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Poor colonoscopy prep hides pre-cancerous polyps
Date:3/27/2012

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In the five-year span between 2004-09, 373 patients at the center were identified as having inadequate bowel preparation. Of the 133 patients who later had a second colonoscopy during the study period, 33.8 percent had at least one pre-cancerous adenoma detected in that repeat screening. And almost one in five of that group were considered to be at high risk for colon cancer because they either had more than three adenomas detected, or the test discovered at least one large lesion.

In fact, the researchers found that 18 percent of the patients who had a second colonoscopy would have been given different recommendations if their polyps and adenomas had been detected during the initial screening, such as more frequent colonoscopies to monitor the development of growths in the colon.

"It generally takes several years for an adenoma to become cancerous," Chokshi says. "But it's hard to know where in that sequence a particular adenoma is when we detect it. So it certainly is possible that any lesion we miss during a colonoscopy could develop into a malignancy before a person's next colonoscopy, especially if it doesn't happen until 10 years later."


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Contact: Jim Dryden
jdryden@wustl.edu
314-286-0110
Washington University School of Medicine
Source:Eurekalert  

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Poor colonoscopy prep hides pre-cancerous polyps
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