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Pluripotent stem cell-derived neurons may be a viable Parkinson's disease treatment
Date:6/28/2013

r results demonstrate that pluripotent stem cell line-derived neurons retain the capacity to robustly survive and respond to cues in the primate brain," they wrote. "The absence of TH expression indicates that other methods may be necessary to produce and maintain the proper midbrain dopaminergic form of the cells in vivo."

While their study demonstrated robust survival of the cells, the researchers said that longer term studies are required to better understand what factors may impact long-term function replacement and whether they demonstrate significant reversal of parkinsonism, tumor formation or dyskinesias, the latter being a side effect of current treatments for Parkinson's Disease.


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Contact: Robert Miranda
cogcomm@aol.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

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