Navigation Links
Pint-size microRNAs show promise against weighty problem, researchers say
Date:9/6/2012

Tiny strands of RNA affect how our cells burn fat and sugar a finding that gives biologists a place to start in the quest for therapies to treat obesity and related health problems, said scientists at Virginia Tech and the University of Texas Southwestern Medical Center at Dallas.

Mice on high fat diets are resistant to obesity when two mini-molecules called microRNAS are missing from their genetic makeup, according to a study this week in the Proceedings of the National Academy of Science

The discovery suggests that treatments targeting these two specific microRNAs may help stem the nation's obesity epidemic. More than one-third of adults in the United States and about 17 percent of the nation's children are obese, increasing their risk for type 2 diabetes, heart disease, stroke, liver disease, and some cancers, according to the National Institutes of Health.

"Scientists know the best health solution for obesity involves eating less and exercising more," said Matthew W. Hulver, Ph.D., an associate professor with the Department of Human Nutrition, Foods, and Exercise in the College of Agriculture and Life Sciences at Virginia Tech. "But in cases when people can't or won't exercise, if we can identify what is contributing to the regulation of our metabolic circuits, we can target it with a drug or pharmacologic solution."

Once considered to be little more than scrap DNA, scientists now know microRNAs have an important role in regulating how genes shape human health and behavior. They have been linked to heart disease, diabetes, hepatitis C, leukemia, lymphoma, and breast cancer.

Although microRNAs previously have been linked to obesity, the new findings are the first to establish a connection between microRNAs and cellular metabolism.

MicroRNA biologists at UT Southwestern Medical Center modified mice to be genetically unable to produce microRNA-378 and its cousin miR-378*, resulting in relatively trim anima
'/>"/>

Contact: John Pastor
jdpastor@vt.edu
540-231-5646
Virginia Tech
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Alzheimers Drug Shows Some Promise in Trials
2. Rewired visual input to sound-processing part of the brain leads to compromised hearing
3. Green tea compound shows promise for tackling cancer
4. Male Birth Control Drug Shows Promise in Mice
5. Therapy combining exercise and neuroprotective agent shows promise for stroke victims
6. In Mice, Alzheimers-Linked Protein Shows Promise Against MS
7. Stem Cells Show Promise as Heart Failure Treatment
8. Alzheimers Drug Shows Promise in Early Trial
9. A nursing program shows promise for reducing deaths from chronic illnesses
10. Alzheimers Treatment Shows Promise in Small, 3-Year Trial
11. New gene transfer strategy shows promise for limb girdle and other muscular dystrophies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... York (PRWEB) October 25, 2014 ... lawsuits ( http://www.vaginalmeshlawsuit2015.com/ ) filed against Boston ... in U.S. District Court, Southern District of West ... Judgment on Punitive Damages in a group of ... a ruling issued on October 21st, U.S. District ...
(Date:10/25/2014)... 25, 2014 Limbkeepers® announced today that ... Innovations with Ed Begley Jr, airing 1st QTR 2015 ... In this episode, Innovations will focus on Limbkeepers® non ... fragile, thinning skin on arms, hands, and legs from ... these versatile products, which help reduce injuries, allow for ...
(Date:10/25/2014)... By Steven Reinberg ... -- The virus that causes common cold sores -- herpes ... studies by Swedish researchers suggest. In fact, being a ... risk of Alzheimer,s disease, the researchers found. "The ... common dementia disorder is a breakthrough," said lead researcher Dr. ...
(Date:10/25/2014)... -- Researchers who discovered antibiotics in farmed and ... concern. The use of antibiotics in animals, ... contribute to the development of antibiotic-resistant bacteria that ... the study. Each year in the United ... and kill about 23,000, according to the Infectious ...
(Date:10/25/2014)... Current osteoporosis screening guidelines and tools fail to ... osteoporosis-related fractures, a new study says. "If ... that help us accurately predict who will suffer ... these at-risk people for preventive measures," study author ... division of general internal medicine and health services ...
Breaking Medicine News(10 mins):Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 2Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 3Health News:Transvaginal Mesh Lawsuits Move Forward, As Federal Judge Denies Motion for Summary Judgment on Punitive Damages in Florida Cases, Bernstein Liebhard LLP Reports 4Health News:Upcoming Episode of Innovations with Ed Begley, Jr. to Feature Limbkeepers® 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 3Health News:Researchers Say Antibiotics in Fish a Health Concern 2Health News:Osteoporosis Screening Guidelines May Miss Younger Women at Risk 2
... home importance of awareness and,education of kidney disease, which ... Calif., Oct. 16 In a nationwide,effort to raise ... focusing on raising awareness of kidney disease among 20 ... the nation,s,largest independent dialysis provider, announced today that its ...
... A small capsule that takes snapshots of the small ... doctors spot cases of Crohns disease that had gone ... at Wake Forest University Baptist Medical Center. , Reporting ... in Philadelphia, the researchers said that of 198 video ...
... leading provider of,Business Process Integration solutions for ... filled three Director-level positions based at the,company,s ... Thompson,Director of Data Management; Darryl Means, Director ... Healthcare Operations. (Logo: http://www.newscom.com/cgi-bin/prnh/20050113/SFTH042LOGO ) ...
... ... Oct. 16 With the percentage of,overweight American children and ... milk?" Milk Mustache Campaign is recognizing 10,pediatricians across the nation ... obesity crisis into their own hands. Since 1991, the ...
... When you are healthy,purchasing disability insurance can ... financial asset: your,ability to earn a living, says ... care insurance lawyer. (Photo: http://www.newscom.com/cgi-bin/prnh/20070717/NYFNSC02 ... you want to make sure you,buy the right ...
... ROCHESTER, N.Y., Oct. 16 Many routine surgical ... dermatologists may soon be sharing,reviewing and diagnosing noninvasive ... Lucid Inc.,s VivaNet(TM) telemedicine server and its,VivaScope(R) confocal ... special microscopes to digitally,image a patient,s skin, may ...
Cached Medicine News:Health News:DaVita Volunteers Raise More than $1,000,000 for Nationwide Kidney Education and Prevention Programs 2Health News:Capsule endoscopy turning up undiagnosed cases of Crohn's disease 2Health News:Three New Director-Level Appointments at Adaptis 2Health News:Three New Director-Level Appointments at Adaptis 3Health News:Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity 2Health News:Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity 3Health News:Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity 4Health News:Why Healthy People Should Consider Individual Disability Insurance 2Health News:VivaScope(R) Confocal Imager May Eliminate Need for Routine Skin Biopsies for Dermatology Patients 2
(Date:10/22/2014)... HAMILTON, N.J. , Oct. 22, 2014 ... CLIA-certified, CAP-accredited laboratory which specializes in high ... that it is now offering new Cystic ... including next- generation DNA sequencing platforms. ... a genetically inherited multisystem disorder that affects ...
(Date:10/22/2014)... Antigen Discovery Inc. (ADi), a privately held ... the receipt of a National Institutes of Health (NIH) ... Institute of Dental and Craniofacial Research (NIDCR). The one-year ... Protein Microarray Chip, which will contain every protein in ... in the development of safe and effective vaccines and ...
(Date:10/22/2014)... -- AVACEN Medical announced today that its AVACEN 100 ... by the U.S. Food and Drug Administration. This clearance ... Internet for: the temporary relief of joint pain ... sprains . Logo - http://photos.prnewswire.com/prnh/20141021/153513 ... a sophisticated medical device incorporating over 3,000 firmware instructions ...
Breaking Medicine Technology:Medical Diagnostic Laboratories, L.L.C. Institute for Biomarker Research Announces New Prenatal Cystic Fibrosis Tests 2Biomarker Discovery Company, Antigen Discovery Inc., Awarded an NIH Phase I Small Business Innovation Research Grant to Develop a Pan-HIV Protein Microarray Chip 2AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2
... May 11, 2012  Amgen (NASDAQ: AMGN ) ... vice president of Research and Development at Amgen will ... Administration (FDA) stakeholder hearing on biosimilars. Miletich will urge members ... for biosimilars to establish approval standards that advance patient ...
... Mylan Inc. (Nasdaq: MYL ) today ... mg, 20 mg, 40 mg and 80 mg in ... has received marketing authorization from each country,s respective health ... is the generic version of Pfizer,s Lipitor® Tablets. This ...
Cached Medicine Technology:Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars 2Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars 3Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars 4Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars 5Amgen To Provide Testimony At FDA Stakeholder Hearing On Biosimilars 6Mylan Launches Generic LipitorĀ® in Five European Countries 2
Bench Top Horizontal (clean bench) Airflow Cabinet...
... chamber provides a safe, clean environment ... in accord with USP-797 requirements. HEPA ... 5) cleanliness conditions in the work ... and tilt-up front panel for easy ...
... testing at various temperatures, this chamber ... a clean heating unit to maintain ... 140F. Transparent panels allow full visibility, ... access to the work area. Includes ...
... and removes chemical fumes, allowing ... Bonded charcoal filters remove most ... safe exhaust flow speed = ... opening. Includes air speed monitor, ...
Medicine Products: