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Plavix Plus Heartburn Drugs May Hike Heart Risk
Date:1/28/2009

: "This [the Canadian report] is very worrying to us doctors who prescribe clopidogrel and proton pump inhibitors. The FDA has said it is reviewing all the data on this issue. All of us are on notice that something is going on."

Epstein said: "The take-home message is that if you are taking Plavix, you should continue to take it. The question is whether you should take a proton pump inhibitor."

More information

The complete safety warning is available from the U.S. Food and Drug Administration.



SOURCES: David N. Juurlink, M.D., Ph.D., head, division of clinical pharmacology and toxicology, Sunnybrook Health Sciences Centre, Toronto, Canada; Robert Epstein, M.D., chief medical officer, Medco Health Solutions, Franklin Lakes, N.J.; Christopher Cannon, M.D., cardiologist, Brigham and Women's Hospital, Boston; Jan. 28, 2009, Canadian Medical Association Journal, online


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