The authors of the first study, from the University of Athens Medical School in Greece, compared blood BPA levels in 71 women with PCOS and 100 healthy women.
Levels of BPA in the blood of healthy-weight women with PCOS were 60 percent higher as compared with controls. BPA levels were 30 percent higher in obese women with PCOS.
And the higher the BPA level, the higher the levels of male hormones.
But, cautioned Dr. Diana Wu, a clinical fellow in reproductive endocrinology and infertility at Center for Reproductive Health, University of Cincinnati, "This is an association study. You can't really determine cause-and-effect."
The second study found that male rats whose mothers were fed BPA while they were pregnant and then breastfeeding produced less testosterone than rats who had not been exposed to BPA.
The effects lasted into adulthood and after exposure had been stopped.
The exposure levels were below those considered safe by the FDA and the Environmental Protection Agency, the authors stated.
"We used very low doses compared to levels that the population is exposed to," said study lead author Dr. Benson T. Akingbemi, associate professor of anatomy and developmental biology at Auburn University's College of Veterinary Medicine in Auburn, Alabama. "And the effects due to BPA that were caused early in development remained into adulthood."
While this study may have looked at low levels, many BPA animal studies use BPA levels well beyond what humans would normally experience, thus making the totality of the evidence, "controversial," Wu said.
In the meantime, one representative of the chemicals industry defended BPA's overall safety.
A statement from Steven Hentges, executive director of the Pol
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