bserved in two of the 12 patients in the study suggest that curcumin may have promise for a small subset of patients with psoriasis. Large, placebo-controlled trials are necessary to definitively prove or disprove oral curcumin as a potential therapeutic agent for psoriasis. What is needed is scientific data to assess the safety and efficacy of these treatments so that we may more rationally inform patients of their treatment options, says Gelfand.