Navigation Links
Popular diabetes drug does not improve survival rates after cancer: Study
Date:5/9/2013

TORONTO, ON, May 9, 2013 Despite previous scientific studies that suggest diabetes drug metformin has anti-cancer properties, a new, first-of-its-kind study from Women's College Hospital has found the drug may not actually improve survival rates after breast cancer in certain patients.

The study, published in the journal Diabetes Care, failed to show an improved survival rate in older breast cancer patients with diabetes taking the drug metformin, a first-line treatment for diabetes. However, the authors caution further research is necessary to validate the study's findings.

"Metformin is a drug commonly used by diabetic patients to control the amount of glucose in their blood," said the study's lead author Dr. Iliana Lega, a research fellow at Women's College Research Institute. "Although existing scientific literature suggests that drug may prevent new cancers and death from breast cancer, our study found the drug did not significantly impact survival rates in our patients."

Scientific research has found metformin is associated with an up to 30 per cent reduction in new cancers and a reduction in tumour growth in non-diabetic breast cancer patients treated with the drug, Dr. Lega notes in the study.

To test the drug's anti-cancer properties, the authors examined 2,361 women, aged 66 or older who were treated with the drug and diagnosed with breast cancer between April 1, 1997 and March 31, 2008. The women were followed from their date of breast cancer diagnosis until their death or until March 30, 2010. The researchers found no significant statistical correlation between cumulative use of metformin and death from all causes or a significant reduction in deaths due to breast cancer.

"What makes our study so unique is that while the effects of metformin have been well documented, previous research has not examined the cumulative effects of the drug on patients, particularly breast cancer patients with diabetes," Dr. Lega said. "This is important given that diabetic patients may switch drugs over the course of their treatment."

The authors note a lack of data on body mass index, breast cancer stage and a short followup period for breast-cancer specific deaths, limit interpretation of their findings. Further research is necessary in a younger population of patients with breast cancer and diabetes.

"Understanding the effects of metformin on breast cancer patients is critical in helping address the gap in cancer outcomes in patients with and without diabetes," she added. "The findings will help physicians inform treatment plans for patients with diabetes."


'/>"/>

Contact: Julie Saccone
julie.saccone@wchospital.ca
416-323-6400 x4054
Women's College Hospital
Source:Eurekalert

Related medicine news :

1. Popular Medical Tourism Blog Gets a Makeover
2. Results of Recent Poll Show Shorter Vacations and Long Weekends Fast Becoming a Popular Trend in Vacations for Crystal Travel Center Members in Westlake Village
3. NewsWatch, a National Television Show, Recently Aired a Segment Featuring I, Gladiator, a Popular Swipe Battle Game for iOS Mobile Devices
4. Study Reveals L-Carnitine, Which is Found in Popular Weight Loss Supplement Liproxenol, Lowers Risk of Death From All Causes
5. 100% Pure Garcinia Cambogia Extract So Popular It's Selling Out; Alphatrition Now Offering 25% off While Supplies Last
6. Impact with Martin Sheen Exploring Recycling Popularity in New Report
7. Nouvelle Presents Summer Bras for Use after Popular Breast Augmentation Surgery
8. Popular Cinnamon Stunt Can Have Serious Lung Effects
9. Scheduling Software, Mobile App Popularity Up as Personal Training Industry Grows, According to Appointment-Plus
10. Newly Updated Fact Sheet Suggests that Vitamin B6, Which is Found in Popular Weight Loss Supplement Liproxenol, May Ease Carpal Tunnel Syndrome
11. Rap Star’s Hospitalization Spotlights the Dangerous Popularity of “Purple Drank,” advises Passages Malibu
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... ... the #perioddrama campaign to mark Menstrual Hygiene Day on May 28 and raise awareness of ... have access to a toilet, even when they’re on their periods. , WaterAid asked over ... results help shine a light on the awkwardness that women face while menstruating, even in ...
(Date:5/24/2016)... MA (PRWEB) , ... May 24, 2016 , ... ... Harvard Medical School, today announced a licensing relationship that will deliver a new ... This relationship will put the medical knowledge and expertise of Harvard Medical ...
(Date:5/24/2016)... (PRWEB) , ... May 24, 2016 , ... ... of safety signs and safety labels , has been featured ... Symbols: Laser Labels.” , The eiXtra e-newsletter provides electroindustry professionals with manufacturer, regulatory, ...
(Date:5/24/2016)... Conn. (PRWEB) , ... May 24, 2016 , ... After ... . He spent the next decade in hospitals, on medication, living on Social Security ... Look at the Illness and How I Beat It!” (published by Balboa Press), Alexander ...
(Date:5/24/2016)... ... May 24, 2016 , ... Design Concepts , ... Centro del Quinto Sol Wheel Park’ in Pueblo, Colorado. This park was designed ... something special for this often overlooked neighborhood. Located at 609 E. 6th Street, ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... The World Health Organization (WHO) expanded the Intended ... adolescents aged 13 years, and above. Effective immediately, the PrePex ... and adolescent males in the 14 priority countries in Southern ... first male circumcision device to receive WHO Prequalification on 31 ... said: " The expanded use of PrePex ...
(Date:5/23/2016)... -- Gamida Cell, a leader in cellular ... orphan genetic diseases, announced today it has been awarded ... Israel Innovation Authority (formerly the Office of the Chief ... The mission of the Israel Innovation Authority is to ... and technology, while stimulating economic growth. The ...
(Date:5/22/2016)... DUBLIN , May 23, 2016 ... to develop its anti-fibrotic and anti-inflammatory compound DS102 ... well as in non-alcoholic steatohepatitis (NASH) patients. ... is significantly sequestered in lung tissue and has ... tissue after oral administration. The Company will publish ...
Breaking Medicine Technology: