Navigation Links
Poor sleep quality leads to poorer prognosis after stroke
Date:4/28/2009

Stroke victims tend to do worse if they also have diagnosed or undiagnosed obstructive sleep apnea prior to having the stroke, according to a study presented April 28, 2009, at the American Academy of Neurology (AAN) annual meeting in Seattle.

Latha Stead, M.D., professor and chair of the Department of Emergency Medicine at the University of Rochester Medical Center, and professor of Neurosurgery, reported the findings at AAN, along with several other stroke studies measuring the factors that lead to a poor prognosis.

"We know that obstructive sleep apnea has been linked to a multitude of cardiovascular problems, yet it is concerning that the vast majority of cases remain undiagnosed," Stead said. "In the context of recovering from a stroke, sleep apnea can have a serious impact, and for that reason we encourage people to become more aware of obstructive sleep apnea and to get treatment."

The prospective study included 174 patients who were diagnosed with an acute ischemic stroke in the emergency department at the Mayo Clinic between June 2007 and March 2008. (Stead was the inaugural chair of the Division of Emergency Medicine Research at Mayo before recently joining the URMC.) The stroke-sleep study was conducted in collaboration with Virend Somers, M.D., Ph.D., who is well known for his work in sleep apnea.

Researchers used a standard questionnaire to assess the risk of sleep apnea among all 174 patients, sometimes aided by the patients' sleep partners. They found that 60 percent were at high risk of sleep apnea, seven patients had a previous diagnosis of sleep apnea, and those seven patients had a higher risk of death within the first month following the stroke.

After adjusting for age and stroke severity, researchers also found that high risk of obstructive sleep apnea was a predictor of having a worse outcome. Stroke patients with diagnosed or undiagnosed sleep apnea were also more disabled at the point of discharge from the hospital. Other studies have shown similar results, Stead said, but the latest research included a larger sample size compared to earlier studies.

Strokes are the third leading cause of death and the leading cause of disability in the United States. Since sleep apnea is a breathing disorder associated with the collapse of the pharyngeal airway, it causes potentially dangerous fluctuations in blood pressure.

Researchers do not know the exact mechanisms associated with sleep apnea and poorer outcomes following a stroke. But Stead noted it is more difficult for the brain and related tissue to heal when blood is not properly oxygenated during a disrupted sleep cycle. Furthermore, patients do not respond well to stroke rehabilitation programs when they are repeatedly sleep deprived.

"The next step," she said, "is to begin routine screening for obstructive sleep apnea as part of the emergency department evaluation of stroke patients."

Stead and research colleagues also presented a study at AAN showing that high blood sugar, or hyperglycemia, is another predictor of early death following a stroke. While other studies have shown that diabetics face poorer outcomes after a stroke, this study focused on non-diabetics or undiagnosed diabetics who had higher-than-normal blood sugar levels in the emergency department.

"The important message is that in the Emergency Department setting, it's critical to investigate all of the known risk factors that indicate a poor prognosis following a stroke," Stead said. Other known risk factors include low blood pressure and irregular heart rhythm.

Stead's research is funded by a Mayo Foundation Emergency Medicine Research Career Development Award.


'/>"/>

Contact: Leslie Orr
Leslie_Orr@urmc.rochester.edu
585-275-5774
University of Rochester Medical Center
Source:Eurekalert

Related medicine news :

1. Simmons Celebrates Earth Day by Encouraging Consumers To "Sleep Green"
2. Too much or too little sleep increases risk of diabetes
3. Scent To Sleep All Natural Non-Drowsy Sleep Mist Acquired by Innovative Custom Products, Inc. (ICP)
4. Circadiance Launches the New SleepWeaver(TM) ADVANCE All Cloth CPAP Mask
5. Melatonin May Ease Sleep Problems in Autistic Children
6. Sleep May Be Cause, Not Consequence, of Cancer Issues
7. New way to analyze sleep disorders
8. Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms
9. Study suggests that trouble sleeping leads to increased ratings of pain in cancer patients
10. Melatonin is an effective treatment for sleep problems in children with autism
11. A $25 Sleeping Bag Incubator to Join More Than 40 Innovations at Extremely Affordable Health Innovations News Conference and Exhibit at 6th Annual World Health Care Congress, April 15, 2009
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... (PRWEB) , ... August 18, 2017 , ... Alcovit, a ... to ramp up its marketing efforts with its product now available through Jet.com. ... to the public. The effervescent powdered drink is designed to quickly detox the body ...
(Date:8/18/2017)... ... ... “Our Mountains to Climb: A Journey of Love and Faith Through Trials”: ... faith they shared to overcome struggles in life. “Our Mountains to Climb: A Journey ... Corcoran, a retired teacher and happily married since 1999; the author’s personal experiences drive ...
(Date:8/18/2017)... ... ... “Beyond Our Imaginations: The Infinite God”: shows the importance of God in living ... of published author, Mark Lawrence, born in Michigan, the author has lived in various ... greater man of God is that I have to be more mindful of feminine ...
(Date:8/18/2017)... ... ... Mandate for Kingdom Builders”: a call to walk as citizens of the Kingdom and ... published author, John F. McGeorge, Jr. Dr. John F. McGeorge Jr., B.A., J.D., ... three decades training pastors and Christian leaders. He also met his wife, Valerija, ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... , Aug. 7, 2017  Endo International plc ... reached agreements to resolve virtually all known U.S. mesh ... discussions to resolve the known remaining U.S. claims at ... payments beginning in the fourth quarter of 2017 and ... of its second quarter 2017 results, the Company intends ...
(Date:8/4/2017)... Aug. 3, 2017  Agragen, LLC, a ... in the biopharmaceutical, nutraceutical, and aquacultural feed sectors, ... its lead drug candidates, AGR131.  This drug is ... from the blood of patients suffering from inflammatory ... bowel disease. ...
(Date:8/2/2017)... Aug. 2, 2017 Fenita J. ... as a Pinnacle Lifetime Professional in the Field ... Manager at Turing Pharmaceuticals, AG. Her skills and ... relationship building.                ... 25 years of experience as a highly successful ...
Breaking Medicine Technology: