Navigation Links
Pine bark reduces inflammatory marker CRP in osteoarthritis

Osteoarthritis (OA), a type of arthritis caused by the breakdown and loss of cartilage, affects more than 20 million Americans. While the most common prescription to treat OA is non-steroidal anti-inflammatory drugs (NSAIDs), many seek alternative treatments because of the side effects associated with these drugs. Pycnogenol (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, has been shown to reduce osteoarthritis in multiple studies. A study published in the current issue of the journal Redox Report, reveals Pycnogenol's anti-inflammatory potency further to improving OA symptoms and pain was able to significantly lower plasma levels of C-reactive protein (CRP). With disease progression of osteoarthritis, the inflammation may reach a level where it no longer is limited to the affected joint and stresses the organisms, which in turn increases the inflammatory marker CRP in the blood.

The current study, a joint effort between Italy's Chieti-Pescara University and the University of Munster, Germany, investigated a subset 55 patients from a previous osteoarthritis with 156 patients who had significantly elevated CRP levels. Treatment consisted of two tablets daily of either 50 mg Pycnogenol or placebo. Blood specimens were drawn at baseline of the initial study and again after three-month treatment. Results showed that Pycnogenol significantly lowered CRP from average 3.9 mg/L at baseline to 1.1 mg/L, reflecting essentially healthy levels. In the placebo group a marginal lowered CRP level was detected. Other blood parameters indicative of acute inflammation likewise decreased with Pycnogenol, such as fibrinogen (lowered 37.1 %) and reactive oxygen species (lowered by 29.9 %).

"The decrease of systemic inflammatory markers, particularly CRP, suggests Pycnogenol properties may be potent enough to arrest the spread of inflammation from osteoarthritic joints to the whole organisms" said Dr. Peter Rohdewald, a lead researcher of the study. "When inflammatory processes are allowed to reach the whole body the degenerative processes may burden overall health including increased cardiovascular risks."


Contact: Melanie Nimrodi
MWW Group

Related medicine news :

1. Prostate cancer drug reduces testosterone levels in as little as 3 days
2. New Data: Advanced Pharmacy Model Significantly Reduces Gaps in Care for Patients with Chronic and Complex Conditions; Improves Clinical and Financial Outcomes
3. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
4. Hepatitis C Therapeutic DNA Vaccine Delivered by Inovio Biomedical's Electroporation Technology Reduces Viral Load by Up to 99.7% : Clinical Data Presented at Annual Scientific Meeting of the American Association for the Study of Liver Diseases
5. Interferon Reduces, Eliminates Viral Infections in Heart Failure Patients
6. Tailored Drug Delivery Reduces Adverse Effects After PCI
7. Statin Reduces Heart Attack, Stroke Rates in Patients With Normal Cholesterol but Elevated C-Reactive Protein
8. The Results From a Clinical Trial Led by the Montreal Heart Institute Demonstrate That Drug Reduces Inflammation in Patients With Serious Cardiovascular Disease
9. Study shows pine bark reduces jetlag
10. Study Shows Pine Bark Reduces Jetlag
11. Healthy bones program reduces hip fractures by 37 percent
Post Your Comments:
(Date:11/24/2015)... City, UT (PRWEB) , ... November 24, 2015 , ... ... Forbes Magazine. For a business, it is critical that the first impression be positive ... business, they are not likely to buy anything or want to return. They will ...
(Date:11/24/2015)... ... 2015 , ... In response to recent news highlighting Oxycodone fraud, Novus Medical ... the United States grew 400 percent between 1999 and 2010, far more than the ... percent of all fatal drug overdoses. (1) , While oxycodone and the extended release ...
(Date:11/24/2015)... ... November 24, 2015 , ... The American Association ... their local poison centers through donations on Tuesday, Dec. 1, 2015. Since 2012, ... day that inspires people to collaborate in improving their local communities and help ...
(Date:11/24/2015)... ... 24, 2015 , ... With Thanksgiving right around the corner, holiday travel season ... protect your family and vehicle. , According to the National Highway Traffic Safety Administration, ... is sharing the following safety tips from the NHTSA: , ...
(Date:11/24/2015)... ... November 24, 2015 , ... Abington Hospital ... Aetna Institute of Quality® Bariatric Surgery Facility for treating individuals living with morbid ... health care services available to its members to help them make informed decisions ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015   HeartWare International, Inc ... less-invasive, miniaturized circulatory support technologies that are revolutionizing the ... and Chief Executive Officer Doug Godshall is ... Annual Healthcare Conference on December 1, 2015 at ... 1-2 in New York . ...
(Date:11/24/2015)... 24, 2015  Ascendant Solutions, Inc. (Pink Sheets: ASDS ... of Directors has declared a special 1 percent stock dividend ... payable December 14, 2015, to shareholders of record December 7, ... additional shares of common stock. --> ... a strong endorsement of our confidence in Ascendant,s growth strategy ...
(Date:11/24/2015)... Nov. 24, 2015  Figure 1, a free mobile-first ... medical cases, has launched a new completely redesigned web ... version allows radiologists, who work primarily on a desktop, ... engage with its radiologist user base, Figure 1 is ... North America (RSNA) Annual Meeting. ...
Breaking Medicine Technology: