Navigation Links
Pneumatosis cystoids intestinalis after fluorouracil chemotherapy

The mechanism of pneumatosis cystoids intestinalis (PCI) is unclear. The mechanical and bacterial factors are most predominant causes of PCI. Several chemotherapeutic agents recently have been reported to be associated with PCI. Fluorouracil-related PCI has not been described previously. This present case will add to the some reports of patients with fluorouracil related toxity.

A report article to be published on 28 May 2008 in the World Journal of Gastroenterology addresses this case. The present case report is described by Dr. Mimatsu and co workers from Department of Surgery, Social Insurance Yokohama Central Hospital.

Fluorouracil is most commonly used chemotherapeutic agent in clinical oncology treatment. The cytotoxic effect of fluorouracil on intestinal epithelium can play a role in the pathogenesis of PCI. Severe erosion and ulceration in the ileum after fluorouracil chemotherapy is known. This mechanism is thought to be many factors including alteration of the local mucosal blood flow, and thrombosis and vasospasm on the intestinal epithelium. The mechanism of fluorouracil-related PCI is also thought to be a multifactolial bowel toxicity caused by fluorouracil itself. The present case report lead us conjuncture that the possibility of developing PCI in patients undergoing fluorouracil chemotherapy should be kept in mind.


Contact: Lai-Fu Li
World Journal of Gastroenterology

Page: 1

Related medicine news :

1. Work-Family Conflict Dogs Air Force Women After Deployment
2. Work-Family Conflict Dogs Air Force Women After Deployment
3. Stopping Statins After Stroke Doubles Death Risk
4. Billy Graham Home After Hospitalization:
5. Swelling After Knee Injury May Hinder Healing
6. Going on After Loss
7. Discover The Mutter Museum After Dark
8. Cialis Eases Erectile Dysfunction After Spinal Cord Injury
9. Perrigo Vice Chair Mori Arkin To Retire After 30 Years of Service
10. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
11. Pill Equals Injection in Preventing Clots After Hip Replacement
Post Your Comments:
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users ... - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 ... Pro X . Simply select a ProHand generator and drag it above media or ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Scientific Sessions in Dallas that it will receive two significant new grants to ... came as PHA marked its 25th anniversary by recognizing patients, medical professionals and ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their ... Award, an essay contest in which patients and their families pay tribute to a ... the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners is ... sequencing and genomics experience, as Vice President of North American Capital Sales at ... for leading the sales team in the commercialization of the HTG EdgeSeq system and ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/26/2016)... , June 26, 2016 ... value-based care operating models within the health care industry ... greater financial efficiency , Deloitte offers a suite ... key business issues impacting efficient cost optimization: labor resource ... , These services facilitate better outcomes and better economics ...
(Date:6/24/2016)... 24, 2016  Collagen Matrix, Inc., ("Collagen Matrix") ... manufacturing of collagen and mineral based medical devices ... Bill Messer has joined the company ... leverage the growing portfolio of oral surgery, neurosurgery, ... Bill joins the Collagen Matrix executive team as ...
Breaking Medicine Technology: