Navigation Links
Poor sleep more dangerous for women
Date:3/10/2008

DURHAM, NC Researchers at Duke University Medical Center say they may have figured out why poor sleep does more harm to cardiovascular health in women than in men.

Their study, appearing online in the journal Brain, Behavior and Immunity, found that poor sleep is associated with greater psychological distress and higher levels of biomarkers associated with elevated risk of heart disease and type 2 diabetes. They also found that these associations are significantly stronger in women than in men.

This is the first empirical evidence that supports what we have observed about the role of gender and its effects upon sleep and health, says Edward Suarez, an associate professor in the department of psychiatry and behavioral sciences at Duke and the lead author of the study. The study suggests that poor sleep measured by the total amount of sleep, the degree of awakening during the night, and most importantly, how long it takes to get to sleep may have more serious health consequences for women than for men.

Suarez says that while women are twice as likely as men to report problems with sleep, most sleep studies in the past have focused on men, a phenomenon that has been slowly changing in recent years.

Researchers studied 210 apparently healthy, middle-aged men and women without any history of sleep disorders. None smoked or took any medications on a daily basis and investigators excluded any women who were on hormone therapy, which has been shown in some studies to alter sleep patterns in some women.

Using a standardized sleep quality questionnaire, participants rated various dimensions of their sleep during the previous month. Additional measures assessed the extent of any depression, anger, hostility and perceived social support from friends and family.

Blood samples taken from the volunteers were measured for levels of biomarkers associated with increased risk of heart disease and diabetes, including insulin and glucose levels, fibrinogen (a clotting factor) and two inflammatory proteins, interleukin-6 and C-reactive protein.

The researchers found that about 40 percent of the men and the women were classified as poor sleepers, defined as having frequent problems falling asleep, taking 30 or more minutes to fall asleep or awakening frequently during the night. But while their sleep quality ratings were similar, men and women had dramatically different risk profiles.

We found that for women, poor sleep is strongly associated with high levels of psychological distress, and greater feelings of hostility, depression and anger. In contrast, these feelings were not associated with the same degree of sleep disruption in men, says Suarez.

Women who reported higher degree of sleep disruption also had higher levels of all the biomarkers tested. For women, poor sleep was associated with higher levels of C-reactive protein and interleukin-6, measures of inflammation that have been associated with increased risk of heart disease, and higher levels of insulin. The results were so dramatic that of those women considered poor sleepers, 33 per cent had C-reactive protein levels associated with high risk of heart disease, says Suarez.

Interestingly, it appears that its not so much the overall poor sleep quality that was associated with greater risk, but rather the length of time it takes a person to fall asleep that takes the highest toll, says Suarez. Women who reported taking a half an hour or more to fall asleep showed the worst risk profile.

The study was supported by a grant from the National Institutes of Health.

Suarez says hes planning further studies to understand the complex relationship between health risk and poor sleep in men and women. He believes that the gender differences may be due, in part, to variation in the activity of a number of naturally occurring substances in the body, such as tryptophan, an amino acid; serotonin, a neurotransmitter; and melatonin, a neurohormone. All of these substances are known to affect mood, sleep, onset of sleep, inflammation and insulin resistance, he says.

Good sleep is related to good health. More research needs to be done to define gender-linked responses to poor sleep, including the role that sex hormones play over a lifetime and how sleep needs and responses change from childhood to maturity, says Suarez.


'/>"/>

Contact: Michelle Gailiun
michelle.gailiun@duke.edu
919-660-1306
Duke University Medical Center
Source:Eurekalert

Related medicine news :

1. Physicians Say They Need More Sleep
2. Dallas Dentist Trains Navy Dentists on New Therapy to Treat Snoring and Obstructive Sleep Apnea
3. Sleep Medicine Associates Opens New Doors at Swedish - Cherry Hill Campus
4. Select Comfort Helps Families Sleep Better in Los Angeles
5. Figure Skater Peggy Fleming Teams With HealthSaver: Healthy Sleep Tips for a New You in 2008
6. Physicians report they need more sleep
7. Americans Sleepier Than Ever
8. TV Could Be Disrupting Your Kids Sleep
9. New Sleep Diagnostic Center Opens at Methodist Mansfield
10. Children who do not get enough sleep sustain more injuries
11. Airplane Noise Boosts Blood Pressure Even During Sleep
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... ... ... A prescription medication bottle, pocket knife, luggage and a solar-powered aluminum casting process ... , the Cradle to Cradle Products Innovation Institute has announced. , This ... through early 2018. The challenges are presented by the Institute in partnership with Autodesk ...
(Date:1/17/2017)... ... January 17, 2017 , ... SC&H Group, a leading audit, tax, and consulting ... IT Advisory Services practice . Rossi is the third technology consulting leader to ... IT guidance grows, and the practice continues to expand.     , Bringing more than 25 ...
(Date:1/17/2017)... ... 17, 2017 , ... The Sharie Withers Agency, a full-service ... latest beneficiary of their thriving community involvement program. The current campaign fundraises to ... dreams of terminally ill patients. Donations to this worthy cause may now be ...
(Date:1/17/2017)... ... January 17, 2017 , ... Twelve (12) years ago ... Training Education program forged a relationship built upon the foundation of sports safety. ... consists of both student members and certified members of the Athletic Trainers’ Society ...
(Date:1/16/2017)... ... January 16, 2017 , ... Gym Source, America’s leading retailer of premium residential ... Hanover, New Jersey. , “We are elated to be opening this new showroom,” explains ... designed to give clients a seamless and motivating shopping experience.” , Every fitness journey ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)...  In a letter to President-elect Donald J. ... outlines AARP,s priorities for Americans age 50 and older ... affordable health care coverage, and lowering the cost of ... to President-elect Trump that "Our nearly 38 million members ... to protect their Medicare and Social Security benefits, protect ...
(Date:1/17/2017)... 17, 2017  In a preview of the upcoming Society ... Astute Medical, Inc., developer of the NephroCheck Test, today highlighted ... identifies hospital patients at risk of developing moderate to severe ... month at the Hawaii Convention Center ... January 25. AKI is one of the top ...
(Date:1/17/2017)... Research and Markets has announced the addition of the "The ... ... identifies and profiles the leading 200 manufacturers and distributors of molecular diagnostics ... the United States and Europe to ... Profile information for each company in The Top 200 Molecular ...
Breaking Medicine Technology: