Navigation Links
Pivotal study in Africa finds that HIV medications prevent HIV infection
Date:7/13/2011

In a result that will fundamentally change approaches to HIV prevention in Africa, an international study has demonstrated that individuals at high risk for HIV infection who took a daily tablet containing an HIV medication either the antiretroviral medication tenofovir or tenofovir in combination with emtricitabine experienced significantly fewer HIV infections than those who received a placebo pill. These findings are clear evidence that this new HIV prevention strategy, called pre-exposure prophylaxis (or PrEP), substantially reduces HIV infection risk.

The study is led by the University of Washington's International Clinical Research Center and involves 4,758 HIV serodiscordant couples, in which one partner has HIV and the other does not, from nine research sites in Kenya and Uganda.

"This study is the largest study to date looking at the effectiveness of PrEP," said Dr. Connie Celum, a UW professor of global health and medicine and the principal investigator of the study, known as the Partners PrEP Study.

The study is funded by the Bill & Melinda Gates Foundation.

"This study demonstrates that antiretrovirals are a highly potent and fundamental cornerstone for HIV prevention and should become an integral part of global efforts for HIV prevention," said Celum.

Study results through May 31, 2011, were reviewed on July 10, 2011, by the Partners PrEP Study Data and Safety Monitoring Board (DSMB), an independent group of experts that monitored the study's conduct, safety, and effect of PrEP on preventing HIV infections on an ongoing basis. Due to the strong HIV prevention effect seen, the DSMB recommended that the Partners PrEP Study results be made public and the placebo arm of the study be discontinued.

The DSMB also recommended that the study continue: those receiving tenofovir (TDF) and tenofovir combined with emtricitabine (FTC/TDF) PrEP will remain on those medications and those receiving placebo will sta
'/>"/>

Contact: Toni Maddox
tmaddox@uw.edu
206-520-3825
University of Washington - Health Sciences/UW News, Community Relations & Marketing
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Professor Zvi Ram presents phase III recurrent glioblastoma survival and quality of life data from the first pivotal study of the NovoTTF-100A at 15th Annual Society for Neuro-Oncology Scientific Meeting
2. Moms Literacy Pivotal to Kids Academic Success
3. Award to honor pivotal career in speech research
4. Pivotal study finds link between PTSD and dementia
5. Second-line CML drug evokes faster response, fewer side effects, pivotal study finds
6. Pivotal data for the investigational treatment PSD502 for primary premature ejaculation
7. UAB researchers present a study on the psychological adaptation of adopted children
8. Bed Sores Afflict More Blacks in Nursing Homes Than Whites: Study
9. More U.S. Men Die From Cancer Than Women: Study
10. Older Women at Greater Risk for Common STD, Study Suggests
11. Bladder Cancer Patients Not Getting Recommended Care: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2015)... May 03, 2015 “ BolehVPN ” was ... which features the latest and coolest technology products available to ... NewsWatch, conducted the review and shared with viewers how to ... does these days is on computers and even more so ... and meet people all over the world. In terms of ...
(Date:5/3/2015)... It is not too late to register to take part ... Lissa Anne Been in Arnold, Missouri on May 9, 2015. ... honor her loving memory. It has benefited the renowned Brain Aneurysm ... 37, Lissa suffered a brain aneurysm . After two operations ... event is designed to serve as a remembrance of her and ...
(Date:5/2/2015)... 02, 2015 Vancouver fencing company, QS Fencing, ... valuable advice to prospective clients related to their questions on ... install railings around their decks and patios. While that seems ... pop up once the person rolls up their sleeve to ... a railing in finding a gate that matches it. , ...
(Date:5/2/2015)... Delray Beach, FL (PRWEB) May 02, 2015 ... newspaper has selected The Delray Recovery Center as one ... Recovery Center is known in the addiction treatment field ... encourages staff members to innovate and to continue their ... promoting a positive workplace environment, never forgetting their purpose ...
(Date:5/2/2015)... (PRWEB) May 02, 2015 As ... laxity issues of the face, neck and décolleté, ... concept with real potential for the success of ... the ThermiHealth Clinical Advisory Council, ThermiGyn’s Women’s Health ... FACS, ACGE, concluded that ThermiGyn’s temperature controlled radio ...
Breaking Medicine News(10 mins):Health News:A Method to Keep Private Information Secure was Featured on NewsWatch Television 2Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Professional Staff at QS Fencing Company Now Provides Advice on Railings and Gates 2Health News:The Delray Recovery Center Named 2015 Top Workplace 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 3
... was first reported in the Luanda province of Angola on ... cholera// and 22 cholera related deaths have been reported in ... published by the World Health Organization, 101 new cholera and ... 24 hours. 8 municipalities have been reported to be affected ...
... children suffer from atopic eczema, a disease which causes the ... for new ways// to develop useful and powerful drug so ... eczema. ,Azathioprine is a drug that was developed ... their new organ. Its mechanism of action is by suppressing ...
... Nurses will now work for birth control in all the ... incidence of teenage pregnancies//. ,There are currently 2,409 nurses ... but the latest announcement signals a massive extension, reported the ... primary care trust will be funded to have at least ...
... new low nicotine Quest? cigarettes seems to have lulled ... a study conducted by researchers// at the Transdisciplinary Tobacco ... of Medicine.Results of the study have been published in ... author of this study, Caryn Lerman, PhD, Associate Director ...
... by the New England Research Institutes in collaboration with Yale ... too little// are at a greater risk of developing type ... on studies done on over 1709 men, in the age ... period of 15 yrs. ,According to the lead ...
... treatment of tuberculosis in the state would be achieved ... care sectors and NGOs, said health minister R Ashok, ... of the International TB day celebrations. ,The ... National Tuberculosis Control Programme (RNTCP) as being responsible for ...
Cached Medicine News:
(Date:5/1/2015)...   Heska Corporation (NASDAQ: HSKA - ... advanced veterinary diagnostic and other specialty veterinary products , ... present at the 16th Annual B. Riley & Co. Investor ... conference will be held May 12-14, 2015 at Lowes Hollywood ... will be available during the day on May 13 for ...
(Date:5/1/2015)... , May 1, 2015 ... expanded its current therapeutic focus beyond addiction ... serious psychiatric disorders. Braeburn has acquired an ... second-generation) antipsychotic risperidone for treatment of schizophrenia ... Braeburn acquires global rights to other potential ...
(Date:5/1/2015)... May 1, 2015  Boston Scientific Corporation (NYSE: ... business momentum and long-term growth strategies at a meeting ... York City . President and Chief Executive Officer ... the company has to bring forward meaningful innovation to ... and deliver shareholder value. "We are ...
Breaking Medicine Technology:Heska to Present at the 16th Annual B. Riley & Co. Investor Conference 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 2Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 3Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 4Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 5Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 6Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 7
... NASHVILLE, Tenn., May 4, 2011 Cumberland Pharmaceuticals Inc. ... focused on hospital acute care and gastroenterology markets, today announced ...   For the three months ended March 31, 2011, net ... corresponding period in 2010. Revenue grew year-over-year despite a brief, ...
... May 4, 2011The U.S. Food and Drug Administration ... manufacture, market, or distribute over-the-counter (OTC) liquid drug ... to measure and dispense the doses of medication. ... The guidance, titled Dosage Delivery Devices for ...
Cached Medicine Technology:Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 2Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 3Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 4Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 5Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 6Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 7Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 8Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 9Cumberland Pharmaceuticals Reports First Quarter 2011 Financial Results 10FDA Issues Final Guidance for Liquid OTC Drug Products With Dispensing Devices 2FDA Issues Final Guidance for Liquid OTC Drug Products With Dispensing Devices 3
... System is a single-use, disposable needle loading ... into a Bard BrachyStar needle for interstitial ... radiation safety shield, inner compartment that holds ... fitting that connects the cartridge to the ...
... Holter Monitoring System uses technology developed by ... first true 12-lead digital Holter recorder in ... beat contained in the 24-hour study provides ... work done by the Q-12 digital recorder ...
Data review and analysis is carried out with the Acquidata Uromac software already supplied with Acquidata Uromac Lab based urodynamics systems...
... any clinical setting, offering an exclusive ... procedure. Customize Delphis™ to your exact ... Pocket PC, a Touchpad PC Tablet ... technology allows you to focus on ...
Medicine Products: