. Popular drugs for common male health problems can affect their sexual health
8. Popular Bone Drugs Linked to Reduced Colon Cancer Risk
9. Bullying May Accompany Drive to Be Popular
10. Zebrafish popular with researchers
11. Tanning Beds Still Popular Despite Skin Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... ... May 25, 2016 , ... CloudLIMS, joins an elite ... Life Sciences Tech Solution Providers list of 2016 by CIOReview. , In a deliberate ... Life Sciences Tech Solution Providers 2016 has been concluded with. The positioning is based ...
(Date:5/25/2016)... ... May 25, 2016 , ... Cheryl Bowker of Bowker Insurance Group ... Dick McKenna Good Hands Legacy Award. McKenna ran one of Allstate’s most successful agencies ... inspire all those who knew him. The award named for him is not given ...
(Date:5/25/2016)... ... May 25, 2016 , ... Afrimesure specializes in providing clients ... to food and HVAC facilities. Their knowledgeable staff also takes care of the ... applications, Afrimesure offers a variety of MadgeTech systems available for sterilization and temperature ...
(Date:5/25/2016)... ... May 25, 2016 , ... Conrad ... annual Medical and Prescription Drug survey , an employee benefits ... which was conducted in December 2015, indicates that employers are turning to consumer ...
(Date:5/25/2016)... (PRWEB) , ... May 25, 2016 , ... For more than fifty years, we've suffered ... we changed our diets to conform to the latest nutritional advice – advice that was ... the NIH, more than 2 in 3 American adults are considered to be overweight and ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... , May 24, 2016 Cirujanos ... para ayudar a los médicos a compartir sus mejores ... a escala mundial. Profesionales médicos de Europa, África, ... han apuntado a la aplicación, que combina la transmisión ... entorno totalmente seguro. Educación   "Imagine ...
(Date:5/24/2016)... , May 24, 2016  Diana Russell suffers from ... organs from the inside out.  This disease has put ... on her children and grandchildren to leave her home.  ... Diana,s family cannot haul the wheelchair.  So if there ... car, and Diana is left to wait for the ...
(Date:5/24/2016)... May 24, 2016 Celsion Corporation (NASDAQ: ... company, today provided an update on its ongoing ... trial combining GEN-1, the Company,s DNA-based immunotherapy, with ... newly-diagnosed patients with advanced ovarian cancer who will ... GEN-1 is an IL-12 DNA plasmid vector formulated ...
Breaking Medicine Technology: