Navigation Links
Poorly understood cell plays role in immunity against the flu
Date:3/22/2010

Boston, Mass. A new understanding of a certain cell in the immune system may help guide scientists in creating better flu vaccines, report researchers from the Program in Cellular and Molecular Medicine and the Immune Disease Institute at Children's Hospital Boston (PCMM/IDI). Reporting online March 21 in Nature Immunology, they show, for the first time, that white blood cells known as resident dendritic cells (DCs) capture flu viruses and show them to B-lymphocytes, another white blood cell that recognizes germs and launches an antibody attack. Harnessing this previously unknown function could help activate the immune system more effectively against the flu virus.

"The government is putting a lot of money into vaccine development," says senior investigator Michael Carroll, PhD, director of the immunology graduate program at PCMM/IDI. "A lot of people are thinking about how to target vaccines, and this kind of information will tell us what cell type we would want to target."

Carroll's lab, in collaboration with Shannon Turley of the Department of Cancer Immunology and AIDS at Dana Farber Cancer Institute and Department of Pathology, Harvard Medical School, closely examined what happens when a flu vaccine is injected into mice, a good model for human vaccination. They focused specifically on what happens in the lymph node, where germs and vaccine antigens are filtered.

"We're trying to break down this black box that we know as the lymph node, and identify the different cells that are there, how they interact with each other and what the general rules are," Carroll says. "Then, you can begin to manipulate it to improve vaccines and immune responses."

When it comes to building permanent immunity, B-lymphocytes are the key players because they can remember specific germs and mount a rapid antibody attack. One way B-lymphocytes first encounter germs in the lymph nodes is through the help of macrophages, white blood cells t
'/>"/>

Contact: Erin McColgan
erin.mccolgan@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Long-acting beta-agonists most effective step-up therapy for children with poorly controlled asthma
2. AGH Study Shows High Rates of Poorly Controlled Asthma Among Inner-City Pittsburgh Children
3. Alcoholics Relapses Better Understood
4. Autism-Related Hypersensitivity Better Understood
5. Genital Herpes Reactivation Better Understood
6. Breast Cancers Spread Now Better Understood
7. Visual Processing Plays Role in Body Dysmorphic Disorder
8. Amerigroup Plays Key Role in Fraud Conviction
9. Playground Surface Plays a Role in Kids Injuries
10. Study Details Machinery of Immune Protection Against Inflammatory Diseases Like Colitis
11. Selenium Could Shield Against Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... gluttons. We have long known that they monopolize large ... some tumor cells are also characterized by a series ... in an ordered set. Researchers are calling this behavior ... EPFL, Etienne Meylan,s research team was able to demonstrate ... mesenchymal behavior result from the same mechanism, at ...
(Date:7/28/2014)... July 29, 2014 The ... Situ Hybridization, Digital pathology & Workflow, Special ... Prostate Cancer, Non Small Cell Lung Cancer ... (Hospitals, Pharmaceutical companies, Research Laboratories, Contract Research ... Americas, Europe, BRIC, Japan & RoW) - ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 A lush green ... playtime during the summer. However, the summer heat, lack of ... to become brown, weak and unhealthy. The Grounds Guys recommends ... Grow, Mow a lawn once a week and set the ... normal. This protects the grass roots from heat and allows ...
(Date:7/28/2014)... UHY LLP, a member of the ... UHY International Business – Issue 29. This bi-annual publication ... most current business challenges and key issues faced by ... the following topics:, , Key industry ... over the next five years? Where are growth opportunities ...
(Date:7/28/2014)... Dawn Echols’ professional background spans success in ... experience has honed her people skills and led ... counseling ( http://dawningphoenix.com ) work includes private practice, ... domestic violence. , As owner and executive ... individuals and groups for a variety of disorders. ...
Breaking Medicine News(10 mins):Health News:Cancer: Tumors absorb sugar for mobility 2Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 2Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 3Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 4Health News:Advanced Cancer Diagnostics Market Worth $3,924.01 Million by 2018 - New Report by MarketsandMarkets 5Health News:Nurturing Lawns in the Summer Heat: The Grounds Guys® Offers Tips on Caring for Lawns This Summer 2Health News:Uhy International Business Issue 29 Now Available 2Health News:Uhy International Business Issue 29 Now Available 3Health News:Dawn M. Echols, M.S., LPC of Dawning Phoenix Speaks at Newly Formed Task Force 2
... Keynote Afternoon Session on Legal, Regulatory and,Policy Issues, ... healthcare in the United States?, That,s a ... national conference,Personalized Medicine: Promises and Challenges, sponsored by ... and the Food and Drug Law,Institute (FDLI), June ...
... launching a communications revolution, cell phones are talking up ... use of telecommunications technology to provide medical diagnosis and ... thousands of miles apart. Researchers in the United States ... system that uses ordinary cell phone cameras to collect ...
... joins The Libby Ross Foundation to ... unveil celebrity-designed yoga bags, NEW YORK, May 5 ... Ross Foundation to help empower women,battling breast cancer through the charity,s ... has joined the,cause to raise funds for this unique program by ...
... Access to Educational Programming to Promote Stroke Awareness ... Prevention during Stroke Awareness ... and,Comcast have partnered to raise awareness and understanding of the ... through Comcast,s ON DEMAND service. Throughout the month of May,in ...
... a leading healthcare,communications network, announced that Michel Nakache has ... will join Doug Burcin and Donna,Murphy as a Worldwide ... "We,re thrilled to have Michel back at Euro ... a perfect fit for our growing agency,",said Burcin. "Michel,s ...
... new organic 0% fat Greek yogurt flavors to ... satisfy consumers, hungry demands, ... organic yogurt-maker, is expanding the flavor offerings of its,organic, authentically ... yogurts join the Oikos Organic line of,0% fat favorites, Vanilla ...
Cached Medicine News:Health News:AAAS, FDLI Sponsor Landmark Meeting on Personalized Medicine June 20, 2008 2Health News:AAAS, FDLI Sponsor Landmark Meeting on Personalized Medicine June 20, 2008 3Health News:Talking up a new role for cell phones in telemedicine 2Health News:Celebrity Mothers and Daughters Including Miley and Trish Cyrus Join Swarovski to Support Breast Cancer Survivors 2Health News:The American Heart Association and Comcast Team Up to Strike Out Stroke 2Health News:The American Heart Association and Comcast Team Up to Strike Out Stroke 3Health News:Michel Nakache Returns to Euro RSCG Life as Worldwide Managing Partner 2Health News:Oikos Organic Greek Yogurt Ventures into the Land of Milk and Honey ... and Blueberry! 2Health News:Oikos Organic Greek Yogurt Ventures into the Land of Milk and Honey ... and Blueberry! 3
(Date:7/28/2014)... 28, 2014 KaloBios Pharmaceuticals, Inc. (Nasdaq: ... status of the KB001-A development program, including an update ... KB001-A Collaboration Update KaloBios announced ... to regain all rights to KaloBios, KB001-A program. Under ... in 2010 has been terminated. Under that collaboration agreement, ...
(Date:7/28/2014)...  Serco Inc., a provider of professional, technology, ... awarded a re-compete contract to support the Navy ... Medical Systems.  Serco will provide deployable medical systems ... healthcare to meet warfighter and humanitarian requirements in ... five year contract has a one-year base period ...
(Date:7/28/2014)... 2014  Array BioPharma Inc. (Nasdaq:   ARRY) ... quarter and full year of fiscal 2014 ... those results on Tuesday, August 12, 2014.  ... Michael Carruthers , Chief Financial Officer will ... 2014Time:9:00 a.m. Eastern TimeToll-Free:(800) 708-4540Toll:(847) 619-6397Pass Code: ...
Breaking Medicine Technology:KaloBios Provides Update on KB001-A Partnership and Clinical Status 2KaloBios Provides Update on KB001-A Partnership and Clinical Status 3KaloBios Provides Update on KB001-A Partnership and Clinical Status 4KaloBios Provides Update on KB001-A Partnership and Clinical Status 5KaloBios Provides Update on KB001-A Partnership and Clinical Status 6Serco Awarded $22.7 Million Contract to Support Deployable Medical Systems 2
... In response to a report recently issued by the ... rising death toll from prescription painkiller overdose, Reckitt Benckiser ... to learn more about the disease of addiction, available ... www.TurnToHelp.com . The new CDC ...
... International, Inc. (NYSE: VRX ) (TSX: VRX) ... to the role of Executive Vice President and Chief ... Valeant, which is expected to be December 1, 2011. ... he was the chief operating officer for the Investment ...
Cached Medicine Technology:New Report Puts Spotlight on Epidemic of Painkiller Abuse and Need for Patient Education and Resources 2Valeant Pharmaceuticals Appoints Howard B. Schiller as Chief Financial Officer 2Valeant Pharmaceuticals Appoints Howard B. Schiller as Chief Financial Officer 3
TeleRehab Advantage is a monitoring system that automates the generation of outcomes data. Patient information and session information is automatically transferred from the monitoring program to Outc...
... Clearly, the ISI Lexan ... versatile surgical table for lower ... orthopaedic, head and neck, and ... optional traction package gives you ...
MagaCell-Streptavidin is a streptavidin coupled to magnetizable cellulose/iron oxide particles...
Streptavidin A-Beads are polydisperse 1.8 m paramagnetic particles covalently coupled with streptavidin. The paramagnetic particles remain in solution over extended periods of time. Mixing is require...
Medicine Products: