Navigation Links
Poniard Pharmaceuticals Presents Final Results of Phase 1 Study of Oral Picoplatin Demonstrating Bioavailability
Date:4/21/2009

- Pharmacologic Data Presented at American Association for Cancer Research's 100th Annual Meeting 2009 -

SOUTH SAN FRANCISCO, Calif. and DENVER, April 21 /PRNewswire-FirstCall/ -- Poniard Pharmaceuticals, Inc. (Nasdaq: PARD), a biopharmaceutical company focused on oncology, today announced the presentation of final data from a Phase 1 clinical study of an oral formulation of picoplatin in patients with solid tumors. Results showed that the bioavailability of oral picoplatin is nearly 100 percent at doses of 50 mg and 100 mg, indicating sufficient bioavailability to support further clinical development.

Picoplatin, the Company's lead product candidate, is a new generation platinum chemotherapy agent in clinical development to treat a variety of solid tumors. It was designed to overcome platinum resistance of the tumor, which remains a medical challenge for oncologists and patients, whose therapeutic options become limited. Poniard is currently evaluating an intravenous formulation of picoplatin in a pivotal Phase 3 trial in patients with small cell lung cancer (SCLC) and in Phase 2 trials in metastatic colorectal cancer (CRC) and metastatic castration-resistant prostate cancer (CRPC).

"The results of the Phase 1 trial demonstrating the oral bioavailability of picoplatin support the continued development of an oral formulation for multiple tumor indications," said Robert De Jager, M.D., chief medical officer of Poniard. "We believe that oral picoplatin may offer opportunities for studies in new indications and in combinations with other chemotherapeutics or with radiation therapy. The administration options for oral picoplatin may provide more convenience to cancer patients and could enable the potential of multiple combination therapies."

The picoplatin data were presented today in a poster ses
'/>"/>

SOURCE Poniard Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine news :

1. Poniard Pharmaceuticals Announces Upcoming Conference Participation
2. Poniard Pharmaceuticals Reports Second Quarter 2008 Financial Results and Corporate Update
3. Poniard Pharmaceuticals Reports Third Quarter 2008 Financial Results and Corporate Update
4. Poniard Pharmaceuticals Provides 2009 Clinical Data Goals for Picoplatin
5. Poniard Pharmaceuticals Announces Appointment of Greg Weaver as Chief Financial Officer
6. Poniard Pharmaceuticals Receives Going Concern Qualification
7. Poniard Pharmaceuticals to Present at Needham & Companys Cancer Therapeutics: Today & Tomorrow Conference
8. Poniard Pharmaceuticals to Focus Company Resources on Late-Stage Oncology Candidate Picoplatin Through Realignment of Research Organization
9. Poniard Announces Publication of Results of Picoplatin Phase 2 Study in Journal of Clinical Oncology
10. Arena Pharmaceuticals to Present at the NewsMakers in the Biotech Industry Conference
11. Schering-Plough/Merck Pharmaceuticals Announce FDA Filing Acceptance of New Drug Application for Loratadine/Montelukast Tablet
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Jose, California (PRWEB) September 30, 2014 ... are organic compounds, which are mixed with animal feed ... weight gain, and improve gut health and digestion. Amidst ... milk, eggs and meat across the globe, the need ... and aquaculture sectors is on the rise, thereby driving ...
(Date:9/30/2014)... Eastern Finland shows that dietary polyunsaturated fatty acids may ... of polyunsaturated fatty acids include fish, vegetable oils, and ... & Vascular Biology , an esteemed journal of the ... an association between the consumption of saturated fats and ... mere reduction of saturated fats from the diet does ...
(Date:9/30/2014)... Amy Norton ... News) -- Long-acting contraceptive devices should be the first ... from the American Academy of Pediatrics state. Although ... pills, two other forms of contraception -- intrauterine devices ... according to the academy. And they should be ...
(Date:9/30/2014)... Visit Pam and Steve’s quiet home in ... find a loving couple facing the most monumental challenge ... , Steve was diagnosed with ALS – more commonly ... before the couple’s second wedding anniversary. Pam is ... “Care, Support & ALS,” that’s part of ...
(Date:9/30/2014)... Neuromuscular and central nervous system ... States and worldwide. It is estimated that 50,000-60,000 ... year, adding to the more than one million ... people in the US are affected by Multiple ... statistics the 2.4 percent of the US population ...
Breaking Medicine News(10 mins):Health News:Rising Consumption of Meat and Meat Products to Fuel Growth in the Global Feed Acidifiers Market, According to New Report by Global Industry Analysts, Inc. 2Health News:Rising Consumption of Meat and Meat Products to Fuel Growth in the Global Feed Acidifiers Market, According to New Report by Global Industry Analysts, Inc. 3Health News:Dietary polyunsaturated fatty acids linked to smaller risk of coronary heart disease 2Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 2Health News:Pediatricians Endorse IUDs, Implants for Teen Birth Control 3Health News:Hospice Provides Care and Support to Patients and Family Caregivers with ALS 2Health News:North American Seminars Introduces a New OT PT CME Course, Evidence Based Rehab Techniques for Parkinsons, Multiple Sclerosis and Peripheral Neuropathy 2Health News:North American Seminars Introduces a New OT PT CME Course, Evidence Based Rehab Techniques for Parkinsons, Multiple Sclerosis and Peripheral Neuropathy 3
... Research, Inc.,(Scimitar) issues a review of StatSure Diagnostic ... for Investors Seeking,to Participate In a Proprietary Point-of-Care ... website: http://www.scimitarequity.com . ABOUT STATSURE ... development,manufacture and marketing of rapid immunoassay tests for ...
... Valve Repair Product Portfolio, MINNEAPOLIS, Oct. ... ), manufacturer and marketer of state-of-the-art cardiac,surgery ... and Drug,Administration (FDA) clearance for the ATS ... the next in a series of,mitral valve ...
... to Provide Funding and Support for "Patient Navigator,Program" ... Everett, Washington, EVERETT, Wash., Oct. 25 ... new Patient Navigator Program at,the Providence Regional Cancer ... one part of a strategic nationwide effort to,significantly ...
... for interviews, OAKLAND, Calif., Oct. 25 ... volunteer,registered nurses through its Registered Nurse Response Network ... the spreading disaster,created by wildfires in the region. ... to shelters in San Diego,County in response to ...
... House Republican Whip,Roy Blunt (Mo.) issued the following ... children,s health program created by,Republicans to expand taxpayer-funded care ... in some cases, not even in this country legally:, ... take our concerns to heart and,come back with an ...
... 25 Darwin,Professional Underwriters, Inc. (Darwin) (NYSE: ... its third quarter 2007 financial results following the,close ... conference call to,discuss the company,s third quarter 2007 ... 2007 at 8:00 a.m. Eastern Time. (Logo: ...
Cached Medicine News:Health News:StatSure Diagnostic Systems, Inc. (OTC Bulletin Board: SSUR) Review Issued By Scimitar Equity Research, Inc. 2Health News:ATS Medical Receives FDA Clearance for ATS Simulus Semi-Rigid Annuloplasty Ring 2Health News:ATS Medical Receives FDA Clearance for ATS Simulus Semi-Rigid Annuloplasty Ring 3Health News:Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca 2Health News:Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca 3Health News:Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca 4Health News:Everett-Area Cancer Patients Can More Easily Navigate Health Care System Thanks to the American Cancer Society and AstraZeneca 5Health News:CNA/NNOC Nurse Volunteers Deployed to Southern California Firestorm 2Health News:Darwin to Announce Third Quarter 2007 Financial Results 2
(Date:9/30/2014)... , Sept. 30, 2014 Headquartered in ... GWPC) is a diversified company comprised of several specialized ... advanced technology and the proven expertise of its team ... and wellness. WholeHealth Products, line of more than 10 ... centers, and its more than 8 retail consumer tests ...
(Date:9/30/2014)... N.Y. , Sept. 30, 2014  Millennium ... Millennium Medical Devices, has executed a sales, marketing ... Florida based provider of ... Accountable Care Organizations (ACOs) and hospitals through a ... serves over 10,400 active Physician Purchasing Accounts that ...
(Date:9/30/2014)...  The Corporate Whistleblower Center is urging ER ... 866-714-6466 if they have well documented proof of ... been sent home, as an intentional way to ... as the Center would like to explain. ... Photo - http://photos.prnewswire.com/prnh/20140929/149017 ...
Breaking Medicine Technology:WholeHealth Products Announces The Discovery Of The "Autism And Fragile X" Microwell And Rapid Diagnostic Test 2Millennium Healthcare Secures New Sales, Marketing and Distribution Agreement 2Millennium Healthcare Secures New Sales, Marketing and Distribution Agreement 3Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 2Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 3Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 4
... 16 The board of directors of Intarcia Therapeutics, ... Kurt Graves as executive chairman of the board. In ... leadership to the board and work closely with management ... development with its potential blockbuster asset, ITCA 650 (DUROS® ...
... ONXX ) today announced that it will present ... 22, 2010 at 3:00 p.m. Eastern Time (12:00 p.m. Pacific ... of the presentation on our website at: ... on 15 minutes early in order to register and download ...
Cached Medicine Technology:Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals 2Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals 3Onyx Pharmaceuticals to Present at the UBS Global Life Sciences Conference 2
This adjustable-volume digital micropipet is used to accurately measure and transfer small solution volumes in the 20-200 microliter range....
... and density. Proven ergonomic design reduces hand fatigue, prevents injury. Dry seal ... 20-200 ... 1.0~2.0 Imprecision(%) ... 1 Dimensions: ...
This CLS number is a new product number, created to easily match Cornings product number. If showing no availability yet, please order under the old Sigma-Aldrich number (Z71,411-9) or contact custom...
Pipetman P is a fully adjustable, air-displacement pipette with the selected volume shown on a digital indicator (volumeter). Eight models cover the full range of volumes from 0.2 L to 10 mL....
Medicine Products: