Navigation Links
Popular alternative therapy for psoriasis performs no better than placebo
Date:2/29/2008

Anecdotal evidence touting the healing power of the Indian spice turmeric for psoriasis received a setback in a prospective study published this month by a leading dermatology journal stating that the low response rate of patients who ingested the active ingredient of the exotic spice was probably a result of the placebo effect.

Researchers at the University of Pennsylvania School of Medicine found that despite strong scientific evidence in the laboratory demonstrating the ability of curcumin (the active ingredient in the spice turmeric) to inhibit a critical pathway of psoriasis, the positive response in patients was so low that scientists suggest the placebo effect or the diseases natural remission might be the reason. The study was published in the Journal of the American Academy of Dermatology.

Alternative and complementary websites and newspapers publish anecdotal reports that the Indian spice has been successfully used to treat psoriasis, says Joel M. Gelfand, MD, MSCE, of The University of Pennsylvania School of Medicine. However, spontaneous improvements in psoriasis are common, and based on our study, until larger, placebo-controlled trials are conducted, oral curcumin should not be recommended for the treatment of psoriasis given lack of proven efficacy.

But the researchers do not discount entirely the potential of curmumin as a treatment for psoriasis.

They recognize that current traditional pharmacologic approaches in the treatment of psoriasis are costly and have their limitations, including the risk of infections and possibly malignancies with long-term use resulting in many patients with the disease unable to achieve effective long-term control. Turning to complementary and alternative therapies is understandable, they say. In fact, of the estimated 7 million diagnosed with psoriasis, it is estimated that 51% use complementary and alternative medicine therapies to treat their skin.

The excellent responses that were observed in two of the 12 patients in the study suggest that curcumin may have promise for a small subset of patients with psoriasis. Large, placebo-controlled trials are necessary to definitively prove or disprove oral curcumin as a potential therapeutic agent for psoriasis. What is needed is scientific data to assess the safety and efficacy of these treatments so that we may more rationally inform patients of their treatment options, says Gelfand.


'/>"/>

Contact: Marc Kaplan
marc.kaplan@uphs.upenn.edu
215-662-2560
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Despite popularity, researcher finds not everyone can successfully learn through online courses
2. Small-Diameter Dental Implants Increasingly Popular In the US
3. Two Little Hands Productions, Creators of Popular Childrens TV Series Signing Time, Debuts Second Season at This Years Toy Fair 2008
4. Popular Florida Restaurant Leads Hospitality Industry by Converting to Pasteurized Shell Eggs Usage
5. PetFirst: Pet Insurance To Be More Popular in 2008
6. Popular arthritis drug may disrupt heart rhythm, UB research finds
7. Jan Marini Skin Research Suspends Sales of Popular Eyelash Products
8. Popular osteoporosis drugs triple risk of bone necrosis
9. Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007
10. Will Lipodissolve Continue to Remain Popular?
11. One-Third of Popular Songs Refer to Substance Abuse
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... ... May 26, 2016 , ... Metcalf & Associates’ ... years of experience in leading technology and human resources operations for health care, ... Morrow-Fox will be featured on Metcalf’s VoiceAmerica radio show , Innovative Leaders ...
(Date:5/26/2016)... ... May 26, 2016 , ... Dr. LeRoy Perry’s recently authored whitepaper, ... mobile devices on the billions of users, hundreds of millions of whom are coming ... life threatening, the frequent and common action of looking down at hand-held technology devices ...
(Date:5/26/2016)... ... May 26, 2016 , ... Development Team of Pixel Film Studios ... , "This new layered style transition tool will keep a consistent flow to your ... Pixel Film Studios. , TranSweep is an all new layered style transition tool ...
(Date:5/26/2016)... ON (PRWEB) , ... May 26, 2016 , ... ... Organization, is proud to announce that it has successfully completed another Health Canada ... Branch Inspectorate of Health Canada. The rating resulted from a Good Manufacturing Practices ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... weekend to host their second pop-up shop for three consecutive weekends. The pop-up ... to the Santa Barbara community, a community full of women who appreciate the ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... Zealand , May 24, 2016 ... informatics solutions for the healthcare sector, has been named the ... Zealand Hi-Tech Awards 2016. Dr Bruce Davey ... acknowledgement for our team.  It,s really good to be recognised ... healthcare internationally. Our products are used in 35 countries around ...
(Date:5/24/2016)... , May 24, 2016 Celsion ... drug development company, today provided an update on ... escalating clinical trial combining GEN-1, the Company,s DNA-based ... treatment of newly-diagnosed patients with advanced ovarian cancer ... debulking surgery.  GEN-1 is an IL-12 DNA plasmid ...
(Date:5/24/2016)... 2016 The innovator of ... , s first dual therapy stent, introduces catheters ... OrbusNeich, a global company specializing in the provision ... include products to treat peripheral artery disease. The JADE™ ... devices for lower limb and arteriovenous (AV) fistula intervention. ...
Breaking Medicine Technology: